Clinical trials: Elective Operation Patients
Chronic Pain
Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery
This is a randomized, prospective, double-blind , placebo-controlled trial examining the effects of intraoperative dexmedetomidine infusion on pain in patients undergoing lumbar spinal fusion surgery.
- Trial name
- NCT03325972
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- NYU Langone Health
Erector Spina Plan Block, Preemptive Analgesia
Comparison of the Effect of Preemptive and Post-operative Erector Spina Plane Block on Intraoperative Opioid Consumption and Postoperative Analgesia in Patients Who Will Undergo Elective Thoracotomy Surgery, Guided by the Nociception Level Index (NoL)
The patients who will participate in the study will be determined and informed according to the inclusion and exclusion criteria, and the patients who signed the informed consent form will be included in the study.52 patients who…
- Conditions
- Erector Spina Plan Block, Preemptive Analgesia, Thoracotomy, Nociception Level Index(NoL)
- Trial name
- NCT05944523
- Testing
- Erector Spina Plan Block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara University
Frailty
Intraoperative EEG Marker of Preoperative Frailty in Elderly Patients
Frailty is a state of vulnerability, characterized by a loss of mechanisms that maintain homeostasis, determining a lower capacity for recovery in the event of a stressful incident.
- Trial name
- NCT04783662
- Testing
- Intraoperative frontal electroencephalogram
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain, IL-1 Beta
Comparison of the Ultrasound Guided Effects of the Erector Spina Plane Block and Quadratus Lumborum Block Methods on Postoperative Analgesia and Plasma Cytokine Levels in Elective Cesarean Operations
Comparison of Two Different Analgesic Techniques for Reducing Postoperative Pain After Cesarean Section
- Trial name
- NCT07901829
- Testing
- QL (quadratus lumborum) block, Erector Spinae Plane Block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Education and Research Hospital
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Postoperative Cognitive Dysfunction
Effects of Amantadine on Postoperative Cognitive Dysfunction
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Investigators will determine whether amantadine can reduce the occurrence of POCD in elderly patients with major abdominal surgery.
- Trial name
- NCT03527134
- Testing
- Amantadine
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Zhiyi Zuo
Trauma, Surgery
Sublingual Sufentanil PCA Usability for Postoperative Pain (Zalviso® System)
Intravenous patient-controlled analgesia (iv-PCA) is the gold standard for the treatment of moderate to severe postoperative pain. It is used in more than 20% of cases after major surgery.
- Trial name
- USE-SSPC (NCT03373851)
- Testing
- Zalviso Device
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Hospices Civils de Lyon
Abdominal Surgery
Remote Telemonitoring to Improve Prehabilitation and Surgical Outcomes of Patients Undergoing Elective Abdominal Surgery
There is data confirming that simple tests of physical capability, such as the timed "get-up-and-go" test and the 6-minute walk test, correlate with surgical outcomes.
- Trial name
- NCT03706963
- Testing
- Phone Call
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Washington University School of Medicine
Elective Coronary Artery Bypass Graft Surgery
Colchicine in Coronary Artery Bypass Graft (CABG)
There is evidence that inflammatory processes may play a key role during surgical myocardial reperfusion. The hypothesis of this study is that colchicine, an anti-inflammatory agent, may lead to reduction in periprocedural…
- Trial name
- NCT02122484
- Testing
- Colchicine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- G.Gennimatas General Hospital
General Anesthesia
Effect of Tegoprazan for Elective Surgery Patients Under General Anesthesia
The aim of this study is to compare gastric pH right after endotracheal intubation for general anesthesia in patients pretreated with tegoprazan, famotidine, or placebo.
- Trial name
- NCT06743243
- Testing
- Tegoprazan, Famotidine
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seok Kyeong Oh
Total Knee Replacement Surgery
The Impact of Sedation Depth Monitoring for Cognitive Functions and Early Rehabilitation After Major Joints Arthroplasty
Spinal anesthesia is applied for patients undergoing total elective knee replacement surgery. It reduces rates of postoperative complications, improves postoperative pain management, rehabilitation is started earlier and patients…
- Trial name
- NCT06241859
- Testing
- Dräger Infinity Delta series monitor (Dräger, Germany) with Covidien BIS LoC 2 channel module and BIS Quatro (4 electrodes) sensor (Covidien, Ireland)
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Adult Patient Undergoing Elective Surgery With General Anesthesia and Needs Nasogastric Tube Placement
Nasogastric Tube Placement on Intubated Patient: Two-Finger Method vs Reverse Sellick's Maneuver
The study aimed to compare the efficacy between nasogastric tube placement using Two-Finger Method and Reverse Sellick's Maneuver
- Trial name
- NCT03134287
- Testing
- two-finger method, reverse sellick's method
- Where
- Indonesia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cervical Spine Fusion
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients…
- Trial name
- MCP (NCT05996133)
- Testing
- Bupivacaine Hcl 0.25% Inj, Normal saline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hartford Hospital
Difficult / Failed Intubation
NC/TMD Ratio As a Difficult Airway Predictor in Obese Patients
To assess accuracy of NC/TM distance ratio in terms of sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) for predicting difficult intubation in obese patient with Intubation difficulty…
- Trial name
- NCT05735106
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- KRL Hospital, Islamabad
Post-induction Hypotension (PIH), Gastrointestinal Tumor Surgery
Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery
This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid…
- Trial name
- NCT07777159
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Ankara City Hospital Bilkent
Hypothermia, Complications
Impact of Expanded Peri Operative Warming
The purpose of this proposed study is to evaluate a normothermia protocol that includes preoperative warming and standard intra operative temperature management in patients undergoing general surgery.
- Trial name
- NCT01649596
- Testing
- Warming Gown, Standard of care warming
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Kinesiophobia
Kinesiophobia, Postoperative Pain, and Early Mobilization After Elective Abdominal Surgery
This study examines the level of kinesiophobia (fear of movement) in patients undergoing elective abdominal surgery and its relationship with postoperative pain severity and early mobilization.
- Trial name
- NCT07834554
- Testing
- Tampa Scale for Kinesiophobia (TSK)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Volkan Gokmen
Oxidative Stress, Cognition Disorders
The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Objective: The aim of this study was to determine the effect of dexmedetomidine in reducing postoperative cognitive dysfunction (POCD) in cardiac surgical patients which use cardiopulmonary bypass machine (CPB).
- Trial name
- NCT03054857
- Testing
- Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Dreaming, General Anesthesia
Dreaming During Anesthesia and Anesthetic Depth in Elective Surgery Patients Under General Anesthesia
Dreaming is a common, enduring, and fascinating part of the anesthetic experience, but its cause and timing remain elusive. Patients typically report that they were dreaming during anesthesia, but the actual timing of anesthetic…
- Trial name
- NCT05357872
- Testing
- deep anesthesia depth, light anesthesia depth
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital