Clinical trials: Electrical Cardioversion
Atrial Fibrillation
Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation
The purpose of this study is to determine the long-term efficacy of radiofrequency catheter ablation in patients with chronic atrial fibrillation.
- Trial name
- NCT00272636
- Testing
- Radiofrequency catheter ablation, Amiodarone and cardioversion
- Where
- 2 sites in United States, Italy
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Out-of-hospital Cardiac Arrest (OHCA)
Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation
The purpose of this study is to evaluate, in patients presenting with out-of-hospital cardiac arrest (OHCA) by ventricular fibrillation, refractory to 3 external electric shocks, the efficacy of a direct intravenous injection of…
- Trial name
- POTACREH (NCT04316611)
- Testing
- Potassium chloride
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Safety of Cardioversion of Acute Atrial Fibrillation
The purpose of this study is to investigate the complications of cardioversion of acute (<48 hours duration) atrial fibrillation (AF).
- Trial name
- FinCV (NCT01380574)
- Where
- 3 sites in Finland
- Volunteers
- 7,700 people
- Sponsor
- Turku University Hospital
Atrial Fibrillation
A Study Evaluating the Efficacy and Safety of AP30663 for Cardioversion in Participants With Atrial Fibrillation (AF)
This study will evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of one or more doses of AP30663 for cardioversion in adult participants with AF.
- Trial name
- NCT04571385
- Testing
- AP30663
- Where
- 15 sites in Denmark, Hungary
- Volunteers
- 66 people
- Sponsor
- Acesion Pharma
Atrial Fibrillation
Intravenous Cardioversion of Atrial Fibrillation (AF) With AZD1305
This study is being carried out to see which dose of AZD1305 is safe and effective in cardioverting atrial fibrillation into normal heart rhythm.
- Trial name
- NCT00915356
- Testing
- AZD1305
- Where
- 31 sites in Czechia, Denmark and 6 more
- Volunteers
- 228 people
- Sponsor
- AstraZeneca
Atrial Fibrillation
Continuous Data Collection and Analysis for Stroke Prevention Using a Wearable Sensor
The purpose of this study is to determine whether a wristband that detects your pulse can detect your heart rate and rhythm similar to electrocardiograms (ECG).
- Trial name
- NCT03441022
- Testing
- Amiigo Watch Only, Amiigo Watch + BodyGuardian
- Sponsor
- Mayo Clinic
Atrial Fibrillation (AF)
Energy Dose and Cardioversion Outcomes in AF
This multicenter, randomized study will compare two electrical cardioversion energy strategies in adults with atrial fibrillation who are scheduled to undergo cardioversion during atrial fibrillation ablation or within 3 months…
- Trial name
- LE-HI-CV (NCT07884253)
- Testing
- Synchronized Electrical Cardioversion With Different Energy Strategies, Conventional Step-Up Energy Cardioversion
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Persistent Atrial Fibrillation, Cardiac Arrhythmia
Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)
The main aim of the research is to investigate whether patients undergoing pulmonary vein isolation with catheter ablation for persistent atrial fibrillation (AF) will have lower rates of AF recurrence than those treated by DC…
- Conditions
- Persistent Atrial Fibrillation, Cardiac Arrhythmia, Catheter Ablation
- Trial name
- ORBICA-AF (NCT06096246)
- Testing
- Pulmonary vein isolation, DC Cardioversion, Implantable loop recorder
- Where
- United Kingdom
- Volunteers
- 208 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation, Atrial Flutter
Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter
Atrial fibrillation is a condition in which the heart's upper chambers, the atria, contract at an abnormally rapid rate. It is a common type of arrhythmia, and occurs in 1-2% of the general population.
- Trial name
- NCT01818583
- Testing
- Potassium chloride, Glucose 50 MG/ML
- Where
- Norway
- Volunteers
- 143 people
- Sponsor
- Diakonhjemmet Hospital
Atrial Fibrillation
Canakinumab for the Prevention of Recurrences After Electrical Cardioversion: CONVERT-AF
The purpose of this study is to test the efficacy of a single injection of Canakinumab on AF recurrences within 6 months after electrical cardioversion in patients with persistent AF.
- Trial name
- CONVERT-AF (NCT01805960)
- Testing
- Canakinumab
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation, Arrythmia
Comparison of Efficacy and Safety of Two Biphasic Defibrillators in Cardioversion of Atrial Fibrillation
Background: Biphasic truncated exponential (BTE) waveforms are standard for cardiac defibrillation and synchronized cardioversion up to date.
- Conditions
- Atrial Fibrillation, Arrythmia, Electric Countershock
- Trial name
- NCT04032678
- Testing
- Schiller Defigard Touch 7 - DGT7, Schiller Medical, France, LIFEPAK 15, Physio-Control Inc., Redmond, WA, USA
- Where
- Bulgaria
- Volunteers
- 75 people
- Sponsor
- University National Heart Hospital
Atrial Fibrillation (AF), Atrial Flutter
Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)
The goal of this randomized clinical trial is to learn whether patients with symptomatic atrial fibrillation or atrial flutter (AF) who require heart imaging to rule out a blood clot before cardioversion would benefit from…
- Trial name
- LA CLOTTED (NCT07002450)
- Testing
- Cardiac computed tomography angiography, Standard of care management
- Where
- 3 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Atrial Fibrillation, Coffee
Does Eliminating Coffee Avoid Fibrillation?
Given both the increasing population impact of atrial fibrillation (AF) and the widespread consumption of coffee in society, determining an associated benefit or risk of coffee consumption on AF is of great clinical relevance.
- Trial name
- DECAF (NCT05121519)
- Testing
- Consume coffee, Avoid coffee
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Atrial Fibrillation, Atrial Flutter
Comparison of Oxygen Interventions and Defibrillator Efficiency
Background: Cardiac arrhythmias can be terminated by electrical current applied by an external defibrillator. This treatment, named cardioversion, has been used for decades in the treatment of atrial fibrillation.
- Trial name
- CODE (NCT02317029)
- Testing
- Cardioversion with a pulsed biphasic waveform, Normoxia during cardioversion, Cardioversion with a biphasic truncated exponential waveform
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- Randers Regional Hospital
Atrial Fibrillation, Atrial Flutter
Validation of a Novel Smartphone-based Method for Heart Rhythm Monitoring in the Home Environment
Atrial fibrillation is a heart rhythm disorder with increased risk of stroke, heart failure, dementia and death. The severity of symptoms in atrial fibrillation varies markedly, ranging from no symptoms to those with disabling…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Arrhythmia
- Trial name
- NCT04300270
- Testing
- Smartphone PPG recordings, Smartphone ECG
- Where
- Sweden
- Volunteers
- 480 people
- Sponsor
- Karolinska Institutet
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Atrial Fibrillation (AF), Heart Failure (HF)
Diagnostic Electrical Cardioversion for Explaining Patient's AF and HF Symptoms
Rationale: The co-existence of Atrial Fibrillation (AF) and Heart Failure (HF) is associated with increased morbidity, mortality, and hospital admissions, significantly contributing to healthcare burden.
- Conditions
- Atrial Fibrillation (AF), Heart Failure (HF), Electrical Cardioversion
- Trial name
- DEEP-AF-HF (NCT07000942)
- Testing
- Electrical cardioversion (ECV)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- M. Rienstra
Atrial Fibrillation
Study on OMT-28 in Maintenance of Sinus Rhythm in Patients With Persistent Atrial Fibrillation (AF)
This is a randomized, double-blind, dose-finding, placebo-controlled, parallel group, multicenter, phase II study to evaluate the efficacy, safety, and popPK of three different doses of OMT-28 given once daily versus placebo in…
- Trial name
- PROMISE-AF (NCT03906799)
- Testing
- OMT-28
- Where
- 25 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 136 people
- Sponsor
- Omeicos Therapeutics GmbH
Atrial Fibrillation
Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF)
The purpose of this study is to compare edoxaban to warfarin (with enoxaparin, if needed). It will see if edoxaban prevents stroke and other blood clotting problems as well and as safely as warfarin.
- Trial name
- ENSURE-AF (NCT02072434)
- Testing
- Edoxaban, Warfarin, Enoxaparin
- Where
- 228 sites in United States, Austria and 17 more
- Volunteers
- 2,199 people
- Sponsor
- Daiichi Sankyo
Cardiac Event, Sudden Cardiac Death
To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients
In this study, we are comparing the difference in outcomes between patients who were given shocks to the heart, during the upstroke of cardiopulmonary resuscitation (CPR) and before CPR is started.
- Conditions
- Cardiac Event, Sudden Cardiac Death, Death, Ventricular Fibrillation
- Trial name
- NCT01665755
- Testing
- Upstroke Compression Defibrillation, Precompression Defibrillation
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- Singapore General Hospital