Clinical trials: Elective Operation Patients
Acute Kidney Dysfunction
Cardiopulmonary-bypass and Reno-protective Effect of Atorvastatin Trial
Acute kidney dysfunction is common after cardiac surgery. While many patients suffer no long-term ill effects from post-operative kidney dysfunction, some require initiation of dialysis therapy that can contribute to long-term…
- Trial name
- CREAT (NCT00910221)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Austin Health
Anesthesia, Neuromuscular Blockade
Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients
The train-of-four (TOF) ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures.
- Trial name
- NCT06467448
- Testing
- EMG Assessement of Recovery of Neuromuscular Function
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Mental Impairment, Complication
Impact and Burden of Postponing Elective Surgeries
Overall, little is known about the effects and burdens of postponed operations in patients with urological diseases. To investigate the consequences and develop possible strategies for overcoming these challenges, the…
- Trial name
- NCT06067373
- Testing
- questionnaire
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Graz
Effect of Dabigatran in Laboratory Coagulation Parameters
Effect of Dabigatran on Coagulation parameters-an ex Vivo Study
Dabigatran represent a new class of promising anticoagulation agents. As an oral direct thrombin inhibitor it has been effective in preventing venous thromboembolism in patients undergoing elective orthopaedic surgery.
- Trial name
- NCT01112202
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Cardiac Surgery, Prehabilitation
Prehabilitation Program for Patients Awaiting Elective Heart Surgery at Increased Risk of Postoperative Complications: Feasibility and Potential Clinical Outcomes
The goal of this study is to learn if an exercise-based prehabilitation program can help people who are waiting for heart surgery and are at higher risk of complications recover better.
- Conditions
- Cardiac Surgery, Prehabilitation, Postoperative Complications
- Trial name
- PRÉAD-CARDIAQU (NCT07144722)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Montreal Heart Institute
Elective Surgical Patients, Blood Pressure
Gabapentin and Pressor Response to Intubation
This study evaluates the effectiveness of oral gabapentin in reducing the pressor response (increased MAP, HR, and BP) during laryngoscopic intubation.
- Trial name
- NCT06705101
- Testing
- Gabapentin Group (Group G): Patients will receive 300 mg of oral Gabapentin
- Volunteers
- 144 people
- Sponsor
- Liaquat National Hospital & Medical College
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Pharmacological Action
The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.
In this randomized double blind placebo controlled study of tranexamic acid during minor spinal surgery, mean postoperative blood loss in the patients who received TXA was statistically significantly lower compared to placebo.
- Trial name
- NCT03714360
- Testing
- Tranexamic Acid, Sodium Chloride 0,9%
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Mikkel Østerheden Andersen
Patients Eligible for Elective Lower Extremity Femoral Nerve Surgery, Knee Arthroscopic Surgery
Clinical Observation of Bupivacaine Liposome for Lower Extremity Nerve Block
This prospective, sequential dose-finding clinical observational study aims to estimate the median effective concentration (EC50) and the 95% effective concentration (EC95) of liposomal bupivacaine for ultrasound-guided femoral…
- Trial name
- NCT07366905
- Testing
- Liposomal bupivacaine, 266mg
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Hainan Medical College
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Mobile Application, Preoperative Period
Utility of Preanestes@s2.0, a Web Based Application for Preoperative Assessment.
The use of web based self-assessment questionnaires as a complementary tool for conducting preoperative assessment (POA) is gaining increasing acceptance.
- Conditions
- Mobile Application, Preoperative Period, Internet-based Intervention, Surgical Procedures, Elective
- Trial name
- Preanestes@s (NCT06602310)
- Testing
- Web based preoperative assessment
- Where
- 2 sites in Spain
- Volunteers
- 2,254 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cataract
Effect of Surgical Planning Prompts on Elective Surgery Acceptance Rate
This randomized, double-blind, controlled trial investigates whether prompting patients facing elective cataract surgery to articulate their specific conditions for choosing surgery (a structured self-reflection intervention…
- Trial name
- NCT07544641
- Testing
- Structured Surgical Planning Self-Reflection
- Volunteers
- 268 people
- Sponsor
- Tongji University
Geriatrics, Hypotension on Induction
Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery
In this observational study, we will assess cFT by Carotid ultrasound and IVC collapsibility index for prediction of hypotension after induction of general anesthesia in geriatric patients undergoing elective surgery.
- Conditions
- Geriatrics, Hypotension on Induction, General Anesthetic Drug Adverse Reaction, Elective Surgery
- Trial name
- NCT06814054
- Testing
- Carotid Artery Corrected Flow Time measurement, Inferior vena cava collapsibility index
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Tanta University
Thrombosis, Hip Replacement
A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery
This study is to assess if DU176b is effective in prevention of blood clots following hip replacement surgery. The duration is 7-10 days of treatment and 30 and 60 day follow-up visits.
- Trial name
- NCT00398216
- Testing
- DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor
- Where
- 29 sites in United States, Canada and 5 more
- Volunteers
- 903 people
- Sponsor
- Daiichi Sankyo
Postoperative Nausea and Vomiting
Drug and Dose Adjustment in Preventing Postoperative Nausea and Vomiting
The aim is to evaluate the effectiveness of different regimens of prophylactic Ondansetron, Dexamethasone, or both, on the incidence and severity of post-operative nausea and vomiting.
- Trial name
- NCT04719741
- Testing
- Parallel Assignment
- Where
- Jordan
- Volunteers
- 1,000 people
- Sponsor
- Jordan Hospital
Colorectal Surgery
Pre-Surgical Immunonutrition's Effect on Colorectal Surgery
Colorectal surgery patients face excessive catabolism, increasing inflammation and immune compromise. The administration of nutritional supplements known as immunonutrition before gastrointestinal surgery has been shown to…
- Trial name
- NCT06883422
- Testing
- Preoperative oral immunonutrition formula, Preoperative oral Isocaloric and isoproteic polymeric formula
- Where
- Mexico
- Volunteers
- 126 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Nutrition Assessment, Nutritional Support
The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes
It is a study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation.
- Conditions
- Nutrition Assessment, Nutritional Support, Clinical Outcomes, General Surgery
- Trial name
- PNAS (NCT03115931)
- Testing
- no intervention
- Where
- China
- Volunteers
- 4,880 people
- Sponsor
- Jinling Hospital, China
Frailty in Adult Surgery, Frailty Syndrome
Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes
Frailty is a common geriatric syndrome defined as a clinical state of decreased physiologic reserve resulting in increased vulnerability to stressors.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgery
- Trial name
- NCT07367828
- Testing
- Intermediate/major elective surgery
- Where
- Iceland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven