Clinical trials: Electrical Cardioversion
Atrial Fibrillation
Assessment of Thrombotic Status in Patients With Atrial Fibrillation
Investigators will assess the impact of treatments for atrial fibrillation on participant's thrombotic status
- Trial name
- NCT02583971
- Volunteers
- 500 people
- Sponsor
- East and North Hertfordshire NHS Trust
Atrial Fibrillation
Efficacy and Safety of Electrical Versus Pharmacological Cardioversion in Early Atrial Fibrillation
The optimal strategy to restore sinus rhythm in patients with atrial fibrillation (AF) of less than 48 hours' duration is still controversial.
- Trial name
- NCT00933634
- Testing
- electrical cardioversion, propafenone
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Valduce Hospital
Atrial Fibrillation and Flutter, Heart Failure
Multimodal Cardiac Imaging Registry in Patients with Atrial Fibrillation
The goal of this observational registry is to collect a curated dataset of multimodal imaging data that will serve for development of artificial-intelligence based solutions for prediction of risk and outcomes in patients with…
- Conditions
- Atrial Fibrillation and Flutter, Heart Failure, Artificial Intelligence (AI), Echocardiography
- Trial name
- IMAGE-AF (NCT06584266)
- Testing
- Transoesophageal echocardiography, Catheter ablation
- Where
- 7 sites in Czechia, Poland
- Volunteers
- 3,000 people
- Sponsor
- University in Zielona Góra
Atrial Fibrillation, Atrial Flutter
Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter
Atrial fibrillation is a condition in which the heart's upper chambers, the atria, contract at an abnormally rapid rate. It is a common type of arrhythmia, and occurs in 1-2% of the general population.
- Trial name
- NCT01818583
- Testing
- Potassium chloride, Glucose 50 MG/ML
- Where
- Norway
- Volunteers
- 143 people
- Sponsor
- Diakonhjemmet Hospital
Atrial Fibrillation
Study on OMT-28 in Maintenance of Sinus Rhythm in Patients With Persistent Atrial Fibrillation (AF)
This is a randomized, double-blind, dose-finding, placebo-controlled, parallel group, multicenter, phase II study to evaluate the efficacy, safety, and popPK of three different doses of OMT-28 given once daily versus placebo in…
- Trial name
- PROMISE-AF (NCT03906799)
- Testing
- OMT-28
- Where
- 25 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 136 people
- Sponsor
- Omeicos Therapeutics GmbH
Atrial Fibrillation
EPLERAF-Study: Eplerenone in the Prevention of Atrial Fibrillation Recurrences After Cardioversion
The purpose of this study is to determine whether Eplerenone reduces atrial fibrillation (AF) recurrences within the first 8 weeks after electrical cardioversion of persistent AF.
- Trial name
- EPLERAF (NCT00647192)
- Testing
- Eplerenone
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 38 people
- Sponsor
- University Hospital, Saarland
Atrial Fibrillation
Amiodarone Compared to Dronedarone , Post Cardioversion Maintenance of Sinus Rhythm
Persistent Atrial Fibrillation (AF) is a common and distressing cardiac arrhythmia and accounts for 1% of the healthcare budget in the UK and it's prevalence is rising.
- Trial name
- ACDC (NCT01266681)
- Testing
- amiodarone, Dronedarone
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- East Sussex Healthcare NHS Trust
Out-of-hospital Cardiac Arrest (OHCA)
Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation
The purpose of this study is to evaluate, in patients presenting with out-of-hospital cardiac arrest (OHCA) by ventricular fibrillation, refractory to 3 external electric shocks, the efficacy of a direct intravenous injection of…
- Trial name
- POTACREH (NCT04316611)
- Testing
- Potassium chloride
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Pacing, Electric Countershock
Follow-up of Patients With Implantable Cardioverter Defibrillators by Home Monitoring (ANVITE)
Patients with implantable cardioverter defibrillators (ICDs) should undergo regular device follow-ups every 3 months, to verify proper ICD function.
- Conditions
- Cardiac Pacing, Electric Countershock, Ventricular Tachyarrhythmia
- Trial name
- ANVITE (NCT00858559)
- Testing
- Implantable cardioverter defibrillator with Home Monitoring function, Standard implantable cardioverter defibrillator
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation
Comparison of Efficacy and Safety of Different Doses of Nifekalant Instant Cardioversion of Persistent Atrial Fibrillation During Radiofrequency Ablation
Atrial fibrillation (AF) is one of the most common tachyarrhythmias with substantial morbidity, disability and mortality. It is estimated that the number of patients with AF is expected to reach 7 million by 2050.
- Trial name
- NCT04209959
- Testing
- nifekalant
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Atrial Arrhythmia, Heart Failure
Cologne Cardioversion Study
Implantation of internal defibrillators, capable of monitoring the heart and shocking life threatening arrhythmias back to normal rhythm, for patients with severe heart failure increases the probability of survival.
- Trial name
- NCT02241382
- Testing
- Internal Electrocardioversion, External Electrocardioversion
- Where
- 13 sites in Australia, Germany
- Volunteers
- 230 people
- Sponsor
- Universitätsklinikum Köln
Atrial Fibrillation, Atrial Flutter
Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.
- Trial name
- NCT04187196
- Testing
- Propofol, Methohexital
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Wake Forest University Health Sciences
Atrial Fibrillation (AF)
RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Dapagliflozin or Usual Care
The goal of this clinical trial is to learn if drug dapagliflozin, a sodium-glucose transport-2 inhibitor, works to treat atrial fibrillation in adults.
- Trial name
- RECUR-AF (NCT07187570)
- Testing
- Dapagliflozin 10 mg once daily
- Where
- 7 sites in Sweden
- Volunteers
- 1,600 people
- Sponsor
- Region Stockholm
Persistent Atrial Fibrillation
Acupuncture in Persistent Atrial Fibrillation
The aim of this trial is to evaluate the effect of acupuncture on prevention of atrial fibrillation (AF) recurrence after electrical cardioversion (EC) for persistent AF patients resistant to the antiarrhythmic drugs (AADs).
- Trial name
- NCT02110537
- Testing
- Active Acupuncture, flecainide
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kyunghee University Medical Center
Arrhythmia, Quality of Life
Psychosomatic Effects of Implantable Cardioverter Defibrillator With Home Monitoring Function (QUANTUM)
Quality of life (QOL) and psychological well-being of patients with implantable cardioverter-defibrillators (ICDs) are significantly influenced by the experience of shock therapies.
- Trial name
- NCT00325221
- Testing
- HM on, HM Off
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 148 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation
Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF)
The purpose of this study is to compare edoxaban to warfarin (with enoxaparin, if needed). It will see if edoxaban prevents stroke and other blood clotting problems as well and as safely as warfarin.
- Trial name
- ENSURE-AF (NCT02072434)
- Testing
- Edoxaban, Warfarin, Enoxaparin
- Where
- 228 sites in United States, Austria and 17 more
- Volunteers
- 2,199 people
- Sponsor
- Daiichi Sankyo
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients With Paroxysmal and Persistent Atrial Fibrillation and Flutter
The goal of this retrospective registry is to evaluate the efficacy and safety of Refralon®, concentrate for solution for intravenous injection, as chemical cardioversion in patients with paroxysmal and persistent atrial…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05773170
- Testing
- Refralon
- Where
- 33 sites in Russia
- Volunteers
- 1,147 people
- Sponsor
- R-Pharm
Ventricular Tachycardia, Ventricular Fibrillation
Leader - Evaluation of Endotak Reliance
The objective of this study is to demonstrate the efficacy of the ENDOTAK® RELIANCE™ defibrillation leads connected to a defibrillator or a cardiac resynchronization defibrillator from implant until 12 months.
- Trial name
- NCT00180349
- Testing
- Endotak Reliance
- Where
- 25 sites in France
- Volunteers
- 904 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation (AF)
Optimal Shock Energy for Electrical Cardioversion of Atrial Fibrillation
Introduction For elective electrical cardioversion of atrial fibrillation, the recommended standard is the administration of a biphasic direct current shock.
- Trial name
- NCT07610980
- Testing
- Direct current biphasic electrical cardioversion, blood sampling
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Motol and Homolka University Hospital
Atrial Fibrillation (AF), Atrial Flutter
Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)
The goal of this randomized clinical trial is to learn whether patients with symptomatic atrial fibrillation or atrial flutter (AF) who require heart imaging to rule out a blood clot before cardioversion would benefit from…
- Trial name
- LA CLOTTED (NCT07002450)
- Testing
- Cardiac computed tomography angiography, Standard of care management
- Where
- 3 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Ottawa Heart Institute Research Corporation