Clinical trials: Electrical Impedance Tomography (EIT)
Acute Respiratory Failure
Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure
Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation.
- Trial name
- PELUCHE1 (NCT05347563)
- Testing
- Electrical impedance tomography
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
ALS
Feasibility of an Electrical Impedance Tomography Device for Pulmonary Function Testing in ALS Patients
This is an unblinded pilot study to investigate the technical feasibility of using an electrical impedance tomography device for noninvasive pulmonary function monitoring in ALS patients.
- Trial name
- NCT05287958
- Testing
- EIT
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Respiratory Failure, Acute Respiratory Distress Syndrome
Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography
Respiratory disorders are the leading cause of respiratory failure in children. Thousands of children are admitted to a pediatric intensive care unit each year and placed on mechanical ventilators.
- Conditions
- Respiratory Failure, Acute Respiratory Distress Syndrome, Acute Lung Injury
- Trial name
- EIT (NCT02247700)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston Children's Hospital
Bariatric Surgery Candidate, Atelectasis, Postoperative Pulmonary
Ventilation Distribution After Bariatric Surgery
Obese patients have an increased risk of developing post-operative respiratory complications due to their comorbidities. They have a restrictive ventilatory defect with reduction of lung volumes and expiratory flow limitation…
- Trial name
- NCT03975348
- Testing
- High flow nasal cannula, Continuous positive airway pressure, Facemask
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Trieste
COPD
Heterogeneity of Lung Ventilation Determined by EIT During PFT in Patients With PRISM
To evaluate the demographic characteristics of PRISm population in patients with pulmonary function tests recommended by outpatient physicians.
- Trial name
- NCT06199258
- Testing
- pulmonary function test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT)
Cyclic On-off Switching of Pulmonary Blood Flow in Moderate to Severe ARDS
Although the theoretical model of "cyclic on-off switching of pulmonary blood flow" provides a crucial perspective for understanding VILI, its clinical validation and real-time intervention face significant obstacles.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT), Pulmonary Perfusion
- Trial name
- NCT07327268
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
Laparoscopy
Ultrasound Detection of Position of Diaphragm During Laparoscopic Surgery
Position of diaphragm in the region of electrical impedance tomography measurement is to be determined by ultrasound in approx. 20 patients undergoing laparoscopic surgery.
- Trial name
- UDLaS (NCT03038061)
- Testing
- Patients undergoing Laparoscopic Surgery
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Czech Technical University in Prague
Acute Respiratory Distress Syndrome, ARDS
Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Doctors follow a standard ventilator management strategy when making adjustments to the breathing machine to optimize the amount of oxygen into the lungs.
- Trial name
- NCT03793842
- Testing
- Usual care, PEEP titration by EIT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Pregnancy Complications, Atelectasis
Effect of Epidural Analgesia on Regional Lung Ventilation in Parturient Women as Assessed by Thoracic Impedance
The goal of this observational study is to learn more about the effect of obstetric epidural anesthesia on regional lung ventilation in healthy parturient women.
- Trial name
- NCT06195774
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Acute Respiratory Failure (ARF), Hypertension
EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure
This prospective, single-center interventional study aims to evaluate the effect of two commonly used intravenous antihypertensive agents - nicardipine and nitroglycerin - on lung ventilation-perfusion (V/Q) distribution in…
- Conditions
- Acute Respiratory Failure (ARF), Hypertension, Pulmonary Perfusion Imbalance, Aortic Dissection (Subset)
- Trial name
- NCT07603037
- Testing
- Nitroglycerin, Nicardipine
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Pulmonary Atelectasis
Optimizing Intraoperative Mechanical Ventilation Using EIT-titrated PEEP
The purpose of this randomized single center study is to determine the individual PEEP value that produces the best possible compromise of lung collapse and lung hyperdistention.
- Trial name
- NCT02314845
- Testing
- Optimal PEEP, Low PEEP
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Epilepsy, Tumor
High-density EEG in Neurological Disorders
The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.
- Conditions
- Epilepsy, Tumor, Healthy
- Trial name
- NCT04266041
- Testing
- High-density electroencephalogram (HD-EEG)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acute Respiratory Distress Syndrome
Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study)
RAGE, the receptor for advanced glycation end products, is a novel marker of alveolar epithelial type I cell injury, and soluble RAGE (sRAGE) is elevated in the plasma and in the pulmonary edema fluid from patients with ALI/ARDS.
- Trial name
- DAMAGE (NCT01600651)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy Volunteers Only
A Study of Body Fat Distribution and Airway Mechanics in Healthy Adults
This study investigates how body fat distribution affects airway closure and lung mechanics in healthy adults. Using Electrical Impedance Tomography (EIT), esophageal manometry, and computed tomography (CT), we aim to…
- Trial name
- NCT07019831
- Testing
- Body positioning
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maurizio F. Cereda, MD
Recruitment, Respiratory Failure
Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study
This single-center observational study aims to assess the effects of continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy on lung recruitment using electrical impedance…
- Trial name
- PEP-RECRUIT (NCT06689020)
- Testing
- Continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Genova
Electric Impedance Tomography, Bronchoscopy
Bronchoscopy and Electric Impedance Tomography (EIT) Pilot Study
Electrical Impedance Tomography (EIT)is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice…
- Conditions
- Electric Impedance Tomography, Bronchoscopy, Change in Lung Impedance Due to Ventilation, Recruitment
- Trial name
- Broncho-EIT (NCT01294813)
- Testing
- Electrical Impedance Tomography (EIT)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- RWTH Aachen University
Acute Respiratory Failure
Lung Aeration After Flexible Bronchoscopy in Intubated Critically Ill Patients
In patients suffering from acute respiratory failure, ineffective cough and the consequent retention of secretions are common clinical problems, which often lead to the need for tracheostomy for the sole purpose of aspiration of…
- Trial name
- NCT05200494
- Testing
- Recruiting Maneuver
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University Magna Graecia
ARDS, Human
EIT in Patient Ventilator Asynchrony
Patient-ventilator asynchrony is an important clinical issue in mechanically ventilated patients. For patients with moderate to severe acute respiratory distress syndrome (ARDS), various types of patient ventilator asynchrony may…
- Trial name
- NCT04442815
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Cheng-Kung University Hospital
Pulmonary Ventilation
Distribution of Pulmonary Ventilation With the Modified Pachon Incentive vs. Branded Respiratory Incentive
Incentive spirometry is a method to stimulate deep breathing and maximum sustained inflations, which provides participants with visual feedback on the inspiratory volume achieved, favoring lung inflation.
- Trial name
- NCT05532748
- Testing
- Respiratory exercise protocol with the modified Pachon's incentive, Respiratory exercise protocol with Branded respiratory incentive, "Triflo II®"
- Where
- Colombia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Mechanical Power, Postoperative Pulmonary Complications (PPCs)
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing…
- Conditions
- Mechanical Power, Postoperative Pulmonary Complications (PPCs), Oxygenation
- Trial name
- TITRANT (NCT07170514)
- Testing
- EIT-guided PEEP titration, Cdyn-guided PEEP titration
- Where
- 3 sites in Hungary
- Volunteers
- 200 people
- Sponsor
- Pest County Flór Ferenc Hospital