Clinical trials: Electrical Storm
Ventricular Arrythmia, Ventricular Tachycardia
GANGlion Stellate Block for Treatment of Electric storRm (GANGSTER Trial)
This study will evaluate the acute effect of ultrasound-navigated left ganglion stellate block to suppress ventricular arrhythmia in patients with arrhythmic storm.
- Conditions
- Ventricular Arrythmia, Ventricular Tachycardia, Ventricular Fibrillation, Arrhythmic Storm
- Trial name
- GANGSTER (NCT05078684)
- Testing
- Left ganglion stellate block
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Cardiac Arrest
Beta-blockade With Landiolol in Out-of-hospital Cardiac Arrest
This study investigates the efficacy of landiolol versus placebo in patients with out-of-hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (electrical storm).
- Trial name
- Beta-Arrest (NCT05554978)
- Testing
- Landiolol, Sodium Chloride (NaCl) 0.9%
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Vienna
Ventricular Arrythmia, Cardiogenic Shock
Recurrent Ventricular Arrythmias in ICU
Electrical storm (ES) is a life-threatening syndrome defined by the recurrence of ventricular arrythmias. ES is also represented by a wide spectrum of clinical situations ranging from recurrent monomorphic VT reduced by…
- Conditions
- Ventricular Arrythmia, Cardiogenic Shock, Electrical Storm
- Trial name
- ElectStorm (NCT07033065)
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Arrhythmic Storm, Electrical Storm
In-hospital Stellate Ganglion Block for Arrhythmic Storm
Arrhythmic storm is a real emergency and its treatment could be challenging. Antiarrhythmic drugs are few and often ineffective.
- Conditions
- Arrhythmic Storm, Electrical Storm, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- STAR (NCT05720936)
- Testing
- Percutaneous stellate ganglion block (PSGB)
- Where
- 38 sites in Italy, Switzerland
- Volunteers
- 500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Ventricular Arrhythmias, Electrical Storm
Cardiac Sympathetic Denervation in Patients With Refractory Arrhythmic Storm: a Single-center Case Series
The objective of our study was to evaluate the effectiveness of stellate ganglion block (SGB) and of the bilateral cardiac sympathetic denervation (BCSD) in patients with electrical storm refractory to conventional treatment..
- Conditions
- Ventricular Arrhythmias, Electrical Storm, Stellate Ganglion Block
- Trial name
- NCT07375264
- Testing
- Cardiac sympathetic denervation.
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Jose Manuel López González
Electrical Storm, VT
Percutaneous Stellate Ganglion Block as First Line Treatment in Patients With Electrical Storm: the STAR 2 Study
Electrical storm (ES) is a life-threatening condition characterized by recurrent episodes of ventricular tachycardia (VT) or ventricular fibrillation (VF) requiring anti-tachycardia pacing or defibrillator shocks.
- Conditions
- Electrical Storm, VT, VF, Ventricular Arrhythmia
- Trial name
- STAR 2 (NCT07841080)
- Testing
- L-PSGB first
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Ventricular Tachycardias
Does Timing of VT Ablation Affect Prognosis in Patients With an Implantable Cardioverter-defibrillator?
The purpose of this study is to assess whether the burden of untreated non-sustained ventricular tachycardias (VTs), or episodes treated with anti-tachycardia pacing, correlates with appropriate implantable cardiac defibrillator…
- Trial name
- PARTITA (NCT01547208)
- Testing
- Immediate radiofrequency ablation of ventricular tachycardia, Radiofrequency ablation of ventricular tachycardia
- Where
- 21 sites in Belgium, Czechia and 5 more
- Volunteers
- 590 people
- Sponsor
- IRCCS San Raffaele
Ventricular Tachycardia, Ventricular Arrhythmias
Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm
The objective of this study is to determine if there is a meaningful benefit to using the sedative medication dexmedetomidine in the acute treatment of patients with recurrent ventricular arrhythmias, known as electrical storm.
- Conditions
- Ventricular Tachycardia, Ventricular Arrhythmias, Ventricular Fibrillation, Recurrent Ventricular Tachycardia
- Trial name
- SEDATE (NCT06281977)
- Testing
- Dexmedetomidine, Normal saline
- Where
- 2 sites in United States, Canada
- Volunteers
- 192 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Arrhythmias, Cardiac, Tachycardia, Ventricular
International Electrical Storm Registry
Organized ventricular arrhythmias (ventricular tachycardia (VT), torsades de pointes (TdP) and ventricular fibrillation (VF)) represent a major event in the clinical history of a patient and they can lead to hemodynamic…
- Conditions
- Arrhythmias, Cardiac, Tachycardia, Ventricular, Ventricular Fibrillation, Defibrillators, Implantable
- Trial name
- ELECTRA (NCT02882139)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Università Politecnica delle Marche
Ventricular Tachycardia
Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease
This is a multi-center, parallel-group, randomized, open-label trial evaluating the clinical outcome and efficacy of emergency catheter ablation versus conventional stepped-care strategies in patients with haemodynamically…
- Trial name
- NCT06455020
- Testing
- Catheter ablation, Stepped-care strategies
- Where
- 4 sites in China
- Volunteers
- 96 people
- Sponsor
- Beijing Anzhen Hospital
Electrical Storm, Stellate Ganglion Block
Percutaneous Blockade of the Stellate Ganglion in Electrical Storm
There is no randomized clinical study in the literature that evaluated the efficacy and safety of the stellate ganglion infiltration procedure in patients with electrical storm.
- Conditions
- Electrical Storm, Stellate Ganglion Block, Ventricular Arrhythmia
- Trial name
- NCT07211347
- Testing
- Stellate Ganglion Block
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Sao Paulo General Hospital
Heart Failure, Ventricular Tachycardia
Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation
Prevalence of HF reaches 1-2% of developed populations, and consequently a significant problem becomes more frequent occurrence of ventricular arrhythmias (VA) - sustained ventricular tachycardia (sVT) and electrical storm (ES)…
- Conditions
- Heart Failure, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- STORM (NCT02784912)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Ventricular Tachycardia (V-Tach) Storm
Stellate Ganglion Neuromodulation for the Treatment of Electrical Storm
Ventricular tachycardia (VT) is a serious heart rhythm problem in which the heart beats very fast and in an abnormal way. These abnormal heart rhythms can be life-threatening.
- Trial name
- STORM-OFF (NCT07857889)
- Testing
- Stellate Ganglion Block Injection with Bupivicaine
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Population Health Research Institute
Arrhythmias
Ventricular Tachyarrhythmia (VT) Storm, Gene Expression in Implantable Cardioverter Defibrillator (ICD) Patients With Electrical Storm
The purpose of the proposed pilot study is to identify factors which are associated with periods of high ventricular arrhythmia burden. This will be performed by analysis of gene expression from peripheral blood samples.
- Trial name
- NCT00284453
- Testing
- Peripheral blood sampling
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Pittsburgh
Mental Health
Mental Health After Dexmedetomidine for Electrical Storm
The goal of the research study is to measure mental health and quality of life indices of individuals treated for electrical storm (ES).
- Trial name
- NCT07368062
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ottawa Heart Institute Research Corporation