Clinical trials: Electrical Impedance Tomography (EIT)
Pulmonary Atelectasis
Atelectasis Formation: Role of Positive Pressure Breathing, Hyperoxia, and Hypobaria
The primary aim of this project is to get further knowledge of the physiology of flight atelectasis and its prevention. We seek to: 1) assess whether low levels of positive pressure breathing can prevent atelectasis formation in…
- Trial name
- NCT03311347
- Testing
- +Gz accelerations and positive pressure breathing
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Acute Respiratory Failure (ARF)
Lung Recruitment Assessed by 2D/3D-EIT and R/I Ratio in Acute Respiratory Failure Patients With Mechanical Ventilation
The purpose of this observational study is to assess the differences and consistency in evaluating lung recruitment potential between the recruitment-to-inflation ratio (R/I ratio) and three-dimensional electrical impedance…
- Trial name
- NCT07379242
- Testing
- The lung recruitment potential assessed and PEEP titration by ventilator and 2D/3D EIT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Atelectasis
Comparing the Effectiveness of Lung Expansion Therapy in Adult Human Subjects
The purpose of this study is to better understand how air is spread throughout study participants' lungs after abdominal surgery by comparing two lung inflation treatments: 1. Incentive Spirometry (I.S.) lung expansion therapy 2.
- Trial name
- NCT02892773
- Testing
- Incentive Spirometry, EzPAP® Positive Airway Pressure
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Virginia
Premature Infant, Chronic Respiratory Disease
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in…
- Conditions
- Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy
- Trial name
- NCT03797183
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Respiratory Distress Syndrome RDS, Preterm Birth
Early Prediction of Lung Injury in Preterm Infants Score
The main hypothesis is that even preterm infants considered "stable" receiving non-invasive ventilation may be at risk of developing BPD due to an inhomogeneous distribution of ventilation.
- Trial name
- EPLIPS (NCT07265583)
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Acute Respiratory Failure Requiring Intubation
A Study on the Assessment of Difficult Weaning in Patients With Acute Respiratory Failure Undergoing Mechanical Ventilation Based on Machine Learning EIT-pendelluft: A Multicenter Retrospective Study.
Invasive mechanical ventilation (IMV) is a common method used in the ICU to assist breathing and promote gas exchange. When a patient's condition improves, the weaning process (WP) should be initiated.
- Trial name
- NCT06756204
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ruijin Hospital
Postoperative Atelectasis
EIT-Guided Visual Feedback During Incentive Spirometry for Postoperative Atelectasis
This single-center randomized controlled trial will evaluate whether real-time visual feedback from electrical impedance tomography (EIT) improves the immediate distribution of lung ventilation during incentive spirometry in…
- Trial name
- NCT07681232
- Testing
- EIT-Guided Incentive Spirometry, Standardized Incentive Spirometry Guidance
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Pediatric Acute Respiratory Distress Syndrome
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced.
- Trial name
- NCT06684119
- Testing
- Electrical Impedance Tomography positive end-expiratory pressure titration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
ARDS, Prone Position
Determine the Effect of Prone Positioning in Adults With ARDS by Electrical Impedance Tomography
determine the effect of prone positioning on ventilation and perfusion distribution in adults with acute respiratory distress syndrome by electrical impedance tomography
- Conditions
- ARDS, Prone Position, Electrical Impedance Tomography
- Trial name
- NCT04725227
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Respiratory Distress Syndrome (ARDS)
Application of Electrical Impedance Tomography in Evaluating Pulmonary Function Improvement After High Lateral Recumbent Position Therapy in ARDS Patients
This randomized controlled trial investigates the effects of prone positioning versus lateral positioning at different angles (30°, 90°, 120°) on pulmonary function improvement in patients with acute respiratory distress syndrome…
- Trial name
- NCT07375849
- Testing
- Place the patient in the 90-degree high lateral position., Place the patient in the 30-degree low lateral position., Place the patient in the 120-degree high lateral position.
- Volunteers
- 140 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Critical Care, Weaning From Mechanical Ventilation
Lung Aeration During WEANing From Mechanical Ventilation Determined by Electrical Impedance Tomography and Lung Ultrasound
Evaluation of lung aeration during weaning from mechanical ventilation determined by electrical impedance tomography and lung ultrasound
- Conditions
- Critical Care, Weaning From Mechanical Ventilation, Electrical Impedance Tomography, End Expiratory Lung Volume
- Trial name
- IWEAN (NCT02361021)
- Testing
- - Weaning from mechanical ventilation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Lung Injury
Regional Lung Opening and Closing Pressures in Patients With Acute Lung Injury
The purpose of this study is the measurement of regional opening and closing pressures of lung tissue by electrical impedance tomography in lung healthy and patients with acute lung injury.
