Clinical trials: Elective Operation Patients
General Anesthesia
Echocardiographic Findings and 30-days Outcomes for Intraventricular Conduction Delay in Patients Undergoing Elective Surgeries
The purpose of this study is to investigate the type of the cardiac disease using transthoracic echocardiography in patients whose preoperative electrocardiography shows the intraventricular conduction delay.
- Trial name
- NCT02718313
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Hemodynamic Instability, Hypovolemia
Preoperative Volume Substitution in Elective Surgery Patients
Preoperative fasting can evoke a hypovolemia which may cause a hemodynamic instability during introduction of anesthesia. The purpose of this study is to test the hypothesis that a defined preoperative volume substitution…
- Conditions
- Hemodynamic Instability, Hypovolemia, Anesthesia
- Trial name
- NCT01811966
- Testing
- Volume, Control
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Philipps University Marburg
Diabetes Mellitus, Type 2
Pre-operative Carbohydrate Loading Patients With Diabetes Undergoing Elective Colorectal Surgery
Goal to evaluate the feasibility of conducting a large study that would assess the safety of carbohydrate drinks (i.e. juice) prior to elective colorectal surgery in patients with type 2 diabetes.
- Trial name
- NCT04495114
- Testing
- 40g carbohydrate load (Apple juice)
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of Alberta
Elective Cardiac Surgical Patients
Ventilatory Strategies After Cardiopulmonary Bypass Evaluated by Electrical Impedance Tomography
Pulmonary complications after cardiac surgeries are common. It is one of the most crucial concerns of cardiac surgeons and anesthesiologists.
- Trial name
- NCT04813250
- Testing
- ventilation mode setting
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Defense Medical Center, Taiwan
Hemorrhage
Pre-emptive Hemodynamic Optimization of High Risk Patients Undergoing Elective Major Surgical Procedures
Several recent clinical trials have documented that early aggressive resuscitation approached guided by defined hemodynamic variables using thoughtful protocols may improve outcome.
- Trial name
- NCT00725972
- Testing
- Augment O2 Delivery by hemodynamic protocol, High Risk Surgery
- Where
- United States
- Sponsor
- University of Pittsburgh
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery
The purpose of this study is to examine the superiority of YM150 to the placebo and to evaluate the dose-dependent response of YM150 in patients undergoing elective total hip replacement surgery.
- Trial name
- NCT00913120
- Testing
- YM150, Enoxaparin
- Where
- 16 sites in Japan, South Korea and 2 more
- Volunteers
- 610 people
- Sponsor
- Astellas Pharma Inc
Elective Thoracic Surgery, Pulmonary Function
Deep Learning for Preoperative Pulmonary Assessment in Thoracic CT
The trial was designed as a single-centre, non-interventional prospective observational study to utilize deep learning technology combined with computed tomography (CT) images to precisely predict the pulmonary function…
- Conditions
- Elective Thoracic Surgery, Pulmonary Function, Deep Learning
- Trial name
- NCT06477458
- Testing
- Single inspiratory phase computed tomography., Respiratory dual-phase computed tomography.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Elective Surgery, Target Controlled Infusion (TCI)
EC50 of Ciprofol Combined With Remifentanil for Inhibiting Tracheal Responses in Patients Undergoing Gynecological Surgery: a Two-phase Up-and-down Sequential Allocation Study
1. The combined induction of intubation with propofol and remifentanil is widely used in clinical anesthesia, primarily through a single intravenous injection.
- Conditions
- Elective Surgery, Target Controlled Infusion (TCI), Noxious Stimuli, Tracheal Intubation Stimulation
- Trial name
- EC50 via TCI (NCT07462949)
- Testing
- Cipofol combined with remifentanil administered via target-controlled infusion
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Desflurane, Propofol
Desflurane and Postoperative Sleep Quality in Patients Undergoing Elective Breast Surgery
This study intends to investigate the effects of desflurane on postoperative sleep quality to guide perioperative patient management.
- Conditions
- Desflurane, Propofol, Postoperative Sleep, PSQI
- Trial name
- NCT04805775
- Testing
- Desflurane Inhalation
- Where
- China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Chronic Post-operative Pain
Palmitoylethanolamide for Post-operative Pain Prevention
Postsurgical pain becomes chronic when it lasts more then two months after surgery. A neurogenic or neuropathic pathogenesis is hypothesized for this event that reaches high rates after urologic and gynecologic surgeries.
- Trial name
- PEAforCPSP (NCT01491191)
- Testing
- Palmitoylethanolamide
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Myocardial Ischemia, Critical Illness
Bright Light Exposure in Surgical Patients
1. Elucidate the influence of intense light therapy pretreatment in patients undergoing cardiac surgery. We hypothesize that intense light exposure is associated with the peripheral stabilization of Per2 in human buccal swabs and…
- Conditions
- Myocardial Ischemia, Critical Illness, Endothelial Dysfunction
- Trial name
- NCT03822949
- Testing
- Day Light, ICU Intense Light
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Colorado, Denver
This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections
A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients
This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery.
- Trial name
- NCT07562776
- Testing
- Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines., Standard pre operative fasting
- Volunteers
- 144 people
- Sponsor
- Gulab Devi Hospital
Peripheral Vein Cannulation Guided by Ultrasound
Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
This study evaluates two different techniques for peripheral venous cannulation in operating theatre. Ultrasound guided insertion of peripheral cannula in comparison with conventional approach without any ultrasound guidance.
- Trial name
- NCT05119985
- Testing
- Peripheral vein cannulation, Cannulation without ultrasound
- Where
- Czechia
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Cervical Spine Instability
Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
This study was done to compare the ease of tracheal intubation using the conventional C blade and the D blade of CMAC videolaryngoscope in patients undergoing cervical spine surgery.
- Trial name
- NCT05561231
- Testing
- Intubation with C blade, Intubation with D blade
- Where
- India
- Volunteers
- 68 people
- Sponsor
- King Edward Memorial Hospital, Mumbai
Cancer of Colon, Cancer of Rectum
Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery
To determine whether exercise and nutrition prehabilitation improves patient outcomes after cancer surgery
- Conditions
- Cancer of Colon, Cancer of Rectum, Liver Metastases
- Trial name
- SPECS (NCT04880772)
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Thrombocytopenia
Lusutrombopag Combined With Recombinant Human Thrombopoietin for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Destined to Undergo Elective Invasive Surgery
To assess the efficacy and safety of lusutrombopag combined with recombinant human thrombopoietin for the treatment of thrombocytopenia in patients with chronic liver disease destined to undergo elective invasive surgery.
- Trial name
- NCT06673498
- Testing
- Lusutrombopag combined with recombinant human thrombopoietin
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Anhui Provincial Hospital
the Position of Laryngeal Mask Airway
Comparison Between Blind And Ultrasound Guided Laryngeal Mask Airway Insertion
The Proper position of a laryngeal mask airway (LMA) requires confirmation to ensure the adequacy of laryngeal seal and pulmonary ventilation.
- Trial name
- NCT04090944
- Testing
- the fiberoptic laryngoscope (KARL STORZ 11301BN1, Germany) for confirmation of LMA position
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Beni-Suef University
Delirium, Postoperative
Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients
Postoperative agitation (hyperactive delirium) is common following major surgery(incidence was about 20% in our pilot study). Dexmedetomidine was related to a reduced delirium rate when comparing with midazolam in many clinical…
- Trial name
- NCT01283412
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Heart Diseases
Carbohydrate Loading on Insulin Resistance in Open Heart Surgery
This study is a single-blind randomized clinical trial involving 40 adult patients undergoing elective open-heart surgery. The sample was allocated into two groups: 20 subjects in the oral carbohydrate fluid group and 20 subjects…
- Trial name
- NCT06901947
- Testing
- Glucose drink
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia