Clinical trials: Electronic Health Records
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Hypertension, Hyperlipidemia
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment…
- Conditions
- Hypertension, Hyperlipidemia, Diabetes, Smoking
- Trial name
- NCT01420016
- Testing
- Prioritized Clinical Decision Support
- Volunteers
- 7,914 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Diabetes Mellitus, Insulin Hypoglycemia
Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
This is a 24-week, open-label, randomized, multi-center trial conducted in three tertiary hospitals. There are three follow-up measures; at baseline, post-intervention at Week 12, and Week 24.
- Conditions
- Diabetes Mellitus, Insulin Hypoglycemia, Insulin-dependent Diabetes Mellitus
- Trial name
- ICT (NCT03112343)
- Testing
- Algorithm-based feedback messages, Personal Health Record
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Major Depressive Disorder
Electronic-Measurement Based Care for Major Depressive Disorder
The pilot study will evaluate whether electronic-Measurement Based Care (e-MBC) using the UT Southwestern MyChart personal health record is feasible, associated with patient and health care team satisfaction, and improves…
- Trial name
- e-MBC (NCT01583998)
- Testing
- e-MBC
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Cardiac Disease, Cancer
Electronic Medical Records and Genomics (eMERGE) Phase III
The Electronic Medical Records and Genomics (eMERGE) Network is in its third phase and during this time is enrolling and sequencing 25,000 individuals on a custom sequencing panel of clinically relevant, actionable genes.
- Conditions
- Cardiac Disease, Cancer, Hypercholesterolemia, Diabetes
- Trial name
- eMERGE (NCT03394859)
- Volunteers
- 25,380 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Acute Kidney Injury, Delirium
AKI and Delirium Risk Prediction and Cost Burden Study
The goal of this study is to learn how to better predict two common health problems that can happen during a hospital stay: acute kidney injury (AKI) and delirium. AKI is a sudden decline in kidney function.
- Trial name
- HAAKID (NCT07866560)
- Testing
- It is observational trial with no intervention being evaluated
- Where
- United States
- Volunteers
- 25,000 people
- Sponsor
- University of Nebraska
Hypertension, High Blood Pressure
Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults above age 30. The prevalence of hypertension, a major risk factor for CVD, is increasing over time in sub-Saharan Africa, exerting a…
- Trial name
- NCT01844596
- Testing
- behavioral communication strategy, Behavioral communication strategy, plus smartphone-based tool
- Where
- Kenya
- Volunteers
- 1,455 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hospital-acquired Infections
AI-Driven Prediction of Hospital-Acquired Infections With EHR
This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying and diagnosing infection, leveraging multimodal health data.
- Trial name
- NCT06791382
- Testing
- AI-Based Diagnostic and Prognostic Model
- Where
- 2 sites in China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Chlamydial Infections
Validation of Chlamydia Diagnostic Codes in TriNetX US EHR Data
This study is a pharmacoepidemiologic method study based on the secondary use of pre-existing data that examines whether TriNetX, a global health research network encompassing a worldwide electronic health record (EHR), database…
- Trial name
- NCT07094373
- Where
- United States
- Volunteers
- 4,878,935 people
- Sponsor
- Sanofi
Mobile Applications, Internet-Based Intervention
Evaluation of the Utility of Preanestes@s, a Web Based Application for Preoperative Assessment
In this prospective two-arm study, the investigators will evaluate the incidence of suboptimal preoperative assessments when the participants are evaluated through a web based application (Preanestes@s) versus the traditional…
- Conditions
- Mobile Applications, Internet-Based Intervention, Ambulatory Surgical Procedures, Preoperative Period
- Trial name
- Preanestes@s (NCT04787783)
- Testing
- Web based preoperative assessment
- Where
- Spain
- Volunteers
- 2,254 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Chronic Obstructive Pulmonary Disease (13645005)
Advancing the Patient Experience in Chronic Obstructive Pulmonary Disease (APEX COPD)
APEX COPD is registry to provide a mechanism to standardize, store and utilize data to enable greater power to answer key research questions, and to improve patient outcomes in COPD primary care.
- Trial name
- APEX COPD (NCT04285047)
- Testing
- Advancing Patient Experience (APEX) in COPD
- Where
- 4 sites in United States
- Volunteers
- 4,500 people
- Sponsor
- Optimum Patient Care
Secondary Immunodeficiency (SID)
A Study of Secondary Immunodeficiencies in Adults With Blood Cancers in Kazakhstan Who Have a Weakened Immune System (K-SIDE Study)
Some people with blood cancers (hematologic malignancies) develop a weakened immune system because of their condition or the medicines used to treat it. This is called a secondary immunodeficiency or SID.
- Trial name
- NCT07868107
- Testing
- No Intervention
- Where
- Kazakhstan
- Volunteers
- 200 people
- Sponsor
- Takeda
Heart Failure
Implementing Standards of Care for Heart Failure Patients in General Practice - A Regional Disease Management Program
Heart failure (HF) is an important health problem. Most chronic HF management occurs in primary care. Although guidelines exist, there is an important implementation gap in current HF care in Belgium.
- Trial name
- NCT04334447
- Testing
- Improved primary care HF diagnostics, Heart Failure education, Structured transitional protocol planning post-discharge care
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- KU Leuven
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Pregnant
Project HOPE 1000: Health Outcomes Pregnancy Exposures
The purpose of this study is to collect biological samples from pregnant women and their babies and to collect data on long-term health, school outcomes, and the use of state and county services.
- Trial name
- NCT04417283
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Duke University
Opioid Use Disorder, Opioid Misuse
Natural Language Processing for Screening Opioid Misuse
This is a clinical study to implement and evaluate a hospital-wide, operational intervention for a real-time natural language processing (NLP)-driven clinical decision support (CDS) tool, called Substance Misuse Algorithm for…
- Trial name
- NCT05745480
- Testing
- Opioid Misuse Screening with an Addiction Consult Service
- Where
- United States
- Volunteers
- 47,502 people
- Sponsor
- University of Wisconsin, Madison
Clinical Decision-Making, Decision Making, Computer-assisted
A Study to the Impact of Accuracy Problem Lists in Electronic Health Records on Correctness and Speed of Clinical Decision-making Performed by Dutch Healthcare Providers
The primary objective of this study is to determine whether patient records with complete, structured and up-to-date problem lists ('accurate problem lists'), result in better clinical decision-making, compared to patient records…
- Conditions
- Clinical Decision-Making, Decision Making, Computer-assisted, Medical Records, Problem-Oriented, Quality of Health Care
- Trial name
- ADAM's APPLE (NCT05657002)
- Testing
- patient A with accurate problem list, patient B with inaccurate problem list, patient A with inaccurate problem list
- Where
- Netherlands
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Eva Klappe
Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7
Patient Reported Outcomes, Smart Pill Bottle and Teleheath for Endocrine Therapy Adherence
This phase II trial studies how well telehealth works in improving adherence to endocrine (anti-estrogen) therapy in participants with estrogen receptor and/or progesterone receptor positive (hormone receptor positive) stage…
- Conditions
- Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
- Trial name
- NCT04054557
- Testing
- Telemedicine, Best Practice, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 305 people
- Sponsor
- Thomas Jefferson University
Attitude of Health Personnel
Educational Intervention to Increase Physician Satisfaction and Effectiveness With a New Electronic Health Record
This study was intended to test the effects of adding a one-on-one educational intervention taught by a physician to a physician during their clinical work to improve their acceptance and satisfaction with a new inpatient…
- Trial name
- NCT02015702
- Testing
- One-on-one physician training, Usual training
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Social Determinants of Health, Primary Care
DEDICATE: aDvancing carE Management aDoption In Community heAlTh cEnters
DEDICATE will refine and test the effectiveness of evidence-based implementation support strategies designed to support care management teams' sustained use of electronic health record (EHR)-based functionalities to address unmet…
- Conditions
- Social Determinants of Health, Primary Care, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- DEDICATE (NCT06489002)
- Testing
- Implementation Support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- OCHIN, Inc.