Clinical trials: Elective Surgeries
Arthroplasty, Replacement, Hip, Anesthesia, Spinal
Goal Directed Fluid Therapy Versus Liberal Fluid Regimen in Primary Elective Hip Artrhoplasty
Patients undergoing elective primary total hip replacement and spinal anesthesia may encounter significant hemodynamic instability.
- Conditions
- Arthroplasty, Replacement, Hip, Anesthesia, Spinal, Hemodynamic Monitoring, Crystalloid Solutions
- Trial name
- NCT04996420
- Testing
- Clearsight non invasive hemodynamic monitoring
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Incision, Surgical, Cesarean Delivery Affecting Fetus
Tailored Pfannenstiel Incision for Caesarean Delivery According to the Fetal Head Occipitofrontal Diameter
The purpose of the study is whether the Pfannenstiel skin incision can be adjusted according to the occipitofrontal diameter (OFD) of the fetal head.
- Conditions
- Incision, Surgical, Cesarean Delivery Affecting Fetus, Pfannenstiel Incision Length, Fetal Occipitofrontal Diameter
- Trial name
- NCT05632796
- Testing
- Adjusting the Pfannenstiel skin incision according to the occipitofrontal diameter (OFD) of the fetal head.
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Venous Thromboembolism
Dose-confirmatory Bridging Study in Total Knee Replacement
The objective of this dose-confirmatory bridging study is to investigate the safety and efficacy of rivaroxaban 5 to 10 mg once-daily (od) dosing in the prevention of venous thromboembolism (VTE) in Japanese patients undergoing…
- Trial name
- NCT01206972
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 33 sites in Japan
- Volunteers
- 302 people
- Sponsor
- Bayer
Intra-abdominal Surgery
Stem Cells Found in the Abdominal Cavity in Humans
The purpose of this research study is to determine the genotype (genetic composition) and phenotype (physical appearance) of cells derived from the abdominal cavity to determine whether stem cells are present.
- Trial name
- NCT00576264
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cedars-Sinai Medical Center
Venous Thrombosis, Pulmonary Embolism
BMS-562247 in Subjects Undergoing Elective Total Knee Replacement Surgery
The purpose of this study is to learn if BMS-562247 can prevent blood clots in the legs and lungs in men and women following unilateral total knee replacement surgery. The safety of this treatment will also be studied.
- Trial name
- NCT00097357
- Testing
- Apixaban, Enoxaparin, Warfarin
- Where
- 147 sites in United States, Argentina and 7 more
- Volunteers
- 1,238 people
- Sponsor
- Bristol-Myers Squibb
Wrist Blood Pressure Measurements, Anesthesia Resulting in Shivering
Wrist NIBP During Elective Cesarean Delivery
Blood pressure is typically measured with a non-invasive cuff placed on the upper arm. This cuff cannot take accurate measurements when the patient's arm is moving.
- Trial name
- NCT01677234
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of British Columbia
Post Operative Nausea and Vomiting, Rescue Emetic Therapy
Rescue Emetic Therapy for Children Having Elective Surgery
To compare ondansetron, metoclopramide, diphenhydramine, and placebo in order to determine which anti-emetic is most efficacious as a "rescue therapy" for pediatric patients ages 3-18 who have post-operative vomiting after a…
- Trial name
- RETCHES (NCT01067677)
- Testing
- Metaclopramide, Ondansetron, diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Franklyn Cladis
Emergency Medical Services, Electric Countershock
A Feasibility Study for Elective Cardioversion of Atrial Fibrillation at Home
The goal of this pilot, non-controlled, non-randomised, single centre, prospective intervention feasibility study is to assess the feasibility of a home DC-ECV in the treatment of recurrent symptomatic AF performed by APP in 25…
- Trial name
- Electra-1 (NCT06322836)
- Testing
- Duble current electro cardioversion
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- RAV Brabant MWN
Nutrition Status
The Impact of Preoperative Nutrition Intervention on Muscle Mass Preserve in Older Adults Undergoing Elective Surgery
Sarcopenia-the progressive loss of muscle mass and strength-is a major clinical issue, especially in surgical patients with malignancy.
