Clinical trials: Elective Operation Patients
Preoperative Anxiety Experienced by the Pediatric Patient, Preoperative Anxiety
Comparing Two Doses of Midazolam With Added Dexmedetomidine for Kids Before Surgery
The goal of this randomized controlled trial is to investigate if adding intranasal dexmedetomidine to two different doses of intranasal midazolam provides effective sedation with fewer side effects in pediatric patients aged 1…
- Trial name
- NCT06979791
- Testing
- Dexmedetomidine + Midazolam 0.4 mg/kg, Dexmedetomidine + Midazolam 0.2 mg/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hypovolaemia Due to Acute Blood Loss
Safety and Efficacy of 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Patients Undergoing Elective Abdominal Surgery
The aim of the study is to investigate the safety of a 6% HES (Hydroxyethyl Starch) solution (Volulyte 6%) versus an electrolyte solution (Ionolyte) in patients undergoing elective abdominal surgery.
- Trial name
- PHOENICS (NCT03278548)
- Testing
- Volulyte 6%, Ionolyte
- Where
- 61 sites in Austria, Belgium and 8 more
- Volunteers
- 2,289 people
- Sponsor
- Fresenius Kabi
Ileostomy - Stoma, Colorectal Surgery
Readmission and Dehydration Prevention in Patients With Elective Ileostomy
The goal of this prospective observational study is to evaluate the adherence to DRIP score calculation and the application rate of each proposed item to prevent dehydration and readmission in patients undergoing ileostomy…
- Conditions
- Ileostomy - Stoma, Colorectal Surgery, Dehydration
- Trial name
- PREDESTO (NCT06824623)
- Where
- 7 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Multidisciplinary Italian Study group for STOmas (MISSTO)
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery
The primary objective was to demonstrate the dose-response of Semuloparin sodium (AVE5026) for the prevention of Venous Thromboembolism [VTE] in patients undergoing total knee replacement [TKR] surgery.
- Trial name
- TREK (NCT00331838)
- Testing
- Semuloparin sodium, Enoxaparin sodium
- Where
- 19 sites in Argentina, Bulgaria and 17 more
- Volunteers
- 705 people
- Sponsor
- Sanofi
Colostomy, Hirschsprung Disease - Pull Through
Bowel Preparation in Elective Pediatric Colorectal Surgery
Infections after elective intestinal surgery remain a significant burden for patients and for the health care system. The cost of treating a single surgical site infection is estimated at approximately $27,000.
- Conditions
- Colostomy, Hirschsprung Disease - Pull Through, Necrotizing Enterocolitis, Inflammatory Bowel Diseases
- Trial name
- NCT03593252
- Testing
- Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral
- Volunteers
- 81 people
- Sponsor
- McMaster University
Parenteral Nutrition
Efficacy and Safety of a Fish Oil Containing Lipid Emulsion
The purpose of the study is to compare a fish oil containing lipid emulsion against a medium-chain/long-chain triglyceride (MCT/LCT) lipid emulsion in terms of their efficacy and safety during postoperative parenteral nutrition.
- Trial name
- NCT01176695
- Testing
- fish oil containing lipid emulsion, MCT/LCT containing lipid emulsion
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- B. Braun Melsungen AG
Frailty
Perioperative Prehabilitation on Markers of Fitness and Frailty in Patients Undergoing Elective Surgery
A growing body of evidence suggests that patients who receive good perioperative care (i.e. care prior to surgery, during surgery, and after surgery) tend to have fewer complications, quicker recovery times, and shorter hospital…
- Trial name
- NCT05977556
- Testing
- Combined neuromuscular exercise training and 'sit less, move more' program
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Blood Loss, Surgical, Postoperative Hemorrhage
Effect of Aprotinin on Transfusion Requirements in Patients Undergoing Elective Spinal Fusion Surgery
The objective of this study is to evaluate the safety and efficacy of aprotinin as compared to placebo, in reducing the need for blood transfusion in adult subjects undergoing elective spinal fusion surgery involving 3 to 7…
- Trial name
- NCT00327379
- Testing
- Trasylol (Aprotinin, BAYA0128)
- Where
- 14 sites in Canada, Germany and 1 more
- Volunteers
- 54 people
- Sponsor
- Bayer
Cervical Compression Myelopathy, Ischemia
Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery
The purpose of this study is to assess whether a large clinical trial testing the effect of RIPC on neurologic outcome in patients undergoing elective cervical decompression surge is warranted.
- Conditions
- Cervical Compression Myelopathy, Ischemia, Reperfusion Injury, Spinal Cord Injury
- Trial name
- NCT00778323
- Testing
- limb remote ischemic preconditioning (LRIPC)
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Xijing Hospital
Cardiovascular Diseases
Prehabilitation's Effect on Skeletal Muscle Mass in Cardiac Patients
The study will investigate the effect prehabilitation on skeletal muscle mass via a scanner.
- Trial name
- NCT06624774
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester Metropolitan University
Tracheal Intubation
Assessment of the the ETView Double-lumen Tube
The double tube ETView is particularly innovative as it includes an integrated optical fiber to visualize the carena. This study aims to verify if if its use avoids the requirement of a fibreoptic bronchoscopy.
- Trial name
- ETView1 (NCT02040961)
- Testing
- ETView Double-Lumen Tube
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Hopital Foch
Postoperative Pulmonary Complications (PPC)
Geriatric Nutritional Risk Index and ASA Status for Predicting Lung Complications After Major Abdominal Surgery in Older Adults
Postoperative pulmonary complications (PPCs), such as pneumonia, atelectasis, and respiratory failure, are major causes of illness, prolonged hospital stays, and intensive care admissions in older patients undergoing elective…
- Trial name
- NCT07862777
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Change; Retina
Optical Coherence Tomography (OCT) in Elderly Patients After Elective Orthopaedic Surgery
After obtaining informed consent each patient underwent OCT examination, usually one day before elective orthopaedic surgery (knee replacement). The OCT examination was repeated after the surgery.
- Trial name
- NCT04311801
- Testing
- Optical Coherence Tomography
- Volunteers
- 30 people
- Sponsor
- Masaryk Hospital Usti nad Labem
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Venous Thromboembolism
BIBR 1048 in the Prevention of Venous Thromboembolism in Patients Undergoing Primary Elective Total Hip Replacement Surgery
To determine the therapeutic window of BIBR 1048 in order to select doses for further studies in the development plan. Twice daily regimen will be tested for most dose levels and once daily administration will also be evaluated…
- Trial name
- NCT02170701
- Testing
- BIBR 1048
- Volunteers
- 289 people
- Sponsor
- Boehringer Ingelheim
Staphylococcal Infections
Preoperative Nasal Swabs From Pediatric Patients
We intend to take a nasal swab from each pediatric pre-operative patient in our out-clinic with the intention of looking for a connection between positive operative incisions and a positive nasal swab.
- Trial name
- NCT00646919
- Testing
- Nose swab
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Patients Ongoing Elective Abdominal Laparoscopy
Laparoscopic Surgery and Abdominal Compliance
The objective of the study is to describe factors influencing abdominal compliance during laparoscopic surgery, including neuromuscular blocking agents (NMBA).
- Trial name
- COELIOCUR (NCT02816567)
- Testing
- propofol, NMBA - cisatracurium, sufentanil
- Where
- France
- Volunteers
- 180 people
- Sponsor
- CHU de Reims
Coronary Artery Disease, Postoperative Pulmonary Complications
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Pulmonary atelectasis and loss of lung aeration are common complications following cardiac surgery with cardiopulmonary bypass (CPB) and are associated with impaired oxygenation and prolonged mechanical ventilation.
- Conditions
- Coronary Artery Disease, Postoperative Pulmonary Complications, Pulmonary Atelectasis, Postoperative, Diaphragm Dysfunction
- Trial name
- FCV-PCV-DTI-LU (NCT07800741)
- Testing
- Flow-Controlled Ventilation, Pressure-Controlled Ventilation (PCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery
The purpose of this study is to examine the superiority of YM150 to the placebo and to evaluate the dose-dependent response of YM150 in patients undergoing elective total knee replacement surgery.
- Trial name
- NCT00917254
- Testing
- YM150, Enoxaparin
- Where
- 13 sites in Japan, Taiwan and 1 more
- Volunteers
- 369 people
- Sponsor
- Astellas Pharma Inc
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany