Clinical trials: Electrical Impedance Tomography (EIT)
Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography: A Prospective Pilot Study
The goal of this observational pilot study is to learn if sodium bicarbonate can be used safely and effectively as a contrast agent to map lung blood flow using electrical impedance tomography (EIT) in adults on mechanical…
- Conditions
- Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Pneumonia, Critical Illness
- Trial name
- NCT07542366
- Where
- China
- Volunteers
- 41 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Acute Respiratory Distress Syndrome, Prone Position
Improvement of ARDS Ventilation-perfusion Matching by Prone Positioning Assessed by EIT
Acute Respiratory Distress Syndrome (ARDS) is a highly lethal disease with limited treatment options. In recent years, prone position ventilation has been shown to improve the mortality rate and lung injury of ARDS patients by…
- Conditions
- Acute Respiratory Distress Syndrome, Prone Position, Electrical Impedance Tomography
- Trial name
- NCT05765760
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Beijing Chao Yang Hospital
Intensive Care
Bedside Measurement of Ventilation With or Without a One-way Valve During Lung Lavage
Surveillance of the lungs for bacteria is routinely undertaken in artificially ventilated patients as these individuals are at high risk of developing pneumonia.
- Trial name
- NCT01143961
- Testing
- CSC100 - Verso airway access adapter CareFusion
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cardiff and Vale University Health Board
Occult Bleeding, Hemorrhage
A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage
Early detection of ongoing hemorrhage (OH) before onset of hemorrhagic shock is a universally acknowledged great unmet need, and particularly important after traumatic injury.
- Conditions
- Occult Bleeding, Hemorrhage, Hemorrhagic Shock
- Trial name
- NCT04814810
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Respiratory Failure, Heart Rate Variability (HRV)
Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy
High-flow nasal cannula is a type of non-invasive respiratory support that helps patients breathe more comfortably. Because the flow is high, it can deliver more oxygen to the lungs and make breathing easier by reducing the…
- Conditions
- Respiratory Failure, Heart Rate Variability (HRV), High Flow Nasal Cannula
- Trial name
- VARIATION (NCT07518862)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
EIT Electrode Belt Stiffness, Tidal Volume Changes
Effect of Electrode Belt Used for Lung Monitoring With EIT on Tidal Volume
Tidal volumes of ten spontaneously breathing healthy volunteers were measured using spirometer in two situations: wearing EIT electrode belt and without electrode belt.
- Trial name
- NCT06419790
- Testing
- EIT electrode belt, spirometry
- Where
- Czechia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Lung Function Decreased
Pulmonary Ventilation Heterogeneity Determined by EIT During PFT in Subjects With Normal One-second Rates
To evaluate the demographic characteristics of normal one-second rates population in patients with pulmonary function tests recommended by outpatient physicians.
- Trial name
- NCT06407986
- Testing
- pulmonary function test
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sir Run Run Shaw Hospital
Acute Respiratory Failure With Hypoxia
High-flow Oxygen Therapy vs Non-invasive Ventilation: Comparison of Alveolar Recruitment in Acute Respiratory Failure
This physiological study showed an increase in regional ventilation with NIV but no difference in alveolar recruitment as compared to HFNC in patients with hypoxemic ARF.
- Trial name
- IRAvista (NCT04664322)
- Testing
- non invasive ventilation and high flow nasal canulae oxygen therapy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Rouen
Acute Respiratory Distress Syndrome
Early PP Monitored by EIT in Patients With ARDS
Acute Respiratory Distress Syndrome (ARDS) is a syndrome characterized by respiratory distress and refractory hypoxemia caused by pulmonary and extra-pulmonary factors.
- Trial name
- NCT05822869
- Testing
- EIT-guided mechanical ventilation strategy, Lung protective ventilation group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Chao Yang Hospital
COPD, Non Invasive Ventilation (NIV)
The Feasibility of Electrical Impedance Tomography to Guide Non-invasive Respiratory Interventions in Chronic Respiratory Disease
This study aims to use Electrical Impedance Tomography (EIT) to optimise breathing machines for people with problems with their breathing. This might improve their ability to use their breathing machine.
