Clinical trials: Electric Countershock
Arrhythmia
Observation of ImageReady™ MR Conditional Defibrillation System in China
To observe the safety and effectiveness of ImageReady™ MR conditional defibrillation system in a Chinese population.
- Trial name
- NCT03451721
- Testing
- ImageReady™ MR Conditional Defibrillation System
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
Ventricular Arrythmia
A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing
This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with…
- Trial name
- PRAETORIAN-DFT (NCT03495297)
- Testing
- ommitence of defibrillation testing
- Where
- 32 sites in United States, Germany and 2 more
- Volunteers
- 965 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Atrial Fibrillation
Atrial Electromechanical Interval and Pulse Wave Velocity in the Prediction of Recurrence of Atrial Fibrillation
This study aims to evaluate the utility of the atrial electromechanical interval and pulse wave velocity in the prediction of recurrence of atrial fibrillation among patients who underwent successful direct current cardioversion…
- Trial name
- APPRAISE (NCT00818012)
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Creighton University
Atrial Fibrillation
Efficacy and Safety of Electrical Versus Pharmacological Cardioversion in Early Atrial Fibrillation
The optimal strategy to restore sinus rhythm in patients with atrial fibrillation (AF) of less than 48 hours' duration is still controversial.
- Trial name
- NCT00933634
- Testing
- electrical cardioversion, propafenone
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Valduce Hospital
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest
Double Sequential External Defibrillation (DSED) represents an alternative treatment of refractory ventricular fibrillation (rVF) in out-of-hospital cardiac arrest (OHCA).
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
- Trial name
- DUALDEFIB (NCT06672159)
- Testing
- Two defibrillators, One defibrillator
- Where
- Norway
- Volunteers
- 356 people
- Sponsor
- St. Olavs Hospital
Atrial Fibrillation
Antazoline in Comparison to Propafenone in Pharmacological Cardioversion of Atrial Fibrillation.
The purpose of this randomized, double blind, non-inferiority clinical trial was to compare the clinical efficacy and safety of antazoline with propafenone in the rapid conversion of paroxysmal non-valvular atrial fibrillation to…
- Trial name
- AnProAF (NCT05720572)
- Testing
- Antazoline, Propafenone
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Centre of Postgraduate Medical Education
Atrial Fibrillation
Efficacy and Safety Study of F373280
The purpose of this study is to assess the efficacy of F373280 on the maintenance of normal cardiac rhythm after direct electric cardioversion in patients with persistent atrial fibrillation and cardiac failure.
- Trial name
- NCT01831856
- Testing
- 1g of F373280
- Where
- 20 sites in Czechia, Hungary and 3 more
- Volunteers
- 135 people
- Sponsor
- Pierre Fabre Medicament
Atrial Fibrillation
Comparison of Efficacy and Safety of Different Doses of Nifekalant Instant Cardioversion of Persistent Atrial Fibrillation During Radiofrequency Ablation
Atrial fibrillation (AF) is one of the most common tachyarrhythmias with substantial morbidity, disability and mortality. It is estimated that the number of patients with AF is expected to reach 7 million by 2050.
- Trial name
- NCT04209959
- Testing
- nifekalant
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Atrial Fibrillation
Atrial Fibrillation Recurrence Following Cardioversion: the Role of Clinical Factors and Alpha Defensin Levels
Atrial fibrillation and inflammation are strongly correlated. The aim of this study is to evaluate whether inflammation markers (alpha Defensin) predict maintenance of sinus rhythm following cardioversion.
- Trial name
- NCT04155879
- Testing
- Colchicine Tablets, Cardioversion
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hillel Yaffe Medical Center
Pain
Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing
The use of lidocaine, as an anesthetic drug, during implantation of an implantable cardioverter-defibrillator(ICD)will not result in a clinically significant alteration of the defibrillation threshold during ICD placement.
- Trial name
- NCT03117166
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Drexel University College of Medicine
ICD and CRT-D Indicated Patients
The 4-SITE Field Following Study (4-SITE FF)
The purpose of this study is to evaluate and document appropriate clinical performance of the new 4-SITE Header / Lead interface in the TELIGEN 100 HE 4-SITE (VR and DR) implantable cardioverter defibrillator (ICD) PGs (Models…
- Trial name
- 4-SITE FF (NCT00920452)
- Where
- Germany
- Volunteers
- 430 people
- Sponsor
- Guidant Corporation
Atrial Fibrillation
Atrial Fibrillation Cycle Length Measured on Transesophageal Echocardiography
Background: The atrial fibrillation cycle length (AFCL) measured by electrophysiologic study is well known parameter for the maintenance of sinus rhythm after DC cardioversion (DCCV) or ablation therapy.
- Trial name
- NCT03496272
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Yangsan Hospital
Defibrillation Testing - ICD Therapy Optimisation
Trop-Shock DFT-testing Versus None
Implantation of a cardioverter defibrillator (ICD) is the treatment of choice for primary and secondary prevention of sudden cardiac death.
- Trial name
- Trop-Shock (NCT01230086)
- Testing
- ICD Implantation without DFT testing, Upper limit of vulnerability testing, T-wave shock with induction of ventricular fibrillation
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Cardiac Arrest, Fibrillation, Ventricular
Early Double Sequential Defibrillation in Out-of-hospital Cardiac Arrest
Some of the patients affected by Out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF)/ventricular tachycardia (VT) do not respond to initial defibrillation.
- Conditions
- Cardiac Arrest, Fibrillation, Ventricular, Sudden Cardiac Death, Sudden Cardiac Arrest
- Trial name
- DOUBLE-D (NCT06447805)
- Testing
- Double Sequential Defibrillation (DSD), Standard defibrillation
- Where
- 3 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation Mitral Valve Insufficiency
A Study on the Efficacy and Safety of TEER Combined With Electrical Cardioversion in Patients With Severe Mitral Regurgitation and Atrial Fibrillation
This study aims to evaluate the safety and efficacy of combined electrical cardioversion and TEER in patients with severe mitral regurgitation and atrial fibrillation after undergoing TEER.
- Trial name
- NCT07741383
- Testing
- TEER and Electrical Cardioversion
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atrial Fibrillation (AF), Atrial Flutter
Cardiologist-Administered Midazolam vs. Anaesthesiologist-Assisted Propofol Sedation For Transoesophageal Echocardiography-Guided Cardioversion of Atrial Fibrillation
Irregular heart rhythms, known as atrial fibrillation or atrial flutter, are common conditions that can increase the risk of stroke and heart failure.
- Trial name
- CARDIOZOLAM-1 (NCT07571447)
- Testing
- One-step cardiologist-only midazolam sedation, Two-step anaesthesiologist-assisted propofol sedation
- Where
- 2 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Gødstrup Hospital
Atrial Fibrillation, Cathter Ablation
A Randomized Controlled Study of Ablation Pursuing Atrial Fibrillation Termination as a Procedural Endpoint in Patients With Persistent Atrial Fibrillation
This is a prospective, randomized, multi-center trial that aims to investigate whether termination of atrial fibrillation can be used as an ablation endpoint for persistent atrial fibrillation (PersAF).
- Conditions
- Atrial Fibrillation, Cathter Ablation, Endpoint
- Trial name
- NCT05921734
- Testing
- AF-termination Group, Prespecified-ablation Group
- Where
- 2 sites in China
- Volunteers
- 480 people
- Sponsor
- Shanghai Chest Hospital
Ventricular Arrythmia, Ventricular Fibrillation
Assessment of a Chronically Implanted Parasternally Delivered EV-ICD Lead (ASCEND EV) Study
The ASCEND EV Study is a prospective, multi-center, single-arm, non-randomized study without concurrent or historical controls. The purpose of the study is to evaluate the Investigational Devices through at least 3-months of…
- Conditions
- Ventricular Arrythmia, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- ASCEND EV (NCT06592001)
- Testing
- Atala™ lead
- Where
- 3 sites in Croatia, New Zealand and 1 more
- Volunteers
- 19 people
- Sponsor
- AtaCor Medical, Inc.
Atrial Fibrillation
Non-vitamin K Oral Anticoagulants in Cardioversion
Non-vitamin K oral anticoagulants (NOAC) have been shown to be safe and effective alternatives to warfarin for stroke prevention in patients with nonvalvular AF (NVAF).
- Trial name
- FinCV3 (NCT02911545)
- Volunteers
- 1,000 people
- Sponsor
- Helsinki University Central Hospital
Atrial Fibrillation
The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow
The proposed research will investigate whether the irregular effects of atrial fibrillation on the body's circulation directly impacts the regulation of cerebral blood flow.
- Trial name
- NCT00745602
- Testing
- non-invasive testing
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center