Clinical trials: Electrical Stimulation of the Brain
Stroke, Infarction; Posterior Cerebral Artery
Restoration of Vision After Stroke
Occipital stroke is associated with homonymous visual field defects (occurring on one side of the visual field). Despite spontaneous recovery, some degree of defect is often permanent.
- Conditions
- Stroke, Infarction; Posterior Cerebral Artery, Hemianopsia
- Trial name
- REVIS (NCT02405143)
- Testing
- Active tACS using DC-Stimulator MC
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Helsinki University Central Hospital
Dementia
Investigating Different Frequencies of Transcranial Electrical Stimulations in Dementia Population
Dementia is a prevalent condition with no known cure. It affects not only the person with dementia but also the family. This study will investigate the effects of applying different transcranial electrical stimulation (tES)…
- Trial name
- NCT06547021
- Testing
- Transcranial Direct Current Stimulation (tDCS), Gamma Transcranial Alternating Current Stimulation (tACS), Theta Transcranial Alternating Current Stimulation (tACS)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Stroke
Early Electrical Stimulation to Prevent Complications in the Arm Post-stroke - a Feasibility Study
Stroke is the largest cause of adult disability in the United Kingdom. Loss of hand function, muscle weakness, pain, and joint deformities are persistent and disabling problems for nearly half of all stroke survivors.
- Trial name
- ESCAPS (NCT02324634)
- Testing
- NeuroTrac Rehab dual channel device
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Transcranial Direct Current Stimulation (tDCS), Ageing
Investigating the Effectiveness of a 2-week Novel Non-invasive Brain Stimulation Technique on Cognitive Outcomes in Healthy Adults
The goal of this randomised controlled trial is to investigate the effects of a 2-week high-frequency transcranial pulsed current stimulation (tPCS) on cognitive outcomes in older and healthy adults.
- Conditions
- Transcranial Direct Current Stimulation (tDCS), Ageing, Executive Functioning, Transcranial Electric Stimulation
- Trial name
- NCT06991764
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Transcutaneous Vagal Nerve Stimulation (tVNS), Parkinson Disease (PD)
Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s Disease
This study aims to determine whether electrical stimulation of the ear, when combined with physical and speech therapy, can improve symptoms in subjects diagnosed with Parkinson´s disease, by comparing two different application…
- Trial name
- tVNS_PD (NCT07588191)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) of Vagus Nerve, Conventional Physical therapy, Conventional Speech Therapy
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidade da Coruña
Tinnitus
Impact of Neurostimulation on Patterns of Brain Electrical Activity in Patients With Tinnitus
Relating the electroencephalogram findings of patients with tinnitus before and after a therapeutic modality is still scarce in the literature, especially with neuromodulatory methods, more specifically with Transcranial Direct…
- Trial name
- NCT03036137
- Testing
- Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Migraine Disorders
Optimized tDCS for the Treatment of Migraine
The aim of this study is to establish an optimized protocol of tDCS that normalize the lack of habituation and efficiency of inhibitory cortical circuits in migraine patients and determine tDCS polarity and the best cortical…
- Trial name
- NCT02562222
- Testing
- anodal tDCS on M1, cathodal tDCS on M1, anodal tDCS on V1
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Cognitive Impairment After Brain Injury
The Study of Ginkgo Leaf Dropping Pills and Huperzine A Injection Combined With Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain Injury
This study will conduct a single-center clinical trial to explore the initial therapeutic effect of ginkgo biloba dropping pills, huperzine A injection and median nerve electrical stimulation in patients with cognitive impairment.
- Trial name
- NCT06704334
- Testing
- Median nerve electrical stimulation treatment, Huperzine A injection, Ginkgo leaf dropping pill
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wanbangde Pharmaceutical Group Co., LTD
Obsessive-Compulsive Disorder
Electrical Stimulation of the Internal Capsule for Intractable Obsessive-compulsive Disorder (OCD)
This study will evaluate the safety and effectiveness of deep brain stimulation in treating people with severe and otherwise treatment-resistant obsessive-compulsive disorder.
- Trial name
- NCT01061983
- Testing
- Medtronic Activa Deep Brain Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Butler Hospital
Parkinson Disease, Essential Tremor
Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (DBS) Devices With Conventional Surgery
The deep brain stimulation is surgical technique used for the Parkinson's disease, essential tremor, dystonia, epilepsy, and psychiatric diseases.
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia, Epilepsy
- Trial name
- NCT05535556
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Health Personnel, Stress
Cereset Research In Healthcare Workers During COVID-19
The purpose of this study is to evaluate the use of Cereset Research to improve the symptoms of stress in healthcare workers in an open label, waitlist controlled pilot clinical trial, during the period of COVID-19.
- Conditions
- Health Personnel, Stress, Anxiety, Insomnia
- Trial name
- NCT04682197
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Depression
Magnetic Brain Stimulation for the Treatment of Adult Depression
This study will evaluate the safety and effectiveness of magnetic brain stimulation for the treatment of major depression in depressed adults with moderate treatment resistance.
- Trial name
- NCT00149838
- Testing
- Prefrontal rTMS, Antidepressant Regimen
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- Medical University of South Carolina
Spinal Cord Injuries, Brain Injuries
Pilot Study for Peripheral Neuromuscular Electrical Stimulation of the Quadriceps Muscle
Feasibility study of a new medical device that will evaluate the usability and effectiveness of a cycle ergometer device associated with neuromuscular electrical stimulation (FES cycling).
- Conditions
- Spinal Cord Injuries, Brain Injuries, Muscle Atrophy
- Trial name
- NCT05888714
- Testing
- Experimental FES cycling, Comparator FES cycling, Conventional physical therapy
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson Disease
The Use of Sensory or Motor Cues Using Electrical Stimulation to Reduce Gait Freezing in Patients With Parkinson Disease
Some individuals with Parkinson disease experience "freezing" during walking which results in their inability to move their feet. They often have difficulty starting to move once they have stopped.
- Trial name
- NCT00762814
- Testing
- Gait tests with and without the use of a tactile sensory cue (electrical stimulation using a TENS unit)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Parkinson Disease
Continuous Electrical Neuromodulation of the Globus Pallidus Intern in Parkinson's Disease by the Directional Electrode CARTESIA™
Many patients have benefited from the implantation of brain stimulation electrodes for the treatment of various motor signs of Parkinson's disease in the phase of motor fluctuations.
- Trial name
- NEC-Parkinson (NCT05626608)
- Testing
- Classical ring stimulation, Stimulation in directional mode
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Parkinson' Disease
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on…
- Trial name
- ExtDCSPARK (NCT07524400)
- Testing
- real tDCS and exercise, Exercise
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Cerebral Palsy Children, Healthy Adults
Evaluating the Effects of an Electrical Stimulator on Improving the Walking Ability of Children With Cerebral Palsy
The goal of this study is to see if gentle electrical stimulation can help children with cerebral palsy (CP) walk more easily. This stimulation, called neuromuscular electrical stimulation (NMES), sends small pulses to muscles to…
- Trial name
- CP (NCT06811545)
- Testing
- Neuromuscular Electrical Stimulation (NMES)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hypotension Symptomatic, Parkinson's Disease
Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease
The PD-HemON study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to support hemodynamic management in people with typical and atypical Parkinson's Disease, who suffer…
- Conditions
- Hypotension Symptomatic, Parkinson's Disease, Orthostatic Hypotension, Dysautonomic, Multiple System Atrophy (MSA) With Orthostatic Hypotension
- Trial name
- PD-HemON (NCT06920134)
- Testing
- ARC-IM Investigational System
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Hemiplegia, Stroke, Acute
Effects Of Sensory Training and Electrical Stimulation on Sole of The Foot Sensations in Patients With Acute Hemiplegia
The aim of this study is to investigate the effects of the sole of foot sensory education and electrical stimulation on proprioceptive and cortical senses in patients with acute hemiplegia.
- Conditions
- Hemiplegia, Stroke, Acute, Sensory Disorders
- Trial name
- NCT04252092
- Testing
- Sensory training, Electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Binge-Eating Disorder
Ameliorating Cognitive Control in Binge Eating Disorder
There is evidence that impairment of impulse regulation is involved in the development and maintenance of eating disorders, especially in Binge Eating Disorder (BED).
- Trial name
- ACCElect (NCT04572087)
- Testing
- Behavioral training and verum stimulation
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Prof. Dr. Katrin Giel