- Trial name
- NCT01107847
- Testing
- low flow pressure volume manoeuvre
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Schleswig-Holstein
ARDS
Electrical Impedance Tomography-Derived Dorsal Recruitment-to-Inflation Ratio Identifies PEEP Responsiveness and Risk Phenotypes in ARDS
In the treatment of critically ill patients, mechanical ventilation is a key link, and appropriate mechanical ventilation strategies can open the alveoli and improve oxygenation, while inappropriate mechanical ventilation can…
- Trial name
- NCT06823804
- Testing
- Electrical Impedance tomography Monitoring
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ruijin Hospital
Arteriovenous Graft Thrombosis, End Stage Renal Disease on Dialysis
Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis
Patients with end-stage renal disease (ESRD) often require arteriovenous grafts (AVG) for hemodialysis. AVG thrombosis is a common complication, usually managed by percutaneous transluminal angioplasty (PTA) to restore blood…
- Trial name
- NCT07613632
- Testing
- Electrical Impedance Tomography (EIT) Monitoring
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Acute Respiratory Distress Syndrome (ARDS), Ventilator-induced Lung Injury
Electrical Impedance Tomography-Based Prognostic Model for ARDS
This multicenter, prospective, observational study aims to develop and validate an EIT-based prognostic model for ARDS. By focusing on the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung…
- Trial name
- NCT06967207
- Testing
- Not applicable- observational study
- Where
- 4 sites in China
- Volunteers
- 625 people
- Sponsor
- XiaoJing Zou,MD
Abdominal Sepsis, Acute Respiratory Failure
Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy
The goal of this clinical trial is to evaluate regional ventilation distribution in patients admitted to the intensive care unit after emergent laparotomy due to abdominal sepsis.
- Conditions
- Abdominal Sepsis, Acute Respiratory Failure, Ventilation Therapy; Complications, Emergencies
- Trial name
- CHESTOMY (NCT05726500)
- Testing
- Arterial blood gas analysis, Venous blood gas analysis, Esophageal pressure monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Università degli Studi di Ferrara
Ventilation, Breathing
Pilot Evaluation Comparing Regional Distribution of Ventilation During Lung Expansion Therapy
The primary purpose of this study is to determine if there is a significant difference in regional distribution of ventilation when comparing eupneic tidal ventilation with Incentive Spirometry (I.S.) and EzPAP® lung expansion…
- Conditions
- Ventilation, Breathing, Atelectasis
- Trial name
- NCT03083379
- Testing
- Volumetric Incentive Spirometry, EzPAP® POSITIVE AIRWAY PRESSURE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Surfactant Deficiency Syndrome Neonatal
deMISTify: The Impact of Ventilator Pressure Levels During Minimally Invasive Surfactant Therapy on Lung Aeration in Preterm Infants
Infants born preterm (before 36 weeks' gestation age) have immature lungs and struggle to breathe on their own. They are supported via respiratory machines like ventilators, as well as pharmaceutical aids like surfactant…
- Trial name
- deMISTify (NCT07522346)
- Testing
- Lung Recruitment Manoeuvre prior to Minimally Invasive Surfactant Therapy, Control (Minimally Invasive Surfactant Therapy)
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- Murdoch Childrens Research Institute
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS
Right ventricular failure may be associated with mortality in patients with acute respiratory distress syndrome (ARDS). Mechanical ventilation may promote right ventricular failure by inducing alveolar overdistention and…
- Trial name
- RIGHTENARDS (NCT05583461)
- Testing
- Positive end-expiratory pressure titration
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- University of Padova
Comparison of Availability for Prediction of Volume Responsiveness, Comparison of Limits of Agreement for Invasive and Non-invasive Measurement of Stroke Volume Variation
Non-invasive Measurement of Central Hemodynamics by Electrical Impedance Tomography
The purpose of this study is to evaluate the ability to measure central hemodynamics and heart-lung interactions non-invasively by electrical impedance tomography and compare it to clinically established hemodynamic monitoring.
- Trial name
- NCT01412970
- Testing
- volume loading
- Where
- Germany
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf