Clinical trials: Electrical Stimulation of the Brain
Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis
Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
This single-arm pilot study evaluates the effects of whole-body electrical muscle stimulation (WB-EMS) exercise on neuromuscular and physical function in adults with neuromuscular disease (NMD).
- Conditions
- Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Lambert-eaton Myasthenic Syndrome
- Trial name
- NCT07478172
- Testing
- Whole-body Electrical Muscle Stimulation Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri-Columbia
Dysphagia
Assess the Safety and Efficacy of the 4 Channel NMES, Pilot Study
This study is a pilot study to prepare clinical trials to evaluate the safety and effectiveness of 4-channel electric stimulation therapy devices as a newly developed function for the treatment of dysphagia disorders.
- Trial name
- NCT03664479
- Testing
- 4 channel Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Deglutition Disorders, Stroke
Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia
Prospective, randomized, controlled, three-arm, open-label, blinded analysis. Patients admitted with stroke diagnosis and with suspected dysphagia that meet the initial inclusion and exclusion criteria will be consented into the…
- Trial name
- VITAL (NCT02379182)
- Testing
- standard clinical care, transcutaneous electrical stimulation at sensory level, transcutaneous electrical stimulation at motor level
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Pere Clave
Stroke
Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke Patients
RATIONALE: The previous study resulted that the gait training using Functional Electrical Stimulation (FES) improved the ankle joint function and the walking ability for the chronic stroke patients with foot drop.
- Trial name
- PLEASURE (NCT02897752)
- Testing
- gait training with WA, usual gait training
- Where
- 24 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Stroke
Functional Electrical Stimulation Therapy After Stroke
The goal of this feasibility study is to test the feasibility of providing task-oriented, intention-driven functional electrical stimulation (FES) using the novel NeuroLife FES Sleeve and NeuroLife electromyography (EMG) and FES…
- Trial name
- NCT06207240
- Testing
- NeuroLife FES Sleeve / NeuroLife EMG-FES Sleeve
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Battelle Memorial Institute
Parkinson Disease
Investigating the Safety of srTMS in the Treatment of Parkinson's Disease
Super rapid transcranial magnetic stimulation (srTMS) is a method of brain stimulation that may be able to change the electrical activity of the nerve cells of the brain.
- Trial name
- NCT00063284
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
High-definition Transcranial Electrical Stimulation for Lower Limb Stroke Rehabilitation
Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct current or alternating current to change the excitability of the cerebral cortex.
- Trial name
- NCT04515121
- Testing
- HD-tCES, Lower limb rehabilitation
- Where
- 3 sites in Taiwan
- Volunteers
- 48 people
- Sponsor
- Taipei Medical University Hospital
Epilepsy
Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy
Patients with drug-refractory epilepsy sometimes need to be implanted with intracerebral electrodes in order to identify their seizure onset zone.
- Trial name
- StiMiC (NCT03738072)
- Testing
- StiMiC stimulation condition
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Parkinson Disease
Evaluation of the Safety of Electrical Spinal Cord Stimulation in Parkinson's Patients Presenting With Painful Camptocormia
Camptocormia is defined by abnormal flexion of the trunk, not fixed, present when standing and walking, resolves when lying down and often complicated by lower back pain.
- Trial name
- CAMPTOSTIM (NCT06291051)
- Testing
- Electrical spinal cord stimulation
- Where
- 4 sites in France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Rouen
Stroke, Swallowing Disorder
The Effects of Neuromuscular Electrical Stimulation on Swallowing Functions in Stroke Patients With Dysphagia
In our study, our aim is to evaluate the effect of neuromuscular electrical stimulation added to traditional dysphagia therapy in stroke patients with dysphagia, on functional oral intake status, dysphagia-related symptoms…
- Conditions
- Stroke, Swallowing Disorder, Dysphagia, Stroke, Complication
- Trial name
- NCT04421937
- Testing
- Procedure: Traditional Dysphagia Therapy (TDT), Procedure: Neuromuscular Electrical Stimulation with TDT
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University
Parkinson Disease, Depressive Symptoms
Low Voltage Electrical Stimulation for Depression in Parkinson's Patients
The goal of this clinical trial is to determine the relative efficacy of fMRI model guided Transcranial Direct Current Stimulation (mgTDCS) in improving the depressive symptoms of patients with Parkinson's Disease (PD).
- Trial name
- LVESDIPP (NCT06467695)
- Testing
- BIOPAC Stimsola
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Alabama
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Adults (Male and Female Subjects) With Tobacco Dependence
Direct Transcranial Electrical Stimulation in Tobacco Addiction (tDCS)
In summary, there are currently many therapeutic tools for achieving some degree of control or even cessation of tobacco addictive use.
- Trial name
- tDCS (NCT04209153)
- Testing
- Transcranial Direct Current Stimulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ischemic Stroke, Hemorrhagic Stroke
Effects of Transcranial Electrical Stimulation in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) with conventional physical therapy in sub-acute (at least 2 weeks after stroke onset) to chronic stroke within 2 years to investigate the effect on cortical…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Chronic Stroke, Subacute Stroke
- Trial name
- NCT06134921
- Testing
- transcranial direct current stimulation (Active), transcranial alternating current stimulation (active), Conventional physical therapy program
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Epilepsy
Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy
This study investigates the potential for temporally-interfering electric field stimulation (TIEFS) to treat epilepsy. In this case series within and between subjects design, the impact of TIEFS on epilepsy biomarkers was studied…
- Trial name
- EE-DES-TIEF (NCT06716866)
- Testing
- temporally-interfering electric field stimulation
- Where
- 3 sites in United States, Czechia
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Temporal Lobe Epilepsy
Electrical Brain Stimulation to Reduce Epileptic Seizures
OBJECTIVES: About 15% of patients suffering from focal epilepsy are refractory to available pharmacological treatments. Until now, the only hope for such patients has been the development of new pharmaceutical treatments or…
- Trial name
- NCT00344877
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Craniomandibular Disorders
Analgesic Effect of Cathodal tDCS Over Right DLPFC in Subjects With Muscular TMD: a Double Blind Crossover RCT
1. BACKGROUND: Temporomandibular Disorders (TMD) have become part of the daily routine of all the health care professionals. Some studies have shown improvement in subjects with chronic pain using neuromodulation.
- Trial name
- NCT02152267
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Federal University of Bahia
Dysphagia, Stroke
Investigation of the Effect of Neuromuscular Electrical Stimulation Techniques on Suprahyoid Muscles and Swallowing Function in Acute Hemiparetic Stroke Patients
This randomized controlled trial aims to investigate the effects of sensory, motor, and modified combined neuromuscular electrical stimulation (NMES) protocols on swallowing function in patients with acute stroke-related…
- Conditions
- Dysphagia, Stroke, Hemiparesis
- Trial name
- NMESWAL (NCT07445204)
- Testing
- Conventional Swallowing Therapy, Vitalstim-Sensory NMES, Vitalstim-Motor NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Arel University
Incomplete Spinal Cord Injury
Non-invasive Brain Stimulation Paired With FES Cycling Post SCI
This project is randomized controlled trial which will explore the effect of pairing repetitive Transcranial Magnetic Stimulation (rTMS) with Functional Electrical Stimulation (FES) Cycling on lower extremity function in people…
- Trial name
- NCT05975606
- Testing
- repetitive transcranial magnetic stimulation (rTMS), functional electrical stimulation (FES) cycling
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Western University, Canada
Alzheimer Disease, Electric Stimulation Therapy
Clinical Exploratory Research of Medial Prefrontal Cortex Combined With Dorsolateral Prefrontal Cortex Electrical Stimulation in the Treatment of Alzheimer's Disease
Alzheimer's disease (AD) is a common neurodegenerative disease characterized by progressive cognitive impairment and memory impairment, and is also a major cause of global dementia, characterized by progressive decline in memory…
- Trial name
- CBS-m/dlPFC-AD (NCT05971030)
- Testing
- Cortical brain stimulation of mPFC and dlPFC
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Xuanwu Hospital, Beijing