- Trial name
- NCT07262034
- Where
- Thailand
- Volunteers
- 62 people
- Sponsor
- Siriraj Hospital
Obstructive Sleep Apnea
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing
Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications.
- Trial name
- NCT03499132
- Testing
- anesthesia
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Assess the Periprocedural Myocardial Necrosis
ROsuvastatin Pretreatment to Reduce MyocArdial Periprocedural Necrosis:Comparison With Atorvastatin Reloading
An increase in cardiac biomarkers has been shown to occur in 5% to 30% of patients after otherwise successful percutaneous coronary interventions (PCIs)(1) Apart from side-branch occlusion, intimal dissection and coronary spasm…
- Trial name
- ROMAIIReload (NCT01228227)
- Testing
- ATORVASTATIN 80 mg, ROSUVASTATIN 40 mg
- Where
- Italy
- Volunteers
- 310 people
- Sponsor
- Gennaro Sardella
Post-Dural Puncture Headache
Intrathecal Neostigmine for Prevention of PDPH
Neuraxial blocks continue to be the cornerstone of anesthesia and postoperative analgesia for normal vaginal delivery and elective caesarean section due to its approved safety and efficiency for decades.
- Trial name
- NCT03587441
- Testing
- Neostigmine Methylsulfate, Dextrose 5% in water
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Fayoum University Hospital
Valve Heart Disease, Elective Cesarean Delivery
Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery
Rheumatic heart valve diseases are prevalent among the young people in Egypt secondary to the socioeconomic conditions. The goal of anesthetic management of these patients is maintenance of sinus rhythm, systemic blood pressure…
- Trial name
- NCT01571791
- Testing
- Ketorolac-Lidocaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Osteoporosis
GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients
The study is designed as a retrospective, single-center study for subjects previously treated with the AGN1 LOEP Kit. This will be a non-randomized and non-blinded study.
- Trial name
- NCT05966974
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- AgNovos Healthcare, LLC
Oesophageal Cancer
Does the Incremental Shuttle Walk Test Predict the Development of a Hospital Acquired Pneumonia in Patients Undergoing Elective Oesophagectomy: A Prospective Cohort Study
The purpose of this study was to assess the predictive value of the incremental shuttle walk test on rates of hospital acquired pneumonia for patients undergoing oesophagectomy.
- Trial name
- NCT04440124
- Testing
- Incremental shuttle walk test
- Where
- United Kingdom
- Volunteers
- 121 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Postoperative Delirium (POD), Abdominal Neoplasms
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
This prospective observational cohort study aims to investigate the relationship between perioperative endogenous melatonin levels and postoperative delirium in patients aged 65 years or older undergoing elective abdominal cancer…
- Trial name
- NCT07859488
- Testing
- Perioperative Biomarker Assessment, Confusion Assessment Method (CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatma Cigdem Ozakin
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications
Use Versus Non-use of Bladder Catheterization in Elective Cesarean Delivery
The goal of this randomized controlled trial is to investigate the impact of routine bladder catheterization in uncomplicated cesarean sections on time to ambulation, time to discharge, urinary retention, development of urinary…
- Trial name
- NCT06242756
- Testing
- Bladder catheterization
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Bolus Maintenance in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07404579
- Testing
- HRS-9190, Rocuronium
- Where
- 2 sites in China
- Volunteers
- 103 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Postoperative Recovery, Anesthesia, General
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
This randomized controlled trial evaluates postoperative quality of recovery assessed with the Quality of Recovery-15 questionnaire in adult patients undergoing elective major urological surgery under opioid-free versus…
- Conditions
- Postoperative Recovery, Anesthesia, General, Analgesics, Opioid, Urologic Surgical Procedure
- Trial name
- QoR-OFA-URO (NCT07665463)
- Testing
- Remifentanil-based general anesthesia, Opioid-free general anesthesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
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