Clinical trials: Electroconvulsive Therapy Treated Patients
Major Depressive Disorder
Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients
Our hypothesis is that using antidepressants during the ECT has a better efficacy and longer time to relapse/recurrence to the ECT without antidepressants.
- Trial name
- NCT04181567
- Testing
- electroconvulsive therapy, agomelatine
- Where
- Taiwan
- Volunteers
- 97 people
- Sponsor
- Kaohsiung Kai-Suan Psychiatric Hospital
Idiopathic Parkinson's Disease, Multiple Sclerosis
Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy
In Parkinson's disease, Multiple Sclerosis and depressed patients treated with electroconvulsive therapy, cognitive dysfunction is prevalent. However, treatment of these dysfunctions is in its infancy.
- Conditions
- Idiopathic Parkinson's Disease, Multiple Sclerosis, Elderly Post Electric Convulsive Therapy
- Trial name
- NCT02525367
- Testing
- Online cognitive training, Active control condition
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Amsterdam UMC, location VUmc
Depressive Disorder, Major
Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder
Developing more effective and faster acting antidepressant is of outmost clinical importance. Available antidepressant therapies have a delayed therapeutic effect.
- Trial name
- NCT02659085
- Testing
- Ketamine IV Infusion, ECT
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Pouya Movahed Rad
Depressive Disorder
Memory Changes in Patients With Major Depression Disorder Treated With ECT
The basic memory changes (impairment) present in patients with major depression and the influence of the treatment with ECT.
- Trial name
- NCT03915821
- Testing
- ECT
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Electroconvulsive Therapy Treated Patients, Obesity
LMA vs High-flow Nasal Oxygen During ECT in Obese Patients
This study aims to compare two oxygenation strategies-laryngeal mask airway (LMA) ventilation and high-flow nasal cannula (HFNC)-during electroconvulsive therapy (ECT) in obese patients.
- Trial name
- NCT07093372
- Testing
- Laryngeal Mask Airway, High-Flow Nasal Cannula
- Volunteers
- 25 people
- Sponsor
- Eulji University Hospital
Anxiety State
Music Listening to Lower Anxiety During ECT Treatment.
The purpose of this study is to assess whether music listening is helpful in lowering anxiety in patients about to start their ECT treatment.
- Trial name
- MIECT (NCT04706728)
- Testing
- Listening to playlists with music prior to-, during and after the ECT procedure, Listening to playlists with sound from nature (rain, waves) prior to-, during and after the ECT procedure
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Aalborg University
Depressive Episode, Electroconvulsive Therapy
RCT for Electroconvulsive Treatment Followed by Cognitive Control Training
Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high.
- Conditions
- Depressive Episode, Electroconvulsive Therapy, Cognitive Remediation
- Trial name
- ECT-CCT (NCT05683028)
- Testing
- Cognitive Control Training, Active Control
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Ghent
Bipolar Depression
Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic
The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose LFR protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with bipolar…
- Trial name
- NCT04427137
- Testing
- MagPro X100 Stimulator, B70 Fluid-Cooled Coil
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia
Bifrontal and Bitemporal Electroconvulsive Therapy (ECT) in Treatment of Patients With Schizophrenia
Electroconvulsive therapy has been used in clinical practice since 1938, a number of randomized trials found significant differences favoring ECT in response rates between individuals with depression receiving real and sham ECT.
- Trial name
- ESBECT (NCT02511509)
- Testing
- Bifrontal electroconvulsive therapy, Bitemporal electroconvulsive therapy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Refractory Schizophrenia, Super Refractory Schizophrenia
Electroconvulsive Therapy (ECT) in Patients With Super Refractory Schizophrenia
Introduction: In spite of recent advances in schizophrenia treatment, 30% of patients still do not respond properly to antipsychotic therapy.
- Trial name
- SSURECT (NCT02049021)
- Testing
- MECTA SPECTRUM 5000Q ECT
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Major Depressive Disorder
Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant Depression
Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-resistant depression (TRD). However, due to response delay and cognitive impairment, ECT remains an imperfect treatment.
- Trial name
- STIMAGNECT2 (NCT06391723)
- Testing
- Active rTMS
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier du Rouvray
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Catatonia
Prospective Treatment Study of Catatonia Patients
The purpose of this treatment study is to compare the effectiveness of different electrode placements used in Electroconvulsive Therapy (ECT) in the treatment of catatonia.
- Trial name
- NCT02734498
- Testing
- Electroconvulsive Treatment (ECT) Right Unilateral, Electroconvulsive Treatment (ECT) - Bilateral
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
Music Intervention, Electroconvulsive Therapy Treated Patients
The Effect of a Music Intervention on Postictal Agitation in Electroconvulsive Therapy Patients
This study will investigate the effect of music on postictal agitation when played peri-interventionally for patients undergoing electroconvulsive therapy for severe depression.
- Conditions
- Music Intervention, Electroconvulsive Therapy Treated Patients, Agitation on Recovery From Sedation
- Trial name
- MUSE (NCT06817330)
- Testing
- Intervention group, listening to recorded music, Control group, headphones with no music
- Where
- 2 sites in Netherlands
- Volunteers
- 92 people
- Sponsor
- Erasmus Medical Center
Depression
Mifepristone Treatment for Patients With Non-psychotic Major Depressive Disorder Receiving Bilateral ECT
The purpose of this study is to see whether the medication mifepristone is an effective and tolerable treatment for increasing the clinical effectiveness of electroconvulsive therapy (ECT) and protecting cognitive function during…
- Trial name
- NCT00285818
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
Depressive Disorder, Major
Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA
Prospective observational cohort study to determine cost-effectiveness of ECT compared to medication in the treatment of major depressive disorder (MDD) in the Netherlands.
- Trial name
- PROSPECT (NCT05306184)
- Testing
- Electroconvulsive therapy (ECT)
- Where
- 2 sites in Netherlands
- Volunteers
- 220 people
- Sponsor
- Radboud University Medical Center
Intracranial Pressure Change, Hypertension
Optic Nerve Sheath Ultrasound During Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is an effective method that has been used for many years in the treatment of psychiatric disorders and is currently administered under general anesthesia.
- Conditions
- Intracranial Pressure Change, Hypertension, Electroconvulsive Therapy Treated Patients
- Trial name
- NCT06607679
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- İrem AKSOY
Severe Depression
Brain Changes in Severely Depressed Patients Before and After Treatment With Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is a non-pharmacological treatment used in resistant depression whose effectiveness has been demonstrated. However, the brain mechanisms underlying this therapeutic effect remain unclear.
- Trial name
- ECT-IM (NCT02715986)
- Testing
- 3T MRI
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Toulouse
Treatment Resistant Depression, Electroconvulsive Therapy
ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)
The goal of the study is to conduct a comparative randomized trial of electroconvulsive therapy (ECT) vs. ketamine for patients with treatment resistant depression (TRD) in a real world setting with patient reported outcomes as…
- Conditions
- Treatment Resistant Depression, Electroconvulsive Therapy, ECT, Ketamine
- Trial name
- ELEKT-D (NCT03113968)
- Testing
- electroconvulsive therapy (ECT), Ketamine
- Where
- 5 sites in United States
- Volunteers
- 403 people
- Sponsor
- Bo Hu
Depressive Episode, Electroconvulsive Therapy
Electroconvulsive Treatment Followed by Cognitive Control Training
Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high.
- Conditions
- Depressive Episode, Electroconvulsive Therapy, Cognitive Remediation
- Trial name
- ECT-CCT (NCT04383509)
- Testing
- Cognitive Control Training, Active Control
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Ghent