Clinical trials: Electrical Stimulation of the Brain
Vagus Nerve Diseases, Epilepsy
Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Electroceuticals is a new field in which the goal is to treat a wide variety of medical diseases with electrical stimulation of autonomic nerves.
- Conditions
- Vagus Nerve Diseases, Epilepsy, Vagus Nerve Autonomic Disorder
- Trial name
- EITsVNS (NCT05664854)
- Testing
- Nerve cuff electrodes for spatially selective vagus nerve stimulation and electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College, London
Stroke
Effects of Combined Neuromuscular Electrical Stimulation Robot and Trans-Spinal Electrical Stimulation in Poststroke Rehabilitation
The purpose of this study is to investigate the clinical efficacy and neurological progress of combined training using trans-spinal electrical stimulation (tsES) and neuromuscular electrical stimulation (NMES)-driven robotics on…
- Trial name
- NCT07112911
- Testing
- Electrical Stimulation; Rehabilitation Robot, Occupational Therapy with Electrical Stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 65 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Cognition Disorders
The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After Stroke
This clinical trial aims to investigate whether transcranial electrical stimulation (tDCS) combined with transcranial magnetic stimulation(TMS) has an impact on the cognitive and motor functions of stroke patients, and to…
- Trial name
- NCT07573475
- Testing
- occupational therapy, real tDCS, real TMS
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Ke Dong, MD
Stroke
Functional Eletrical Stimulation in Post Stroke Patients
The FES-ABLE project results from an Iberian partnership and aims to evaluate the impact of an intervention based on a functional electrical stimulation (FES) prototype on the upper limb movement quality during functional tasks.
- Trial name
- FES-ABLE (NCT03967613)
- Testing
- Functional eletrical stimulation
- Where
- Portugal
- Volunteers
- 14 people
- Sponsor
- School of Allied Health Sciences of Porto (ESTSP) - Polytechnic Institute of Porto (IPP)
Median Nerve, Coma
The Safety and Efficacy of Median Nerve Electrical Stimulation for Improving Neurological Function Prognosis in Patients With Cardiac Arrest
Median nerve stimulation (MNS), a non-invasive brain stimulation technique, has been widely adopted in clinical arousal therapies and multiple clinical investigations have attested to the efficacy of this technique; nevertheless…
- Conditions
- Median Nerve, Coma, Post Cardiac Arrest Brain Injury
- Trial name
- NCT06696690
- Testing
- MNS
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tang Ziren
Stroke, Broca's Aphasia
Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.
The primary objective of this feasibility study is to evaluate the safety and effectiveness of targeted sub-threshold epidural cortical stimulation delivered concurrent with speech-language rehabilitation activities to enhance…
- Trial name
- NCT00170703
- Testing
- Cortical Electrical Stimulation
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Northstar Neuroscience
Stroke, Foot Drop
Effect of FES Interventions on Gait Dynamics in Stroke Population
Our proposal quantitatively analyzes gait dynamics of hemiplegic individuals in response to the Function Electrical Stimulation (FES) intervention and identifies the responders to the intervention.
- Trial name
- NCT01952613
- Testing
- FES
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Schizophrenia; Negative Type
Deep Brain Stimulation (DBS) for the Management of Treatment Refractory Negative Symptoms in Schizophrenia
Schizophrenia is a complex, challenging, and heterogeneous psychiatric condition, affecting up to 0.5% of the population and responsible for nearly 2% of all Canadian health-care expenditure.
- Trial name
- NCT01725334
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Sponsor
- Centre for Addiction and Mental Health
Cerebrovascular Disorders, Healthy
Non-Invasive Electrical Stimulation of the Human Brain
This study is designed to allow researchers to use transelectrical stimulation to explore the function of the human nervous system and improve diagnosis of neurological disorders.
- Conditions
- Cerebrovascular Disorders, Healthy, Nervous System Diseases, Spinal Cord Injuries
- Trial name
- NCT00001216
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy (CP)
Effectiveness of NMES in Swallowing Rehabilitation in Children With CP
Purpose: The aim is to investigate the effectiveness of NMES in the functional and electrophysiological rehabilitation of swallowing difficulties in dysphagic children with cerebral palsy.
- Trial name
- NCT07329387
- Testing
- Neuromuscular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Necmettin Erbakan University
Post-Stroke Chronic Aphasia, Anomia (Word-retrieval Impairment)
Chronic Aphasia - Improved by Intensive Training and Electrical Brain Stimulation
The purpose of this study is to determine if non-invasive electrical brain stimulation can enhance the out of intensive language therapy in chronic aphasia
- Trial name
- CATS (NCT01221779)
- Testing
- Intensive language therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, Cramp
The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability
In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical…
- Conditions
- Stroke, Cramp, Restless Legs Syndrome, Healthy Volunteers
- Trial name
- MnHyperex (NCT05908214)
- Testing
- wide pulse high frequency neuromuscular electrical stimulation training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Cerebral Palsy (CP)
Neuromuscular Electrical Stimulation and Leap Motion-Based Exercises in Cerebral Palsy
Cerebral palsy (CP) is a group of disorders resulting from a permanent but non-progressive lesion in the developing brain, which affects the development of movement and posture and may lead to activity limitations.
- Trial name
- NCT07311018
- Testing
- Leap Motion-Based Exercise Program, NMES, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Stroke
Observation of the Gait Cycle in Patients With Hemiplegia in Order to Improve the Triggering of Functional Electrical Stimulation
The main objective of this study is the estimation and comparison of the dephasing between the switch heel and the inertial placed on the paretic foot compared to the events of the gait cycle determined by a Gaitrite system…
- Trial name
- MASEA (NCT01257646)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke
Enhanced Treadmill Gait Training With Lower Limb Support After Stroke
This series of single case studies aims to test the feasibility and acceptability of an enhanced treadmill system for the recovery of gait function in stroke survivors.
- Trial name
- ENTRES (NCT03348215)
- Testing
- Enhanced Treadmill Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Strathclyde
Acquired Brain Injury, Recovery of Function
Does Physiotherapy Plus Non-invasive Brain Stimulation Improve Motor Recovery in Children With Acquired Brain Injury?
The current study will evaluate the feasibility of transcranial direct current stimulation (tDCS) combined with an existing intensive physiotherapy program for children with ABI within the in/day-patient brain injury program at…
- Conditions
- Acquired Brain Injury, Recovery of Function, Transcranial Electrical Stimulation
- Trial name
- NCT04422886
- Testing
- active transcranial direct current stimulation (tDCS), Physiotherapy
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Stroke, Sensorimotor Impairment Affecting the Upper Limb
Effectiveness of Active Exploration of Simulated Textures for Sensorimotor Recovery
Parallel-group, single-blinded controlled clinical trial. The study includes people aged 18-80 years, more than one month after stroke, with confirmed diagnosis, MoCA ≥ 20, and Barthel Index ≥ 3.
- Conditions
- Stroke, Sensorimotor Impairment Affecting the Upper Limb, Sensory Deficit, Rehabilitation
- Trial name
- NCT06962397
- Testing
- Active Touch-Based Sensory Training
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Migraine Headache
Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches
This investigation will gather information about a procedure called sphenopalatine ganglion (SPG) stimulation, and its appropriateness, safety, and efficacy as a treatment for those who suffer migraine headaches which may result…
- Trial name
- NCT01294046
- Testing
- Deep Brain Stimulation of SPG for Migraine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Stroke
FES-Assisted Upper Extremity Ergometer Training in Subacute Stroke
Stroke is a leading cause of long-term disability and often results in impaired upper extremity function and reduced aerobic capacity. Improving both cardiovascular and function is an important goal in stroke rehabilitation.
- Trial name
- FES-UE-EX (NCT07484854)
- Testing
- Upper Extremity Ergometer Training, FES-Assisted Upper Extremity Ergometer Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Ischaemic Stroke
The RETRAIN Trial Phase 2
Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom.
- Trial name
- RETRAIN 2 (NCT07197996)
- Testing
- Intermittent Pneumatic Compression, geko® T3
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- Firstkind Ltd