Clinical trials: Elective Surgeries
Cesarean Section Complications
Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section
Purpose to evaluate the effects of sublingual misoprostol with or without intravenous tranexamic acid (TA) in comparison with placebo on reducing post-partum hemorrhage in pregnant women with twin pregnancy undergoing an elective…
- Trial name
- NCT03774524
- Testing
- Misoprostol, TA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Transfusion Related Complication
Restrictive Versus Liberal Transfusion, Major Surgeries
Investigators aimed to compare the restrictive and liberal blood transfusion methods applied in major surgical operations performed in Anesthesiology and Reanimation Clinic and investigate their effects on postoperative…
- Trial name
- transfusion (NCT03394274)
- Testing
- restrictive and liberal transfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 892 people
- Sponsor
- Leyla Kılınc
Post-operative Analgesia, Early Mobility
Comparison of the Combination of Popliteal Sciatic and Femoral Block With the Combination of Ipack Adductor Canal Blocks
Comparison of the combination of popliteal sciatic and femoral block with the combination of ipack adductor canal blocks and mobilization and analgesia duration in elective knee surgeries
- Trial name
- kneesurgery (NCT06683313)
- Testing
- combination femoral nerve and popliteal sciatica block, combination adductor canal and IPACK block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Surgery, Anesthesia; Functional
Effectiveness of Continous Adjuvant Lidocaine on General Anaesthesia on Tumor Craniotomy Surgery
This study aims to investigate the effect of adjuvant continuous lidocaine in General Anesthesia on Depth of Anesthesia (qCON), Pain Response (qNOX), and Blood Sugar Levels in Elective Primary Tumor Craniotomy Surgery
- Conditions
- Surgery, Anesthesia; Functional, Haemodynamic Instability
- Trial name
- NCT06249113
- Testing
- NaCl 0.9%, Adjuvant lidocaine continous
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Airway Complication of Anesthesia
Role of Airway Topicalization in Awake Fiberoptic Intubation
Airway management is an integral part of general anesthesia. Difficult airway management may lead to various adverse events such as airway trauma, up to cardiopulmonary arrest.
- Trial name
- NCT06720220
- Testing
- Dexmedetomidine Hydrochloride, Nebulization, Atomization
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Regional Anaesthesia in Cesarean Operations
Comparison of Dural Puncture Epidural and Standard Epidural Anesthesia Techniques in Elective Cesarean Deliveries
Neuraxial techniques are the most effective form of labor analgesia in contemporary obstetric anesthesia practice, predominantly through the use of epidural (EPL) and combined spinal-epidural (CSE) techniques.
- Trial name
- NCT07295080
- Testing
- Dural puncture epidural (DPE) anaesthesia, standart epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Uterine Atony With Hemorrhage
Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients
Postpartum hemorrhage remains a leading cause of maternal morbidity and mortality worldwide, even in high income countries. Uterine atony is estimated to cause 70-80% of postpartum hemorrhage.
- Trial name
- NCT03904446
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cynthia Wong
Post-Dural Puncture Headache
Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for Cesarean
Postdural puncture headache (PDPH) is a common complication after spinal anesthesia. The role of pregabalin and hydrocortisone in the treatment of PDPH is unclear.
- Trial name
- PDPH (NCT03910088)
- Testing
- Pregabalin 100Mg Oral Cap, Hydrocortisone, Acetaminophen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Complications; Cesarean Section
Control of Blood Loss During Caesarean Section
trial of 3 protocols to determine the best one to control blood loss during caesarean section
- Trial name
- NCT01412073
- Testing
- oxytocin, Misoprostol
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Elective Laproscopic Bilateral Inguinal Hernia, Elective Laproscopic Cholecystectomy
Controlled Release of Oxycodone 10 mg In Pre-Medication For The Post Operative Analgesia In Elective Laparoscopic Bilateral Inguinal Hernia And Elective Laparoscopic Cholecystectomy
A Prospective Double Blind RCT: Controlled Release Oxycodone 10 mg On a 12 h Dosing Schedule Started With The Premedication ,Placebo Controlled Study,On Post Operative Analgesia Management in Laparoscopic Cholecystectomy and…
- Trial name
- NCT00480142
- Testing
- Oxycodone 10 mg
- Volunteers
- 100 people
- Sponsor
- Kaplan Medical Center
Cesarean Section, Anesthesia, General
Comparing Inhalational Anesthesia and TIVA on Maternal and Neonatal Hemodynamics in Elective Cesarean Section
This prospective, double-blind, randomized controlled trial compares the effects of total intravenous anesthesia (TIVA) versus sevoflurane-based inhalational anesthesia on maternal hemodynamics, depth of anesthesia, and early…
- Conditions
- Cesarean Section, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- NCT07513870
- Testing
- Propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Medipol University
Anesthesia Induction
A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects
This is a multicenter, randomized, double-blind, etomidate-controlled phase III clinical trial. The primary objective is to compare the efficacy and safety between ET-26 and etomidate in the induction of general anesthesia in…
- Trial name
- NCT06203431
- Testing
- ET-26, Etomidate Injectable Emulsion
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Thoracic, Surgery
Non Invasive Cardiac Output Evaluation With Starling SV for Lung Elective Surgery
Intraoperative hemodynamic optimization decreases postoperative complications and length of stay in high risk patient. Therefore, continuous monitoring of cardiac output (Qc) is recommended to guide fluid management.
- Trial name
- NICOLE (NCT04251637)
- Testing
- Cardiac output monitoring with Starling SV.
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity
Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine
Neuraxial anesthesia, especially the subarachnoid block, is the preferred method for LSCS. The intrathecal spread of local anesthetic drugs is unpredictable.
- Conditions
- Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity, Cesarean Section Complications
- Trial name
- NCT04403724
- Testing
- Bupivacaine-fentanyl-Morphine.
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Assiut University
Surgical Procedures, Telemedicine
The Risk of Surgical Cancellation in Adult Patients Assessed by Telephone Versus In-person for Scheduled Non-cardiac Elective Surgery.
Telemedicine has been regulated in Colombia since 2006, with applications in anesthesia being explored since 2004 to improve accessibility and reduce costs.
- Conditions
- Surgical Procedures, Telemedicine, Preanesthetic Medication, Preoperative Care
- Trial name
- NCT06693869
- Where
- Colombia
- Volunteers
- 1,176 people
- Sponsor
- Universidad de Antioquia
Coronary Artery Disease
Predictive Value of Allen's Test Result in Elective Patients Undergoing Coronary Catheterization Through Radial Approach
The study will evaluate the feasibility and safety of radial approach in patients undergoing coronary catheterisation without any restrictions based on the results of Allen's test.
- Trial name
- RADAR (NCT00597324)
- Testing
- coronary catheterisation
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Marco Valgimigli
Respiratory Disorders, Intensive Care, Neonatal
Timing of Planned Caesarean Section and Morbidity of the Newborn
The caesarean section rate is rising globally. About 10% of the newborns are submitted to a neonatal department after planned caesarean section, primarily with respiratory disorders.
- Trial name
- NCT00835003
- Testing
- Elective caesarean section
- Where
- 7 sites in Denmark
- Volunteers
- 1,273 people
- Sponsor
- Aarhus University Hospital
Pain, Anxiety
The Effect of Jazz on Postoperative Pain and Stress in Patients Undergoing Elective Hysterectomy
The purpose of this study is to investigate the effects of music on patients after surgery in the Post Anesthesia Care Unit (PACU).
- Trial name
- NCT01834027
- Testing
- Jazz music, No music
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Milton S. Hershey Medical Center
Gastric Emptying, Pregnancy
Rate of Gastric Emptying in Term Parturients Undergoing Elective Cesarean Section
The aim of the study is to use sequential ultrasound evaluation of the gastric volume to determine how long it takes for the stomach of a fasting pregnant woman at term, admitted for elective cesarean section, to empty after…
- Trial name
- NCT03800251
- Testing
- Nutricia PreOp - a clear, non-carbonated, lemon flavoured, carbohydrate drink that provides 0.5kcal/ml
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Hypotension Symptomatic, Vasoconstriction
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the…
- Conditions
- Hypotension Symptomatic, Vasoconstriction, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- annie-zoe (NCT04404946)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Aretaieion University Hospital
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