Clinical trials: Elective Surgical Procedures, active
Gastric Emptying, Caesarean Delivery
Comparison of 'Sip Til Send' Regimens Prior to Elective Caesarean Delivery Using Bedside Gastric Ultrasound
'Sip Til send' is a liberal drinking policy that replaces fasting before a caesarean delivery, meaning that women waiting in hospital can freely drink sips of water until they are called from the ward for their delivery.
- Conditions
- Gastric Emptying, Caesarean Delivery, Pregnancy
- Trial name
- NCT07407530
- Testing
- The carbohydrate group represent the interventional group and will utilise the standard carbohydrate-rich drink, The "water group"
- Where
- 2 sites in Ireland
- Volunteers
- 190 people
- Sponsor
- The Rotunda Hospital
Squamous Cell Carcinoma of the Oropharynx
p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT)
Volume and Dose De-Intensified Radiotherapy for p16+ Squamous Cell Carcinoma of the Oropharynx: A Multi-Centre, Single Arm Prospective Cohort Study
- Trial name
- PROTEcT (NCT04104945)
- Testing
- De-intensified chemoradiotherapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- AHS Cancer Control Alberta
Intraoperative Pain
Sensory Stimuli During Cesarean Delivery
During a cesarean delivery (C-section), most patients are awake and receive spinal or epidural anesthesia to block pain from the lower body.
- Trial name
- PIONEER-MC (NCT07340970)
- Testing
- Patient-initiated request for pharmacological intervention during cesarean delivery
- Where
- Canada
- Volunteers
- 1,005 people
- Sponsor
- University of British Columbia
Abdominal Aortic Aneurysms
Physician Modified Endovascular Grafts
The primary objectives of this study are to determine whether physician modified endovascular grafts (PMEG) and specified company manufactured investigational devices are a safe and effective method of treating patients with…
- Trial name
- PMEG (NCT01538056)
- Testing
- Fenestrated Endovascular Graft or Company Manufactured Terumo Aortic Fenestrated TREO Endovascular Graft
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Washington
Cancer of the Head and Neck, Oropharynx Cancer
Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer
This trial will explore giving standard dose chemotherapy and radiation therapy to sites of disease including all lymph nodes involved with HPV-positive oropharyngeal cancer, but administer lower doses of radiation therapy to the…
- Conditions
- Cancer of the Head and Neck, Oropharynx Cancer, HPV Positive Oropharyngeal Squamous Cell Carcinoma, Throat Carcinoma
- Trial name
- ENID (NCT04444869)
- Testing
- Cisplatin injection
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Missouri-Columbia
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Postoperative Delirium (POD), Abdominal Neoplasms
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
This prospective observational cohort study aims to investigate the relationship between perioperative endogenous melatonin levels and postoperative delirium in patients aged 65 years or older undergoing elective abdominal cancer…
- Trial name
- NCT07859488
- Testing
- Perioperative Biomarker Assessment, Confusion Assessment Method (CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatma Cigdem Ozakin
Minimally Invasive Coronary Revascularization Surgery, Elective Surgery
Impact of Total Coronary Revascularization Via Left Anterior Thoracotomy (TCRAT) vs. Robotic-Assisted Harvesting of LIMA (ITcrats)
The two types of total coronary revascularization via left anterior thoracotomy (TCRAT) might have their potential benefits and disadvantages.
- Trial name
- ITcrats (NCT06988735)
- Testing
- Nonrobotic TCRAT, Robotic TCRAT
- Where
- Saudi Arabia
- Volunteers
- 182 people
- Sponsor
- Mohamed R El Tahan
Oropharyngeal Squamous Cell Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma
Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma
This is a single-arm, phase II study that is designed to investigate nodal and primary tumor CTV dose de-escalation (30 Gy) in HPV positive oropharyngeal cancer.
- Trial name
- REDUCE-30 (NCT07497607)
- Testing
- Cisplatin, Radiotherapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Sara Medek
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Coronary Arterial Disease (CAD), Radial Artery Spasm
Impact of Preprocedural Stress Ball Use on Radial Artery Outcomes in Elective Coronary Angiography
This randomized, double-blind, controlled trial aims to evaluate the effect of preprocedural hand exercise using a stress ball on the incidence of radial artery spasm and other vascular complications in patients undergoing…
- Conditions
- Coronary Arterial Disease (CAD), Radial Artery Spasm, Radial Artery Occlusion, Transradial Angiogram
- Trial name
- SPARROW (NCT07087522)
- Testing
- Stress Ball Use
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Sakarya University
Renal Perfusion, Minimally Invasive Surgical Procedures
Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery
This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery.
- Conditions
- Renal Perfusion, Minimally Invasive Surgical Procedures, Acute Kidney Injury
- Trial name
- RRI-NIRS (NCT07635160)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain, Emergence Delirium
Effect of Preoperative Fasting Duration on Postoperative Pain and Emergence Agitation in Pediatric Patients Undergoing Urogenital Surgery
This study aims to evaluate the effect of preoperative fasting duration on postoperative pain and emergence agitation in pediatric patients undergoing urogenital surgery.
- Conditions
- Postoperative Pain, Emergence Delirium, Emergence Agitation
- Trial name
- NCT07552259
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Nutrition Status
The Impact of Preoperative Nutrition Intervention on Muscle Mass Preserve in Older Adults Undergoing Elective Surgery
Sarcopenia-the progressive loss of muscle mass and strength-is a major clinical issue, especially in surgical patients with malignancy.
- Trial name
- NCT07262034
- Where
- Thailand
- Volunteers
- 62 people
- Sponsor
- Siriraj Hospital
Pain, Postoperative
Screen Addiction and Postoperative Pain
Excessive or problematic smartphone use has become increasingly common and has been associated with various psychological and physical health consequences, including anxiety, depressive symptoms, reduced sleep quality…
- Trial name
- NCT07242872
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Congenital Lung Malformations
Respiratory and Psychological Impact of Elective Surgery of Congenital Lung Malformations
The absence of surgery of Congenital lung malformations (CLMs), if it avoids a stressfull event, is accompanied by a "medicalization" of the child, which will be regularly followed up in a specialized medical and surgical…
- Trial name
- MALFPULM2 (NCT06424392)
- Testing
- General Health Questionnaire (GHQ-12), State-Trait Anxiety Inventory (STAI-Y), Revised Children's Manifest Anxiety Scale (RCMAS)
- Where
- France
- Volunteers
- 434 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oncologic Disease, Urgent Surgery
Dynamic Postoperative Trends for Early Detection of Complications After Gastrointestinal Surgery
Postoperative complications after gastrointestinal (GI) surgery remain a major source of morbidity, mortality, prolonged hospitalisation, and healthcare costs.
- Trial name
- DYNAMIC-GI (NCT07509710)
- Testing
- blood sampling
- Volunteers
- 1,500 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital