Clinical trials: Electrical Cardioversion
Atrial Fibrillation, SGLT2 Inhibitor
Clinical Impact of SGLT2 Inhibitor After DC Cardioversion in Persistent AF With HFpEF
SGLT2 inhibitors improve outcomes in heart failure across the ejection fraction spectrum, but their effect on maintenance of sinus rhythm after rhythm-control therapy is largely unknown.
- Conditions
- Atrial Fibrillation, SGLT2 Inhibitor, DC Cardioversion
- Trial name
- NCT07776054
- Testing
- SGLT2 inhibitors (Dapagliflozin and Empagliflozin)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation
BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure
Background: A Danish study raised the question of the usefulness of escalating energy protocols compared to fixed high-energy protocols. Maximal energies are usually the final choice of the physicians.
- Trial name
- NCT05316753
- Testing
- Cardioversion with a pulsed biphasic waveform, Cardioversion with a biphasic truncated exponential waveform
- Where
- Bulgaria
- Volunteers
- 94 people
- Sponsor
- University National Heart Hospital
Atrial Fibrillation
Atrial Electromechanical Interval and Pulse Wave Velocity in the Prediction of Recurrence of Atrial Fibrillation
This study aims to evaluate the utility of the atrial electromechanical interval and pulse wave velocity in the prediction of recurrence of atrial fibrillation among patients who underwent successful direct current cardioversion…
- Trial name
- APPRAISE (NCT00818012)
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Creighton University
Current or Recent History of Atrial Fibrillation
Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
This study is being done to compare the effects of bucindolol hydrochloride (bucindolol) to metoprolol succinate (Toprol-XL) on the recurrence of symptomatic atrial fibrillation/atrial flutter in patients with heart failure who…
- Trial name
- GENETIC-AF (NCT01970501)
- Testing
- bucindolol hydrochloride, metoprolol succinate
- Where
- 97 sites in United States, Canada and 4 more
- Volunteers
- 267 people
- Sponsor
- ARCA Biopharma, Inc.
Atrial Fibrillation, Electrocardiography
CArdioversion of Short Duration Atrial Fibrillation
The study is aimed at testing the hypothesis whether atrial fibrillary rate (AFR), as a measure of atrial electrical remodeling assessed from surface ECG, is predictive of sinus rhythm maintenance after electrical cardioversion.
- Conditions
- Atrial Fibrillation, Electrocardiography, Electrical Remodeling
- Trial name
- CASAF (NCT02112318)
- Where
- 3 sites in Canada, Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Atrial Fibrillation (AF), Atrial Flutter
Cardiologist-Administered Midazolam vs. Anaesthesiologist-Assisted Propofol Sedation For Transoesophageal Echocardiography-Guided Cardioversion of Atrial Fibrillation
Irregular heart rhythms, known as atrial fibrillation or atrial flutter, are common conditions that can increase the risk of stroke and heart failure.
- Trial name
- CARDIOZOLAM-1 (NCT07571447)
- Testing
- One-step cardiologist-only midazolam sedation, Two-step anaesthesiologist-assisted propofol sedation
- Where
- 2 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Gødstrup Hospital
Cardioversion, Atrial Fibrillation
MAX - SHOCK Clinical Trial
Can Electrical Cardioversion (ECV) for AF be improved. It is the preferred method to restore sinus rhythm in patients with AF in whom a rhythm-control strategy is pursued.
- Trial name
- MAX-SHOCK (NCT06556667)
- Testing
- biphasic defibrillator with maximum energy of 200J (® Zoll), biphasic defibrillator with maximum energy of 360J (® Physio-Control)
- Where
- Canada
- Volunteers
- 376 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Atrial Fibrillation
A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of HSY244 in Participants With Atrial Fibrillation
This was a randomized, placebo-controlled, investigator- and participant-blinded study to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of HSY244 in participants with atrial fibrillation (AF), with and…
- Trial name
- NCT04582409
- Testing
- HSY244
- Where
- 4 sites in United States, Germany
- Volunteers
- 13 people
- Sponsor
- Novartis Pharmaceuticals
Atrial Fibrillation, Cardioversion
Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation
Patients with atrial fibrillation undergoing cardioversion will be randomized to undergo transesophageal echocardiography or they will receive warfarin for 3 weeks with an international normalized ratio (INR) value between…
- Conditions
- Atrial Fibrillation, Cardioversion, Cerebrovascular Stroke
- Trial name
- AFTER-CV (NCT01924065)
- Testing
- Cardioversion, Oral Anticoagulant
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Suleyman Demirel University
Atrial Fibrillation
Atrial Fibrillation Detection Using Garmin Wearable Technology
The purpose of this study is to evaluate the feasibility of detecting atrial fibrillation (AF) in patients with AF using a wearable wrist device/smart watch.
- Trial name
- GARMIN AF (NCT03566836)
- Testing
- Garmin Smart Watch, Garmin Chest Band
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Atrial Fibrillation
Efficacy of Propafenone Versus Dronedarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
the purpose of this study is to compare the ability of propafenone and dronedarone to maintain sinus rhythm after DC cardioversion
- Trial name
- NCT01991119
- Testing
- Propafenone, Dronedarone
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Samsung Medical Center
Cardiopulmonary Resuscitation (CPR), Electrical Shock
Effect of Electrically Insulated Gloves on ROSC Time, End-tidal CO₂ Response, Survival and Morbidity in Uninterrupted CPR
Cardiopulmonary arrest is the sudden cessation of spontaneous breathing and circulation due to various causes. Cardiopulmonary resuscitation (CPR) is the set of decisions and procedures encompassing all efforts aimed at restoring…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Electrical Shock, Defibrillation
- Trial name
- IG-CPR (NCT07299188)
- Testing
- HANDS ON BUT OFF DEFIBRILLATION
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Katip Celebi University
Atrial Fibrillation (AF), Heart Failure (HF)
Diagnostic Electrical Cardioversion for Explaining Patient's AF and HF Symptoms
Rationale: The co-existence of Atrial Fibrillation (AF) and Heart Failure (HF) is associated with increased morbidity, mortality, and hospital admissions, significantly contributing to healthcare burden.
- Conditions
- Atrial Fibrillation (AF), Heart Failure (HF), Electrical Cardioversion
- Trial name
- DEEP-AF-HF (NCT07000942)
- Testing
- Electrical cardioversion (ECV)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- M. Rienstra
Cardioversion
Myocardial Injury Following Elective Direct Current Cardioversion for Atrial Arrhythmias
Researchers are trying to determine if heart injury occurs in subjects who undergo direct current cardioversion.
- Trial name
- NCT04151966
- Testing
- Blood sample collection
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation
The Ottawa AF Cardioversion Protocol
Atrial fibrillation is an abnormal heart rhythm in which the top chambers of the heart (the atrial chambers) beat very fast. Electrical cardioversion is a technique to convert heart rhythm from AF to normal rhythm.
- Trial name
- NCT02192957
- Testing
- Lifepak 20E Defibrillator, Licence No: 61944
- Where
- Canada
- Volunteers
- 389 people
- Sponsor
- David Birnie
Atrial Fibrillation, Arrhythmia
mHealth Rhythm Management in Terms of Cancelling Unnecessary Scheduled ECVs in Presumed Persistent AFpatients.
Despite a clear definition in the European Society of Cardiology (ESC) guidelines, the differentiation between paroxysmal (self-terminating) and persistent (nonself- terminating) atrial fibrillation (AF) remains challenging in…
- Conditions
- Atrial Fibrillation, Arrhythmia, Mobile Health, Electrical Cardioversion
- Trial name
- TeleConvert-AF (NCT06359132)
- Where
- 2 sites in Netherlands
- Volunteers
- 270 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation
Atrial Fibrillation Cycle Length Measured on Transesophageal Echocardiography
Background: The atrial fibrillation cycle length (AFCL) measured by electrophysiologic study is well known parameter for the maintenance of sinus rhythm after DC cardioversion (DCCV) or ablation therapy.
- Trial name
- NCT03496272
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Yangsan Hospital
Persistent Atrial Fibrillation, Cardiac Arrhythmia
Investigation of Therapeutic Ablation Versus Cardioversion for AF
The main aim of the research is to investigate whether patients undergoing pulmonary vein isolation with cryoablation for atrial fibrillation (AF) will have lower rates of AF recurrence than those treated by DC cardioversion…
- Trial name
- ORBITA-AF (NCT03907982)
- Testing
- DC Cardioversion, Pulmonary vein isolation, Implantable loop recorder
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Persistent Atrial Fibrillation
Electrical Cardioversion, Ablation or Pace and Ablate for Persistent Atrial Fibrillation
Comparison of (i) catheter ablation, (ii) electrical cardioversion and (iii) pacemaker implantation with AV node ablation for patients over 65 years of age with persistent Atrial Fibrillation.
- Trial name
- CAPAPAF-65 (NCT02528604)
- Testing
- Catheter ablation, Pacemaker and AV node ablation, DC Cardioversion
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- East Sussex Healthcare NHS Trust
Atrial Flutter
Antero-posterior Versus Antero-lateral Electrode Position for Electrical Cardioversion of Typical Atrial Flutter
The aim of this study is to identify the one electrode position out of two most commonly used for external electrical cardioversion of typical atrial flutter, which needs less delivered energy and less needed number of shocks for…
- Trial name
- APOVERSAL (NCT00860314)
- Testing
- external electrical cardioversion (with antero-posterior electrode position), external electrical cardioversion (with antero-lateral electrode position)
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf