Clinical trials: Electric Countershock
Atrial Fibrillation
Atrial Fibrillation Detection Using Garmin Wearable Technology
The purpose of this study is to evaluate the feasibility of detecting atrial fibrillation (AF) in patients with AF using a wearable wrist device/smart watch.
- Trial name
- GARMIN AF (NCT03566836)
- Testing
- Garmin Smart Watch, Garmin Chest Band
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Cardiac Arrest (CA)
Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest
The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with…
- Trial name
- STRAT-DEFI (NCT06781892)
- Testing
- Anterior-lateral pad positioning, Anterior-posterior pad positioning, Double-sequential defibrillation
- Where
- 6 sites in Denmark
- Volunteers
- 909 people
- Sponsor
- Lars Wiuff Andersen
Atrial Fibrillation
The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation
This study seeks to determine the efficacy of single coil defibrillation leads for cardioversion of persistent atrial fibrillation.
- Trial name
- NCT03164395
- Testing
- Internal Cardioversion, External Cardioversion
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Kentucky
Atrial Fibrillation
KONVERT-AF - Relevance of Point in Time for Conversion of Acute Atrial Fibrillation
To investigate if in acute symptomatic atrial fibrillation (AF) the early (>2 hrs but within 12 hrs of the beginning of the arrhythmia) electrical cardioversion leads to a longer recurrence-free interval than the delayed…
- Trial name
- NCT00369330
- Testing
- external electrical cardioversion
- Where
- Germany
- Sponsor
- Atrial Fibrillation Network
Arrhythmia, Quality of Life
Psychosomatic Effects of Implantable Cardioverter Defibrillator With Home Monitoring Function (QUANTUM)
Quality of life (QOL) and psychological well-being of patients with implantable cardioverter-defibrillators (ICDs) are significantly influenced by the experience of shock therapies.
- Trial name
- NCT00325221
- Testing
- HM on, HM Off
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 148 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation
EPLERAF-Study: Eplerenone in the Prevention of Atrial Fibrillation Recurrences After Cardioversion
The purpose of this study is to determine whether Eplerenone reduces atrial fibrillation (AF) recurrences within the first 8 weeks after electrical cardioversion of persistent AF.
- Trial name
- EPLERAF (NCT00647192)
- Testing
- Eplerenone
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 38 people
- Sponsor
- University Hospital, Saarland
Tachyarrhythmia
Lead Evaluation for Defibrillation and Reliability Post Approval Study
Medtronic is sponsoring the LEADR PAS to provide continuing evaluation and periodic reporting of safety and effectiveness of the OmniaSecure™ defibrillation lead following commercial release.
- Trial name
- LEADR PAS (NCT07005232)
- Testing
- defibrillation lead
- Where
- 97 sites in United States, Austria and 7 more
- Volunteers
- 2,000 people
- Sponsor
- Medtronic
Cardiac Arrest
Improving Defibrillation Pad Position
Manufacturer's diagrams showing defibrillation pad positioning (as used on public access defibrillators) are anatomically incorrect and are likely to lead to poor position of defibrillation pads, with reduced defibrillation…
- Trial name
- NCT03476720
- Testing
- Pad positioning according to a manufacturer's diagram
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Atrial Fibrillation (AF), Atrial Flutter
Electrophysiological Registry Duesseldorf
This registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Supraventricular Tachycardias, Ventricular Tachycardia (VT)
- Trial name
- NCT07196176
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Atrial Fibrillation, Atrial Flutter
Anteroposterior Versus Anterolateral Electrode Position for Electrical Cardioversion of Atrial Fibrillation
Atrial fibrillation is the most common heart rhythm disorder (arrhythmia) worldwide. Nearly 40 million people are affected by atrial fibrillation worldwide, and this number is expected to increase by over 50% by 2050.
