Clinical trials: Elective Surgical Patients
Arthroplasty, Replacement, Prevention of Venous Thromboembolism
Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate
To supplement the current evidence of the effect of Pradaxa® (dabigatran etexilate) on coagulation parameters, including a calibrated thrombin time test, in patients with moderate renal impairment undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Prevention of Venous Thromboembolism, Moderate Renal Impairment (CrCl 30-50 mL/Min)
- Trial name
- NCT01184989
- Testing
- Dabigatran etexilate
- Where
- 10 sites in Austria, Canada and 4 more
- Volunteers
- 142 people
- Sponsor
- Boehringer Ingelheim
Emergence Delirium, Anesthesia
Emergence Delirium、fBFI-ENO Score (Extraversion + Neuroticism - Openness) Based on the Fast Big Five Personality Scale-10、An Adult Patient With ASAI-III Who is Scheduled for Elective Non-cardiac Surgery and is to Undergo General Anesthesia With Tracheal Intubation
The aim of this study is to verify the generalizability of the fBFI-ENO score (extraversion + neuroticism - openness) constructed based on the Rapid Big Five Personality Scale - 10 across different genders, ages, and surgical…
- Trial name
- NCT07775768
- Volunteers
- 880 people
- Sponsor
- Hongjiao Xu
Difficult / Failed Intubation
NC/TMD Ratio As a Difficult Airway Predictor in Obese Patients
To assess accuracy of NC/TM distance ratio in terms of sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) for predicting difficult intubation in obese patient with Intubation difficulty…
- Trial name
- NCT05735106
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- KRL Hospital, Islamabad
Cholecystectomy, Elective Surgery
Comparison Of Dexmedetomidine and Fentanyl In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy.
Compare effects of intravenous dexmedetomidine and fentanyl in attenuation of intubation response in a patient undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04089592
- Testing
- Dexmedetomidine, Fentanyl
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Elective Surgical Procedure
Perioperative Management & Outcome Following Preoperative Transthoracic Echocardiography in Noncardiac Surgery Patients
In August 2022 the European Society of Cardiology published updated guidelines including recommendations on preoperative transthoracic echocardiography.
- Trial name
- NCT06409234
- Testing
- Transthoracic Echocardiography Recieved
- Where
- Germany
- Volunteers
- 8,250 people
- Sponsor
- European Society of Anaesthesiology
Coronary (Artery); Disease, Aortic Valve Stenosis
Preventive Heart Rehabilitation to Prevent Complications in Patients Undergoing Elective Open Heart Surgery
Rationale: Patients undergoing cardiac surgery are at risk of developing perioperative complications and major adverse cardiac events, mainly related to both their preoperative status and type of surgical procedure.
- Conditions
- Coronary (Artery); Disease, Aortic Valve Stenosis, Cardiac Surgery
- Trial name
- Heart-ROCQ (NCT02984449)
- Testing
- Pre+post-operative Cardiac rehabilitation, Postoperative Cardiac rehabilitation
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- University Medical Center Groningen
PERIPHERAL VASCULAR DISEASES, Digestive Diseases
Evaluation of Surgical Risk in Elderly Patients Submitted to Elective Surgery
The purpose of this study is to establish the surgical risk factors and differences between different diseases in elderly patients submitted to elective surgery in our institution.
- Conditions
- PERIPHERAL VASCULAR DISEASES, Digestive Diseases, BILIARY TRACT DISEASES
- Trial name
- NCT00672698
- Testing
- SURGERY
- Where
- Chile
- Sponsor
- Cirujanos la Serena
Perioperative Anxiety, Perioperative Stress
Effect of Virtual Reality on Anxiety, Stress, and Patient's Satisfaction Among Patients Undergoing Regional Anesthesia
The goal of this clinical trial was to investigate the effect of Virtual Reality (VR) on intraoperative anxiety, stress, and patient satisfaction among Palestinian patients undergoing regional anesthesia.
- Conditions
- Perioperative Anxiety, Perioperative Stress, Patient Satisfaction, Regional Anesthesia
- Trial name
- VR (NCT07132216)
- Testing
- Meta Quest 2 VR headset
- Where
- Palestinian Territories
- Volunteers
- 150 people
- Sponsor
- Cairo University
Hyperlactatemia, Brain Tumor
Hyperlactatemia During and After Tumorcraniotomy
This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy.
- Conditions
- Hyperlactatemia, Brain Tumor, Surgery, Anesthesia
- Trial name
- NCT04410315
- Testing
- Serum-lactate < 2,2 mmol/L, Serum-lactate >/= 2,2 mmol/L
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Patients Undergoing Elective Thoracic Surgery Requiring Obligatory Single-lung Ventilation During Surgery
Prospective, Randomized Clinical Trial Evaluating the ETView Double-Lumen Tube
No prospective randomized clinical trial assessed the performance of this new device in a clinical setting. Consequently the aim of this study is to determine clinical performance of this new device compared with conventional…
- Trial name
- NCT01807676
- Testing
- ET View Double Lumen Tube, conventional Double Lumen Tube
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Venous Thromboembolism
Pharmacokinetic (PK) Assessment of BIBR 1048 in Patients After Primary Elective Total Hip Replacement Surgery
To determine the PK profile of a single dose 150 mg BIBR 1048, oral capsule, administered 1-3 hours post surgery in hip replacement patients.
- Trial name
- NCT02170935
- Testing
- BIBR 1048 capsule
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
Elective Treatment Rates and Surgical Non-eligibility Among Men and Women With Intact Abdominal Aortic Aneurysms
The overall aim is to determine the frequency by which women and men with intact abdominal aortic aneurysms (AAA) are treated with elective surgery at three vascular outpatient clinics in Europe, and to investigate whether the…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Aneurysm, Aortic Aneurysm
- Trial name
- NCT05346289
- Testing
- Elective surgery for intact AAA
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Gastric Cancer
Safety of 250ml Preoperative Carbohydrate Drink in Gastric Cancer Patients
This study aims to assess the impact of preoperative oral carbohydrate drink on gastric emptying and PH of gastric fluid in gastric cancer patients directly.
- Trial name
- NCT02815150
- Testing
- preoperative oral carbohydrate drink
- Where
- China
- Volunteers
- 88 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Desflurane, Propofol
Desflurane and Postoperative Sleep Quality in Patients Undergoing Elective Breast Surgery
This study intends to investigate the effects of desflurane on postoperative sleep quality to guide perioperative patient management.
- Conditions
- Desflurane, Propofol, Postoperative Sleep, PSQI
- Trial name
- NCT04805775
- Testing
- Desflurane Inhalation
- Where
- China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Inguinal Hernia, Quality of Life
Objective and Perceived Quality Study in Patients Undergoing Elective Groin Hernia Surgery
This is a prospective non-comparative observational study of cohorts. Consists on offering surveys to every patient undergoing groin hernia surgery in our Abdominal Wall Surgery Unit, in Hospital of Navarra.
- Conditions
- Inguinal Hernia, Quality of Life, Surgery, Survey
- Trial name
- NCT03860285
- Testing
- Short form 36 quality of life survey
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Intensive Care, Surgical
Postoperative Delirium in Adult Patients After Elective Craniotomy Under General Anaesthesia
Postoperative delirium may result in many adverse complications. At present little is known about postoperative delirium in patients after crniotomy because they may manifest similar symptoms to definitely delirium for some…
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT03087838
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Capital Medical University
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Rectal Cancer
The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery
Patients' ability to tolerate surgery is associated with physical fitness: less fit patients have an increased rate of death and serious complications following major surgery.
- Trial name
- SRETP (NCT01914068)
- Testing
- Supervised exercise in hospital
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill