Clinical trials: Electrocochleography
Cochlear Hearing Loss, Cochlear Trauma
Using Electrocochleography During Cochlear Implantation of the Neuro Zti.
The main objective of this study is to evaluate the correspondence between eCochG and residual hearing by adding two modifications.
- Trial name
- PIC-22_eCoN (NCT04651660)
- Testing
- Neuro Cochlear Implant System
- Sponsor
- Oticon Medical
Cochlear Prosthesis Implantation
Electrocochleography Along Cochlear Implant Auditory Rehabilitation
Electrocochleography (eCochG) is an electrophysiological measurement to evaluate the activity of cochlear hair cells in response to acoustic stimulation.
- Trial name
- eCochGIC (NCT04561388)
- Testing
- Electrocochleography, Pure Tone Audiometry, Speech audiometry
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Sensorineural, Severe-to-profound Hearing Loss
Hearing and Structure Preservation Via ECochG
The goal of the study is to determine the benefit of using an ECochG-based corrective action guide during cochlear implant surgery compared to the traditional surgical approach without ECochG surveillance and guidance.
- Trial name
- PRESERVE (NCT06268340)
- Testing
- ECochG monitored CI surgery incl. corrective action guide, Routine CI surgery without ECochG monitoring
- Where
- 7 sites in Belgium, France and 5 more
- Volunteers
- 102 people
- Sponsor
- Advanced Bionics AG
Hearing Impairment, Sensorineural
Cochlear Response Telemetry and Hearing Preservation
The main purpose of this study is to monitor the response from the cochlea as the electrode is inserted during the operation to receive a cochlear implant.
- Trial name
- CREST (NCT03134989)
- Testing
- Cochlear implant
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Cochlear
Hearing Loss, Cochlear Implant
Cochlear Trauma, Functional and Structural Preservation in Cochlear Implant Surgery
Prospective 2-arm cohort consisting of a preoperative visit and visits at the time of implantation (Day 0) and follow-up in patients for whom their treating physician indicated a perimodiolar or straight cochlear implant.
- Conditions
- Hearing Loss, Cochlear Implant, Cochlear Microphonics, Electrocochleography
- Trial name
- NCT05079867
- Testing
- Cochlear implantation
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Italiano de Buenos Aires
Sensorineural Hearing Loss
Hearing Preservation in Cochlear Implantation Surgery
In order to preserve the residual hearing in patients with sensorineural hearing loss (SNHL) receiving a cochlear implant (CI), the insertion trauma to the delicate and microscopic structures of the cochlea needs to be minimized.
- Trial name
- CIPRES (NCT07146841)
- Testing
- Round window insertion, Cochleostomy insertion, Lateral wall array
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- UMC Utrecht
Vertigo, Meniere Disease
Effect of Stellate Ganglion Block on Meniere's Disease
Stellate ganglion block (SGB) has been the alternative treatment of Meniere's disease for years. However, objective evidence of the effect of SGB was still lack.
- Trial name
- NCT01574313
- Testing
- stellate ganglion block, 0.25mg, fludiazine, 25mg cephadol@ (diphenidol)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chi Mei Medical Hospital
Hearing Loss, Cochlear
Electrocochleography Function for Monitoring Residual Hearing
This trial is a pilot study to assess the feasibility of using Electrocochleography recorded from a cochlear implant intra-operatively in real time to monitor the progress of its insertion. Correlation between: 1.
- Trial name
- ECochG (NCT03848338)
- Testing
- Electrocochleography
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Vestibular Abnormality, Endolymphatic Hydrops
Effects of Infrasound Exposure on Measures of Endolymphatic Hydrops
Persons exposed to infrasound - frequencies below 20 Hz - describe a variety of troubling audiovestibular symptoms, but the underlying mechanisms are not understood.
- Trial name
- NCT03132961
- Testing
- Infrasound exposure
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cochlear Implants, Hearing Loss, Sensorineural
Clinical Trial to Compare Two Surgical Approaches to the Cochlea
This is a prospective multicenter multinational randomized control trial. The duration of the study for the individual patient will be approximately 1 year (pre-operative assessments, 1 week, 3 months and 12 months follow-up…
- Trial name
- BULLS-I (NCT06453343)
- Testing
- Surgical approach: cochleostomy or extended round window
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Healthy Volunteer, Without Hearing Disorders
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers
Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss".
- Trial name
- ECOG (NCT04198909)
- Testing
- Electrocochleography, electrophysiology thet for analyse the wave I generated by the auditory pathways
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sensorineural Hearing Loss, Bilateral Hearing Loss
Comparative Analysis of Hearing Outcomes: Robotic vs. Manual Insertion of Cochlear Implants
This research study is evaluating two different methods of cochlear implant (CI) insertion - robotic-assisted insertion and manual insertion - to better understand how they affect hearing outcomes.
- Conditions
- Sensorineural Hearing Loss, Bilateral Hearing Loss, Cochlear Implantation, Hearing Disorders
- Trial name
- NCT07081542
- Testing
- IotaSoft Robotic Insertion System, Manual Cochlear Implant Insertion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- AdventHealth
Fitting Methods by EAS Patients
Optimization and Validation of Electric Acoustic Stimulation (EAS) Mapping as a Function of Residual Hearing After CI-Implantation
The aim of this clinical study is to investigate how the fitting of an EAS (electrical acoustic stimulation) based on electrocochleography (ECochG) thresholds compares to fitting based on pure tone audiogram thresholds in terms…
- Trial name
- NCT07476079
- Testing
- The objective fitting method of the EAS based on the thresholds of electrocochleography is the intervention of our study., The subjective adjustment of an EAS based on thresholds from the pure tone audiogram.
- Volunteers
- 12 people
- Sponsor
- Luzerner Kantonsspital
Tinnitus
Tinnitus Treatment With Piribedil Guided by Acoustic Otoemissions and Electrocochleography
Tinnitus is defined as the perception of sound in the absence of a external source. About 15 % of the population is believed to experience tinnitus and for about 20 % of them it may become a very serious problem.
- Trial name
- piribedil (NCT00591994)
- Testing
- piribedil
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Faculdade de Medicina de Valenca