- Trial name
- SHOCK-VECTOR (NCT05511389)
- Testing
- Anterolateral electrode position, Anteroposterior electrode position, Manual pressure
- Where
- 4 sites in Canada
- Volunteers
- 1,750 people
- Sponsor
- McMaster University
Atrial Fibrillation, Electric Countershock
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart.
- Conditions
- Atrial Fibrillation, Electric Countershock, Deep Sedation
- Trial name
- BIS-ECV-RCT (NCT07569016)
- Testing
- BIS-guided propofol sedation, Clinical-guided propofol sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Cardiac Arrest
RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest.
- Trial name
- NCT04660526
- Testing
- Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use.
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Duke University
Stroke, Transient Ischemic Attacks
Atrial Fibrillation as a Cause of Stroke and Intracranial Hemorrhage Study (The FibStroke Study)
The aim of this study is to evaluate the role of atrial fibrillation (AF) and its treatment in relation to thromboembolic events (stroke, and transient ischemic attacks) and intracranial hemorrhage.
- Conditions
- Stroke, Transient Ischemic Attacks, Intracranial Hemorrhage, Atrial Fibrillation
- Trial name
- FibStroke (NCT02146040)
- Where
- 4 sites in Finland
- Volunteers
- 5,885 people
- Sponsor
- University of Turku
Cardiac Death, Cardiac Arrest
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital.
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Trial name
- NCT04295291
- Volunteers
- 300 people
- Sponsor
- Ostfold University College
Tachycardia
Safety and Performance Study of the Reliance 4-Front Lead
The objective of this study is to gather data to establish the chronic safety, performance and effectiveness of the RELIANCE 4-FRONT™ Active Fixation Defibrillation Leads.
- Trial name
- NCT01772576
- Testing
- Reliance 4-Front lead implantation
- Where
- 15 sites in Austria, China and 9 more
- Volunteers
- 167 people
- Sponsor
- Boston Scientific Corporation
Paroxysmal Atrial Fibrillation
Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled clinical study designed to evaluate the efficacy and safety of FlecIH-103 (flecainide acetate inhalation solution) compared with placebo in patients…
- Trial name
- RESTORE-1 (NCT05039359)
- Testing
- FlecIH-103
- Where
- 40 sites in United States, Czechia and 4 more
- Volunteers
- 54 people
- Sponsor
- InCarda Therapeutics, Inc.
Atrial Fibrillation, Atrial Fibrillation, Persistent
Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm
The aim of this study is to evaluate benefits of electric cardioversion in the early and long-term postoperative period in patients after radiofrequency catheter isolation of pulmonary veins.
- Trial name
- NCT06654401
- Testing
- Transthoracic echocardiography, 24-hour ECG Monitor, Electroanatomic mapping
- Where
- Russia
- Volunteers
- 125 people
- Sponsor
- Saint Petersburg State University, Russia
DFT Testing
50/50% Tilt and Tuned Defibrillation Waveform
Study Description The purpose of this study is to compare the defibrillation efficacy between the 50/50% tilt biphasic waveform and the Tuned biphasic waveform utilizing High Voltage Lead Integrity Check (HVLIC) impedance.
- Trial name
- NCT01325922
- Testing
- DFT Testing with a 50/50% tilt
- Sponsor
- Abbott Medical Devices
Congestive Heart Failure
Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure
The purpose of this study is to determine whether combined mortality and hospitalization in heart failure patients receiving optimal pharmacologic therapy can be reduced by combining optimal pharmacologic therapy and 1)…
- Trial name
- NCT00180258
- Testing
- Cardiac Resynchronization Therapy with & without defibrillator
- Where
- United States
- Volunteers
- 2,200 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation (AF)
Optimal Shock Energy for Electrical Cardioversion of Atrial Fibrillation
Introduction For elective electrical cardioversion of atrial fibrillation, the recommended standard is the administration of a biphasic direct current shock.
- Trial name
- NCT07610980
- Testing
- Direct current biphasic electrical cardioversion, blood sampling
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Motol and Homolka University Hospital