- Conditions
- COPD, Non Invasive Ventilation (NIV), Obesity, Neuromuscular Disability
- Trial name
- EIT-Guide (NCT07810283)
- Testing
- electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Hypoxemia of Newborn
Lung Function Monitoring During Hypoxemia Episodes
Premature infants commonly have desaturation episodes due to different reasons such as cessation of breathing or loss of lung volume.
- Trial name
- NCT06535074
- Testing
- Detecting changes in lung volume with hypoxemia episodes
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Rutgers, The State University of New Jersey
Acute Respiratory Distress Syndrome
EIT Assessment of Overdistension in ARDS Patients in Prone Position
Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung.
- Trial name
- DISTIE-DV (NCT06536543)
- Testing
- Acute Respiratory Distress Syndrom (ARDS) treated with Prone Position (PP) equipped with Electrical Impedance Tomography (EIT)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Severe ARDS
Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO
For ECMO supported patients with severe ARDS (acute respiratory distress syndrome), usual care include use of "ultraprotective" mechanical ventilation with tidal volume and pressure reductions that might ultimately enhance lung…
- Trial name
- EIT-ECMO (NCT05717218)
- Testing
- Ultra-protective mechanical ventilation monitored by electrical impedance tomography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Contusion
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow…
- Trial name
- NCT06386120
- Testing
- PEEP setting strategy
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Pulmonary Embolism Acute
Pulsatile Electrical Impedance Tomography for Diagnosis and Monitoring of Acute Pulmonary Embolism
This multicenter observational diagnostic study aims to evaluate pulsatile electrical impedance tomography (EIT) for the diagnosis and monitoring of acute pulmonary embolism.
- Trial name
- EIT-PE (NCT07724197)
- Testing
- Pulsatile Electrical Impedance Tomography
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Pneumoperitoneum, Trendelenburg Position
End-expiratory Pressure During Laparoscopic Surgery in the Trendelenburg Position by Electrical Impedance Tomography
Pneumoperitoneum (PNP) and the position of the patient required for laparoscopic surgery lead to pathophysiological changes that complicate anesthesia.
- Conditions
- Pneumoperitoneum, Trendelenburg Position, Laparoscopic Surgery
- Trial name
- CP-EIT (NCT06481124)
- Testing
- electrical impedance tomography
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Ventilatory Failure, Hypoxemic Respiratory Failure
PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study
The goal of this observational study is to assess the potential non-invasive tools (e.g. regional ventilation, respiratory muscle response, lung mechanic's parameters) to identify the risk of failure when using high flow nasal…
- Conditions
- Ventilatory Failure, Hypoxemic Respiratory Failure, Weaning Failure, Respiratory
- Trial name
- PREVISION (NCT06716463)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Unity Health Toronto
Electrical Impedance Tomography
Evaluation of Postoperative Ventilation Distribution With Electrical Impedance Tomography
Postoperative patients require respiratory management . It is known that the intrapulmonary ventilation distribution becomes uneven due to dorsal atelectasis and ventral hyperinflation during mechanical ventilation management…
- Trial name
- NCT05389735
- Where
- Japan
- Volunteers
- 130 people
- Sponsor
- Osaka University
PreTerm Neonate, Positive End Expiratory Pressure (PEEP)
PEEP FOR LUNG RECRUITMENT IN PRETERM INFANTS-EIT STUDY
Babies born early (under 32 weeks) are at risk of developing lung problems after birth. A major reason for this is that the lungs are not fully developed.
- Conditions
- PreTerm Neonate, Positive End Expiratory Pressure (PEEP), Lung Recruitment, Electrical Impedance Tomography (EIT)
- Trial name
- [PEOPLE] (NCT06705257)
- Testing
- Studying the effects of varying levels of PEEP using Electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Acute Respiratory Distress Syndrome
Effect of Spontaneous Breathing in APRV Mode on Respiratory Physiology of ARDS Patients
This is a single-center, prospective, randomized, three-period crossover physiological study in adult patients with moderate-to-severe acute respiratory distress syndrome (ARDS, PaO₂/FiO₂ ≤150 mmHg).
- Trial name
- SBA-APRV (NCT07798154)
- Testing
- APRV ventilation with low-level spontaneous breathing, APRV ventilation with high-level spontaneous breathing, APRV ventilation with fully suppressed spontaneous breathing
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology