Clinical trials: Electrical Stimulation of the Brain
Autism Spectrum Disorder
Electrical Brain Stimulation and Pharmacological Treatments in Autism Spectrum Disorder
This project aims to comparing the effectiveness of transcranial direct current stimulation with common pharmacological treatments on behavioral problems and cognitive deficits of children with autism spectrum disorder
- Trial name
- NCT05491720
- Testing
- RisperiDONE 1 MG/ML, transcranial direct current stimulation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Stroke, Aphasia
Improving Aphasia Using Electrical Brain Stimulation
Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a…
- Trial name
- NCT04963803
- Testing
- Active transcranial direct current stimulation (tDCS), Language Specific Attention Treatment
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Syracuse University
Cerebral Palsy, Spastic
The Effect of Task-oriented EMG-triggered ES on Upper Limb Motor Function in Hemiplegic Cerebral Palsy
The purpose of our study; to investigate the effects of EMG-induced ES treatment on hand functions, muscle strength, and quality of life in patients with hemiplegic CP.
- Trial name
- NCT04394819
- Testing
- electromyography-triggered electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- nihal tezel
Amblyopia
Transcorneal Electrical Stimulation (TES) for the Treatment of Amblyopia
This is a prospective, randomized, parallel group sham-controlled blinded clinical trial to assess the feasibility and efficacy of transcorneal electrical stimulation (TES) in the improvement of visual function outcomes in adults…
- Trial name
- NCT02495935
- Testing
- OkuStim®
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Pressure Injuries, Spinal Cord Injuries (SCI)
Electrical Stimulation for Clinical and Psychosocial Outcomes in Chronic Pressure Injuries
Pressure injuries are chronic wounds that frequently occur in immobilized patients and are associated with delayed healing, reduced quality of life, and significant psychological burden.
- Conditions
- Pressure Injuries, Spinal Cord Injuries (SCI), Traumatic Brain Injury
- Trial name
- NCT07493889
- Testing
- High-Voltage Monophasic Pulsed Current Electrical Stimulation, Standard Wound Care
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cervicogenic Headache, Occipital Neuralgia
The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain
The purpose of this study is to learn if pain can be relieved by delivering small amounts of electricity (called "electrical stimulation") to the nerves at the top of the neck.
- Trial name
- NCT05491915
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 50 people
- Sponsor
- SPR Therapeutics, Inc.
Acquired Brain Injury (Including Stroke), Spinal Cord Injury
Clinical Investigation to Validate the Safety and Performance of Integrating Functional Electrical Stimulation Into the ABLE Exoskeleton
The primary objective of this study is to validate the safety and clinical performance of the ABLE Exoskeleton with integrated Functional Electrical Stimulation (ABLE FES) in individuals with neurological conditions that impair…
- Conditions
- Acquired Brain Injury (Including Stroke), Spinal Cord Injury, Multiple Sclerosis
- Trial name
- NCT07550699
- Testing
- ABLE Exoskeleton with Functional Electrical Stimulation (ABLE FES)
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- ABLE Human Motion S.L.
Young Healthy Adults
Investigating the Mechanisms of Decision-Making Using Non-Invasive Brain Stimulation
This study aims to investigate which of two brain regions is important for which decision-making strategy. The investigators suppose that one brain region - the *striatum* - is important for repeatedly choosing objects that have…
- Trial name
- StimMaps_YH (NCT07749378)
- Testing
- Hippocampal intermittent-theta burst stimulation, Striatal intermittent-theta burst stimulation, High-frequency control stimulation with striatal electrode set-up
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Stroke, Cerebrovascular, Hemiplegia and Hemiparesis
BCI Driving FES and Hand Orthosis for Upper Limb Rehabilitation in Chronic Stroke
Multi-center, randomized, sham-controlled, double-blind, longitudinal, experimental clinical study to investigate functional recovery effects on the upper limb in chronic stroke patients and the accompanying neural plasticity…
- Conditions
- Stroke, Cerebrovascular, Hemiplegia and Hemiparesis, Stroke/Brain Attack
- Trial name
- NCT06179745
- Testing
- EEG-based brain-computer interface, Functional Electrical Stimulation, Active hand orthosis
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Essex
Effect of tDCS on Memory in Older and Younger Adults
Effect of Noninvasive Electrical Brain Stimulation on Memory at Different Times of Day in Younger and Older Adults
This study will investigate the extent to which tDCS to dorsolateral prefrontal cortex (or dlPFC) impacts memory performance as a function of time-of-day in younger and older adults.
- Trial name
- NCT03723850
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Parkinson's Disease
Electrical Stimulation for the Relief of Freezing of Gait (FOG) in Parkinson's Patients
Potential for electrical stimulation to ameliorate Freezing of Gait (FOG)
- Trial name
- NCT01970891
- Testing
- neuromuscular stimulation device
- Where
- Ireland
- Volunteers
- 12 people
- Sponsor
- National University of Ireland, Galway, Ireland
Insomnia, Sleep Deprivation
Study of the Effects of HIRREM-SOP for Insomnia
Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia.
- Trial name
- NCT03607994
- Testing
- HIRREM-SOP, NCC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Complex Regional Pain Syndrome I of Upper Limb, Pain
THE EFFECTS OF FUNCTIONAL ELECTRICAL STIMULATION-ASSISTED BICYCLE ERGOMETRY IN PATIENTS DIAGNOSED WITH COMPLEX REGIONAL PAIN SYNDROME.(CRPS)
The goal of this clinical study is to evaluate the effectiveness of functional electrical stimulation (FES)-assisted cycling in patients with post-stroke Complex Regional Pain Syndrome (CRPS) Type 1.
- Trial name
- CRPS (NCT07570199)
- Testing
- Functional Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zeynep Nur Köseoğlu
Stroke
Effectiveness of Functional Electric Stimulation With Bicycle Ergometer and Mirror Therapy in Stroke Patients Lower Extremity
There are different methods in stroke rehabilitation. In addition to conventional techniques, functional electric stimulation with bicycle ergometer therapy and mirror therapy can be used.
- Trial name
- NCT06558721
- Testing
- Conventional rehabilitation, Mirror therapy, Bicycle ergometer with functional electric stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Multiple Sclerosis
Transcranial Electrical Stimulation in Multiple Sclerosis
First the investigators will examine if the blood flow in the brain is different in patients with Multiple Sclerosis compared to healthy volunteers. HOW? The blood flow of the subjects is imaged by use of a special MRI-technique.
- Trial name
- TEMS (NCT06966128)
- Testing
- transcranial Direct Current Stimulation
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant
NESBID: Neuro-Stimulation of the Brain in Depression
In Canada, approximately 20% of patients with Major Depressive Disorder (MDD) have treatment-resistance and fail to respond to trials of pharmacotherapy or psychotherapy.
- Conditions
- Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant, Transcranial Direct Current Stimulation, Electric Stimulation Therapy
- Trial name
- NESBID (NCT04159012)
- Testing
- Transcranial direct current stimulation
- Where
- Canada
- Sponsor
- University of Alberta
Major Depressive Disorder
Deep Brain Stimulation in Treatment Refractory Depression
The main aim of this trial was to investigate whether patients suffering from treatment refractory- Major Depressive Disorder (MDD) can benefit from DBS (Deep Brain Stimulation) in the brain areas known as inferior thalamic…
- Trial name
- DBSTRD (NCT01921543)
- Testing
- ITP Stimulation, CI/BNST stimulation, No stimulation
- Where
- Belgium
- Volunteers
- 7 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Mild Cognitive Impairment, Alzheimer Disease
Using Exercise and Electrical Brain Stimulation to Improve Memory in Dementia
Mild cognitive impairment and Alzheimer's disease are conditions that involve memory difficulties. Transcranial direct current stimulation is a type of brain stimulation. It may help improve these memory difficulties.
- Trial name
- EXACT (NCT03670615)
- Testing
- tDCS, Exercise, Exercise Education
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Parkinson Disease
Electrical Vestibular Nerve Stimulation (VeNS) in the Management of Parkinson's Disease
Parkinson's disease burdens an increasing number of elderly populations in the country. Parkinson disease is a chronic, progressive neurodegenerative disorder, affects approximately 1% of the population by the age of 65 years and…
- Trial name
- NCT04450550
- Testing
- VeNS device
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Real HD-tDCS, Sham HD-tDCS
Determining the Specificity of High Definition Electrical Brain Stimulation Using Simultaneous Magnetoencephalography
Non-invasive human brain stimulation using weak transcranial direct-current stimulation (tDCS) has been thousands of times in research studies over the past fifteen years as a therapy to help improve the effectiveness of repeated…
- Conditions
- Real HD-tDCS, Sham HD-tDCS, Visual Task, Motor Task
- Trial name
- NCT02060708
- Testing
- HD-tDCS
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children