Clinical trials: Electric Countershock
Paroxysmal Atrial Fibrillation
Antazoline in Rapid Cardioversion of Paroxysmal Atrial Fibrillation
The purpose of this randomized, double blind, placebo-controlled, superiority clinical trial was to assess clinical efficacy of antazoline in rapid conversion of atrial fibrillation during observation sinus rhythm.
- Trial name
- AnPAF (NCT01527279)
- Testing
- antazoline, 0.9% saline
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Chronic Heart Failure
Cardioversion of Atrial Fibrillation Accompanied by Chronic Heart Faliure
The purpose of this study is to explore the efficacy of low energy cardioversion on atrial fibrillation accompanied with chronic heart failure treated with HTEA or usual medicine.
- Trial name
- NCT02292030
- Testing
- HTEA
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Harbin Medical University
Atrial Fibrillation, Paroxysmal
Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation.
The purpose of this randomized, double blind, placebo-controlled, superiority clinical trial was to assess clinical efficacy of potassium canrenoate - canrenone in rapid conversion of atrial fibrillation to sinus rhythm.
- Trial name
- CANREN-AF (NCT03536806)
- Testing
- Saline 0.9%, Canrenone
- Volunteers
- 80 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Hypothermia, Accidental, Defibrillation
Defibrillation in Accidental Hypothermia
Hypothermia (core temperature ≤35°C) is a frequent and life-threatening complication after mountain accidents, near-drowning, and intoxications, and can provoke arrhythmia, reduced cardiac contractility, and cardiac arrest.
- Trial name
- NCT06131892
- Testing
- Defibrillation
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation
Study of the Effect of Cardioversion on Cardiac Volume in Patients With Persistent Atrial Fibrillation
The main objectives in this study were to examine the cardiac structural and functional changes in patients with persistent and permanent AF, with the aim of improving our understanding of the underlying pathophysiological…
- Trial name
- NCT00209911
- Testing
- cardioversion
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
New Onset Atrial Fibrillation
Anticoagulant and Antiarrhythmic Management Based on Continuous Rhythm Monitoring
This pilot study aims to assess the feasibility and safety of using an ILR to identify the incidence of recurrent AF after an episode of newly diagnosed AF.
- Trial name
- NCT04038944
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- St. Francis Hospital, New York
Atrial Fibrillation
Clinical Trial Comparing Devices Used for Cardioversion of Atrial Fibrillation
The goal of this single center, investigator initiated, open label prospective randomized controlled trial is to compare the efficacy of a single 200J RBW shock and a single 360J BTE shock.
- Trial name
- NCT05992623
- Testing
- Zoll external defibrillator, Lifepak external defibrillator
- Where
- United States
- Volunteers
- 546 people
- Sponsor
- Inova Health Care Services
Atrial Fibrillation, Arrhythmia
mHealth Rhythm Management in Terms of Cancelling Unnecessary Scheduled ECVs in Presumed Persistent AFpatients.
Despite a clear definition in the European Society of Cardiology (ESC) guidelines, the differentiation between paroxysmal (self-terminating) and persistent (nonself- terminating) atrial fibrillation (AF) remains challenging in…
- Conditions
- Atrial Fibrillation, Arrhythmia, Mobile Health, Electrical Cardioversion
- Trial name
- TeleConvert-AF (NCT06359132)
- Where
- 2 sites in Netherlands
- Volunteers
- 270 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation
BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure
Background: A Danish study raised the question of the usefulness of escalating energy protocols compared to fixed high-energy protocols. Maximal energies are usually the final choice of the physicians.
- Trial name
- NCT05316753
- Testing
- Cardioversion with a pulsed biphasic waveform, Cardioversion with a biphasic truncated exponential waveform
- Where
- Bulgaria
- Volunteers
- 94 people
- Sponsor
- University National Heart Hospital
Atrial Fibrillation (AF), Heart Failure - NYHA II - IV
Cardiovascular Performance and Exercise Response in Patients With Persistent or Permanent Atrial Fibrillation and Heart Failure Pre and Post Cardioversion or Pace and Ablate
Heart Failure (HF) and Atrial Fibrillation (AF) are two conditions that commonly occur together. Clinical guidelines consider a resting heart rate of 100-110 beats per minute (bpm) acceptable for patients with HF and AF while 72…
- Conditions
- Atrial Fibrillation (AF), Heart Failure - NYHA II - IV, Pacemaker, Cardioversion
- Trial name
- CPEX-CPA (NCT07205679)
- Volunteers
- 40 people
- Sponsor
- Habib Khan
Atrial Fibrillation, Atrial Flutter
Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.
- Trial name
- NCT04187196
- Testing
- Propofol, Methohexital
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Wake Forest University Health Sciences
Fibrillation, Atrial
Evaluation of Fondaparinux in Patients With a Heart Rhythm Disturbance Who Undergo Restoration of Normal Heart Rhythm
The purpose of this study is to test whether Fondaparinux is effective and safe to prevent thromboembolic events (like for example strokes) and bleeding events in patients who undergo a normalisation of their heart rhythm…
- Trial name
- NCT00911300
- Testing
- fondaparinux, unfractionated heparin, Vitamin-K-Antagonist
- Where
- 34 sites in France, Germany
- Volunteers
- 349 people
- Sponsor
- GlaxoSmithKline
Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation
A Study on the Impact of a New Canton-Wide First Responder System in Zug, Switzerland, on Survival After Adult Cardiac Arrest-Examining Early Life-Saving Organized Help, Fast Defibrillation, and Improved Outcomes for Out of Hospital Cardiac Arrest
REVIVE Zug: Improving Emergency Response for Out-of-Hospital Cardiac Arrest Out-of-hospital cardiac arrest (OHCA) represents one of the most time-critical medical emergencies, where rapid recognition and immediate intervention…
- Conditions
- Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation, Resuscitation, Emergency Medical Services
- Trial name
- REVIVE Zug (NCT07323667)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Felix Brinkmann
Atrial Fibrillation
Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)
Some people can develop an abnormal heart beat known as "Atrial fibrillation" or "AF" that puts them at risk of developing clots in the heart.
- Trial name
- EMANATE (NCT02100228)
- Testing
- Apixaban, Parenteral heparin and/or oral Vitamin K antagonist
- Where
- 165 sites in United States, Belgium and 10 more
- Volunteers
- 1,500 people
- Sponsor
- Pfizer
Atrial Fibrillation
Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation
The purpose of this study is to determine the long-term efficacy of radiofrequency catheter ablation in patients with chronic atrial fibrillation.
- Trial name
- NCT00272636
- Testing
- Radiofrequency catheter ablation, Amiodarone and cardioversion
- Where
- 2 sites in United States, Italy
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Atrial Fibrillation
Atrial Fibrillation Prior and Post Elective Cardioversion
Cardioversion from atrial fibrillation (AF) to sinus rhythm (SR) is performed primarily to improve patient symptoms. However, due to the intermittent nature of AF, patients may have converted to SR prior to elective cardioversion…
- Trial name
- NCT05926401
- Testing
- ECG monitoring prior and after cardioversion
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sorlandet Hospital HF
Ventricular Fibrillation
High Low Biphasic Energy Defibrillation (HiLoBED)
This inhospital study aims to compare the efficacy of high-versus low-energy biphasic shocks in order to determine the optimal level for defibrillation. Time is the essence when attending to a VF patient.
- Trial name
- NCT00429611
- Testing
- Cardiac defibrillation at high energy vs low energy levels
- Where
- 7 sites in Singapore
- Volunteers
- 600 people
- Sponsor
- Singapore General Hospital
Atrial Fibrillation
Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) Study
This is a sequential phase 1 and phase 2 study to evaluate the efficacy of intracardiac echocardiography to detect septal and left atrial pathology as compared to transesophageal echocardiography (Phase 1) and its value in a…
- Trial name
- ICE-CHIP (NCT00281073)
- Testing
- Intra-Cardiac Echocardiography guided Cardioversion, Intracardiac Echo, ICE
- Where
- 6 sites in United States, Netherlands
- Volunteers
- 95 people
- Sponsor
- EP MedSystems
Implantable Cardioverter-Defibrillators
Defibrillation Testing During Implantable Cardioverter Defibrillator (ICD) Replacement
This study will evaluate safety and clinical outcomes of a systematic defibrillation threshold testing in patient with indication for defibrillator replacement.
- Trial name
- T-DEF (NCT04206371)
- Testing
- Defibrillator threshold testing
- Where
- 7 sites in France
- Volunteers
- 143 people
- Sponsor
- CMC Ambroise Paré
Atrial Fibrillation
Comparison of High Versus Escalating Shocks in Cardioverting Atrial Fibrillation
Atrial fibrillation is the most common heart rhythm disorder. For patients suffering atrial fibrillation direct current cardioversion is performed to reduce patients symptoms and prevent disease progression.
- Trial name
- NCT02923414
- Testing
- Standard escalating shocks, High energy shock protocol
- Where
- Denmark
- Volunteers
- 276 people
- Sponsor
- University of Aarhus