Clinical trials: Electrical Stimulation of the Brain
Stroke, Ischemic
Sensory Versus Motor Level Neuromuscular Electrical Stimulation
Dysphagia is a serious cause of morbidity and mortality in stroke survivors. Electrical stimulation is often included as part of the treatment plan for dysphagia, and can be applied at a sensory or motor level intensity.
- Trial name
- NMES (NCT05102877)
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Dysphagia, Oropharyngeal, Stroke, Ischemic
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
This study will evaluate the effectiveness of conventional speech therapy associated with functional electrical stimulation in patients with dysphagia after ischemic stroke.
- Trial name
- NCT03649295
- Testing
- Functional Electrical Stimulation, Conventional Speech Therapy
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Hospital Geral de Fortaleza
Stroke
Effects of BIONESS in Rehabilitation of Stroke
A four-weeks randomized clinical two-period crossover-design study will be conducted. Each patient will be randomized in a two separate consecutive treatment periods (Parallel Group Design).
- Trial name
- EFES-BIO-SEP (NCT04767360)
- Testing
- Bioness-300
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- LMU Klinikum
Alzheimer's Disease
Chronic Electrical Stimulation of Hypothalamus/Fornix in Alzheimer's Disease
Alzheimer's Disease (AD) is the most common cause of dementia for which no treatment has shown consistent efficacy to stop or slow down the disease.
- Trial name
- NCT00888056
- Testing
- Bilateral chronic electrical stimulation of the hypothalamus/fornix
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Alzheimer Disease
Digital Twins for Model-driven Non-invasive Electrical Brain Stimulation
The purpose of this study is to obtain preliminary data in advance of a larger clinical trial designed to test whether repeated, daily sessions of at-home transcranial alternating current stimulation (tACS) can lead to a…
- Trial name
- NEUROTWIN (NCT06826261)
- Testing
- transcranial alternating current stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke, Spinal Cord Injuries
Grasping Rehabilitation With Functional Electrical Stimulation Garment
This study tests the feasibility, safety and efficacy of garments embedding conductive electrodes (FES-shirt) for the independent delivery of functional electrical stimulation (FES).
- Trial name
- GarmentGrasp (NCT03658798)
- Testing
- Functional Electrical Stimulation
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Milos Popovic
Hemiplegic Shoulder Pain
Comparison of Effectiveness of Low Dose Laser and Transcutaneous Electrical Stimulation in Hemiplegic Shoulder
The primary aim of this study is to compare the efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) and Low Level Laser Therapy (LLLT), which are analgesic modalities that play an important role in the treatment of…
- Trial name
- NCT07203222
- Testing
- Low Dose Laser, TENS, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Schizophrenia, Cognitive Impairment
Electrical Brain Stimulation for Cognitive Impairment in Schizophrenia: a tDCS-fMRI Study
The purpose of this study is to investigate the mechanism of action of transcranial electrical brain stimulation over the dorsolateral prefrontal cortex for cognitive impairment in schizophrenia.
- Trial name
- NCT05200962
- Testing
- transcranial direct current stimulation
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Strokes Thrombotic
Efficacy of the Theta Burst Stimulation and Functional Electrical Stimulation in Stroke Rehabilitation
Approximately 50% of patients have persistent motor disability following stroke. Current treatment approaches with conventional physiotherapy have limited efficacy.
- Trial name
- NCT03555474
- Testing
- Theta burst stimulation, Functional Electrical Stimulation, Physiotherapy
- Volunteers
- 60 people
- Sponsor
- Sree Chitra Tirunal Institute for Medical Sciences & Technology
Schizophrenia
The Effects of tDCS on Illness Awareness in Schizophrenia
This is a novel study that seeks to explore the clinical and functional imaging effects of transcranial direct current stimulation (tDCS) on illness awareness or anosognosia in schizophrenia, arguably the most treatment-resistant…
- Trial name
- NCT02848885
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Centre for Addiction and Mental Health
Cerebral Palsy
The Effect of Functional Electrical Stimulation on Gait and Balance in Children With Hemiplegic Cerebral Palsy
The aim of this study will be to evaluate the effect of FES on stimulation of the anterior tibial group by using the WalkAide foot drop stimulator on improving walking and balance abilities in children with hemiplegic CP.
- Trial name
- NCT04269798
- Testing
- Traditional Treatment
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Acquired Brain Injury (Including Stroke)
Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.
This study aims to evaluate the effectiveness of physiotherapy treatment combined with functional electrical stimulation (FES) in a small group of patients with severe acquired brain injury (SABI) of vascular origin and with a…
- Trial name
- RISE (NCT07130929)
- Testing
- Functional Electrical Stimulation, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke
tDCS Immediate Effect on Cardiorespiratory Parameters in Hemiparetics Adults Patients Due to Stroke.
Previous studies found important function of brain in exercises regulation on healthy and athlete patients and this studies showed not invasive stimulation on temporal cortex brain, induces electrics field to insula cortex, in…
- Trial name
- NCT02398344
- Testing
- tDCS active
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Nove de Julho
Rest Tremor, Parkinson's Disease
The Study of Rest Tremor Suppression by Using Electrical Muscle Stimulation
This study is aimed to study the safety and feasibility of electrical muscle stimulation (EMS) in suppression of tremor from various causes especially for rest tremor in Parkinson's disease.
- Trial name
- NCT02370108
- Testing
- electrical muscle stimulation
- Volunteers
- 60 people
- Sponsor
- Chulalongkorn University
Stroke, Arm Motor Recovery
Repetitive Arm Training + FES on Upper Extremity Motor Recovery in Sub-acute Stroke Survivors
Rehabilitation restores functions and reduces disabilities due to diseases sequelae. The relationship between intensity of rehabilitation and clinical outcomes, recently emphasized, has generated a great interest for…
- Trial name
- NCT02267798
- Testing
- conventional therapy, arm training combined with FES
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- University Hospital of Ferrara
Memory Impairment
The Effect of tES on a Cognitive Training
The aim of this study is to investigate the effect of a transcranial electrical stimulation (tES) on a cognitive training in healthy elderly and memory impaired participants.
- Trial name
- NCT03475446
- Testing
- real anodal tDCS healthy elderly, real tACS healthy elderly, real anodal tDCS MCI
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Bern
Stroke, Spastic Hemiplegia
Effects of Neuromuscular Electrical Stimulation on Flexor Spasticity and Function in Stroke Patients
In this study, the investigators aimed to determine the effects of botulinum neurotoxin type A injections for wrist and finger flexor spasticity and neuromuscular electrical stimulation therapy applied to wrist and finger flexors…
- Trial name
- NCT06725069
- Testing
- Neuromuscular Electrical Stimulation, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Changes in EEG During and After Magnetic Stimulation
The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
The proposed study is designed to determine whether small changes in the positioning of a transcranial magnetic stimulation coil over the frontal parts of the brain cause different patterns of brain activation measured by…
- Trial name
- ERP (NCT01369264)
- Testing
- true left high frequency
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Refractory Epilepsy, Neuromodulation
Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG
The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy.
- Trial name
- NCT07305311
- Testing
- SEEG recordings and SPES
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Migraine
Compare the Effectiveness of nVNS and TENS on Pain and Quality of Life in Patients of Migraine
Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headaches, typically unilateral and frequently accompanied by nausea and heightened sensitivity to light and…
- Trial name
- NCT07055776
- Testing
- non-invasive vagus nerve stimulation (nVNS), non-invasive transcutaneous electrical nerve stimulation (TENS)
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Superior University