Clinical trials: Elective Operation Patients
Gastric Insufflation, I-gel
Gastric Insufflation Volume Using I-gel Versus Ambu AuraGain in Pediatric Patients Undergoing Elective Orthopedic Operations Under General Anesthesia
Our study aimed to compare the gastric insufflation volume between Ambu AuraGain and i-gel and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications in generally anesthetized…
- Conditions
- Gastric Insufflation, I-gel, Ambu AuraGain, Pediatric
- Trial name
- NCT06853756
- Testing
- Ambu Auragain, I-gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Elective Surgical Patients
Comparison of Glottic Views and Intubation Times in the Supine and 25 Degree Back-up Positions
Our hypothesis is that the view of the glottis may be improved by putting all patients requiring intubation in the ramped or back up position while maintaining the classic sniffing position.
- Trial name
- NCT02934347
- Testing
- 25 degree back-up position
- Volunteers
- 781 people
- Sponsor
- Betsi Cadwaladr University Health Board
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Anesthesia, Fasting
The Effect of Mobilization on Gastric Emptying Time
ıntroduction Pulmonary aspiration under general anesthesia is a rare but serious complication in healthy patients undergoing elective surgery.
- Trial name
- NCT05981638
- Testing
- group WM, group WR, Group AR
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Uludag University
Ultrasound, Difficult Laryngoscopy
Ultrasonographic Parameters in Prediction of Difficult Laryngoscopy in Non-suspected Difficult Airway Patients
This study aims to evaluate the ultrasonographic parameters (distance from skin to epiglottis (DSE) and distance from skin to vocal cords (DSVC)) as preoperative predictors of difficult laryngoscopy in non-suspected difficult…
- Conditions
- Ultrasound, Difficult Laryngoscopy, Prediction
- Trial name
- NCT06052189
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Cardiac Disease
Patient Preferences and Experiences of Waiting for Heart Surgery
Waiting for heart surgery could be difficult and anxiety-provoking for some patients. Research suggests that some specific factors (e.g., individual coping strategies, communication with the clinical team, having a more active…
- Trial name
- NCT05996640
- Testing
- This is study does not use an intervention
- Volunteers
- 268 people
- Sponsor
- King's College London
Mechanical Ventilation Complication, Intensive Care Unit
INTELLiVENT-ASV Using Mainstream Versus Sidestream End-Tidal CO2 Monitoring
Background INTELLiVENT-ASV, an automated closed-loop mode of mechanical ventilation, available on Hamilton ventilators for clinical use, uses mainstream end-tidal CO2 (etCO2) monitoring to adjust minute ventilation.
- Conditions
- Mechanical Ventilation Complication, Intensive Care Unit, Postoperative Care
- Trial name
- INTELLiSTREAM (NCT04599491)
- Testing
- Sidestream capnography using the 'Respironics LoFlo Sidestream CO2 Module', Mainstream capnography using the 'Respironics Capnostat 5 Mainstream CO2 sensor'
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Airway Ultrasound Indices, Clinical Airway Assessment
Airway Ultrasound Indices for Prediction of Difficult Laryngoscopy in Pediatric Patients
The goal of this observational study is to compare the airway ultrasound indices and the preoperative clinical airway assessment concerning the difficult laryngoscopic view in paediatric patients undergoing elective surgery under…
- Trial name
- NCT07185516
- Testing
- Airway ultrasound indices, Clinical airway assessment
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intensive Care, Surgical
Postoperative Delirium in Adult Patients After Elective Craniotomy Under General Anaesthesia
Postoperative delirium may result in many adverse complications. At present little is known about postoperative delirium in patients after crniotomy because they may manifest similar symptoms to definitely delirium for some…
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT03087838
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Capital Medical University
Venous Thromboembolism
Pharmacokinetic (PK) Assessment of BIBR 1048 in Patients After Primary Elective Total Hip Replacement Surgery
To determine the PK profile of a single dose 150 mg BIBR 1048, oral capsule, administered 1-3 hours post surgery in hip replacement patients.
- Trial name
- NCT02170935
- Testing
- BIBR 1048 capsule
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Surgery
Ultrasound-guided Thoracic Paravertebral Block Using Ropivacaine With/Without Dexamethasone in Elective Thoracotomy
The procedures of thoracotomy are among the most painful operations. In addition to post-thoracotomy pain, the outcomes of surgery are affected adversely by postoperative discomfort.
- Trial name
- NCT02871193
- Testing
- Ropivacaine, Dexamethasone, saline
- Where
- China
- Volunteers
- 68 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Difficult / Failed Intubation
NC/TMD Ratio As a Difficult Airway Predictor in Obese Patients
To assess accuracy of NC/TM distance ratio in terms of sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) for predicting difficult intubation in obese patient with Intubation difficulty…
- Trial name
- NCT05735106
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- KRL Hospital, Islamabad
Asa 1 and 2 Patients for Elective Surgery Requiring Caudal as Part of Their Care
The Effect of Caudal Volumes on the Anatomical Spread of Caudals in Children
Radiological study into the anatomical spread of caudal local anaesthetic in children age 1-7
- Trial name
- NCT00232921
- Testing
- caudal volume 1, caudal volume 2, caudal volume 3
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Prostate Cancer, Urinary Bladder Cancer
Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients
There is an increasing trend in the use of robotic-assisted radical prostatectomy or cystectomy (RARPC). Preventing lung atelectasis without inducing overdistention of the lung is challenging.
- Conditions
- Prostate Cancer, Urinary Bladder Cancer, Surgery, Positive End Expiratory Pressure
- Trial name
- NCT06307704
- Testing
- Lung Ultrasound - guided Stepwise PEEP, Standard Ventilation Protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Nazmy Edward Seif
LMA Vs I Gel
Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.
Invistigators study both supraglottic airway devices; the classic LMA and the I GEL mask are satisfactory devices providing high airway leaking pressures.
- Trial name
- NCT03843827
- Testing
- Laryngeal Mask Airway, I gel Airway
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
General Anesthesia, Laparotomy
Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy
The effects of anesthesia and surgery can lead to stress responses that result in hormonal and metabolic changes in the body. The immune system and the nervous system communicate both ways, and it was found that nociception and…
- Conditions
- General Anesthesia, Laparotomy, Inflammation
- Trial name
- PRO-Ketamine (NCT04462094)
- Testing
- Ketamine 0.3 mg/kg at end-of-surgery, Ketamine 0.3 mg/kg at anesthesia induction
- Where
- Indonesia
- Volunteers
- 68 people
- Sponsor
- Udayana University
Postoperative Ileus, Colorectal Surgery
Prucalopride in Postoperative Ileus
Postoperative ileus (POI) refers to the period of gut dysmotility that occurs after abdominal surgery. Patients with POI are unable to eat, suffer ongoing nausea and vomiting, are unable to open their bowels and have a prolonged…
- Conditions
- Postoperative Ileus, Colorectal Surgery, Postoperative Complications
- Trial name
- NCT02947269
- Testing
- Prucalopride
- Where
- New Zealand
- Volunteers
- 150 people
- Sponsor
- University of Auckland, New Zealand
Acute Pain
Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery
This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.
- Trial name
- Rectus (NCT03725527)
- Testing
- Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hemophilia
Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII)…
- Trial name
- SCOPE HIM (NCT05695391)
- Testing
- Coagulation Factor VIIa (Recombinant)
- Where
- 15 sites in United States, Malaysia and 4 more
- Volunteers
- 2 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Anaesthesia, General, Anesthesia, Intravenous
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing…
- Conditions
- Anaesthesia, General, Anesthesia, Intravenous, Ventilation
- Trial name
- NCT02706431
- Testing
- Hyperventilation
- Volunteers
- 31 people
- Sponsor
- Karolinska University Hospital