Clinical trials: Electrical Stimulation of the Brain
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Alzheimer Disease
Deep Brain Stimulation (DBS) for Alzheimer's Disease
Background: Alzheimer disease (AD) is a debilitating brain disorder that affects over 4.75 million people in the US and Canada. People with AD have difficulty remembering general facts and previously experienced autobiographical…
- Trial name
- NCT00658125
- Testing
- Bilateral fornix DBS implantation,
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Depression
Electrical Stimulation of the Internal Capsule for Intractable Depression
This study will evaluate the safety and efficacy of deep brain stimulation in treating people with several and otherwise treatment-resistant depression.
- Trial name
- NCT01069952
- Testing
- Deep Brain Stimulation System
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Butler Hospital
Alcohol Use Disorder
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol
The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at…
- Trial name
- tACS-MI (NCT04770025)
- Testing
- High-density transcranial alternating current stimulation, Motivational interviewing
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Traumatic Brain Injury
Application of Trans Cranial Direct Current Stimulation for Executive Dysfunction After Traumatic Brain Injury
Traumatic brain injury (TBI) particularly affects the frontal lobes and patients often suffer from executive dysfunction and behavioral disturbances.
- Trial name
- NCT02331615
- Testing
- neuroConn_CE_DC-STIMULATOR
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Loewenstein Hospital
Cerebral Palsy
The Effect of a Comprehensive Rehabilitation Program Using Robotic Walking and Functional Electrical Stimulation Technologies on Balance and Walking in Children With Cerebral Palsy
The aim of this study was to investigate the effect of a comprehensive rehabilitation program using robotic walking and functional electrical stimulation technologies on balance and gait in children with cerebral palsy.
- Trial name
- NCT06403891
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Spinocerebellar Atrophy (SCA)
The Investigation of the Pre-movement Facilitation of Agonist-antagonist Muscles and the Effect of the Feedforward Rehabilitation in Individuals With Hypermetria
In individuals with spino-cerebellar atrophy (SCA), the delayed onset of antagonist muscle firing has been reported to be the cause of hypermetria.
- Trial name
- NCT01983670
- Testing
- Temporal electrical stimulation
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Migraine
Peripheral Electrical Stimulation for Migraine Prevention
Migraine is a common and disabling disease that affects more than 10% of the population worldwide. The prevalence of migraine in Taiwan is around 9.1%.
- Trial name
- NCT03900611
- Testing
- peripheral electrical stimulation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Stroke
The Effect of Robotics-assisted Tilt Table and Functional Electrical Stimulation in Stroke Patients
Among subacute stroke patients (within 4 weeks after the onset), patients who are unable to walk are divided into experimental groups and control groups, and conventional rehabilitation treatment including physical therapy and…
- Trial name
- NCT04654793
- Testing
- Robot assisted inclined bed treatment and FES, conventional inclined bed treatment
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Stroke
Metrological Characteristics of the Inertial Unit "FOX HiKoB©" in Comparison With the Reference System for the Adaptive Trigger System "Functional Electrical Stimulation" of Foot Elevators in Hemiplegic Post-stroke Patients
The main objective of this study is to evaluate the metrological characteristics of the data processing algorithms from inertial sensors (FOX © HiKoB) for the reconstruction of movement relative to the reference system (VICON)…
- Trial name
- MASEA 2 (NCT02598154)
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Reflex Sympathetic Dystrophy of Upper Limb, Stroke
Peripheral Magnetic Stimulation to Treat Patient With Post-stroke Shoulder-hand Syndrome
Shoulder-hand syndrome is a common complication following stroke, constituting of excessive pain, swelling, heat, limited range of motion, and trophic change of the affected limbs.
- Trial name
- NCT05112094
- Testing
- peripheral magnetic stimulation, physical therapy
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Electrical Stimulation of the Brain
Effects of Direct Current Brain Stimulation on Cognition
This study will examine the effects of direct current (DC) electrical polarization of the brain on thinking speed, reaction time, mood, and brain waves in healthy individuals.
- Trial name
- NCT00048698
- Testing
- TMS, EEG
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Depression, Anxiety
Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders
The purpose of this research study is to determine whether Nexalin Trans-cranial Electrical Stimulation (TES) is a viable adjunctive treatment of substance use treatments.
- Conditions
- Depression, Anxiety, Insomnia, Substance Abuse
- Trial name
- NCT03540745
- Testing
- TES Treatment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Arizona
Neurogenic Dysphagia, Traumatic Brain Injury
Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia
Neurogenic dysphagia occurs with disruption of neurological systems or processes involved in the execution of coordinated and safe swallowing.
- Conditions
- Neurogenic Dysphagia, Traumatic Brain Injury, Stroke, Dysphagia
- Trial name
- R:IphEst (NCT05190718)
- Testing
- Pharyngeal electrostimulation
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Migraine, Migraine With or Without Aura
Evaluation of a Wearable Device for Acute Treatment of Migraines
The goal of this clinical trial is to determine the efficacy of a new, improved neuromodulation device that can be worn on the head and neck to relieve migraine pain.
- Conditions
- Migraine, Migraine With or Without Aura, Migraine, Acute, Migraine Headache
- Trial name
- NCT07015125
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Hinge Health, Inc
Cerebral Palsy
Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.
Background: Cerebral palsy (CP) is the most common motor disorder that affects children. People with CP have weak muscles; they may have trouble controlling the movements of their arms and legs.
- Trial name
- NCT06498596
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Dysphagia
Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing
Neuromuscular Electrical stimulation (NMES) for swallowing has recently been proposed for the treatment of dysphagia post stroke and is clinically receiving favor as a treatment modality, in the absence of strong research…
- Trial name
- ANSRS (NCT01279824)
- Testing
- swallowing therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Florida
Memory Disorders
Study of the Brain Stimulation Effect on Memory Impairment in Alzheimer Disease
Alzheimer's Disease (AD) is the most common cause of dementia. Today no treatment had shown consistent efficacy to stop or slow down the disease.
- Trial name
- NCT00947934
- Testing
- Deep brain stimulation
- Where
- 2 sites in France
- Sponsor
- Centre Hospitalier Universitaire de Nice