Clinical trials: Electrophysiology
Depression
rTMS and Cognitive Training in Youth Depression
Youth depression is a highly prevalent disorder with tremendous personal and societal costs. Guideline supported treatments are limited in efficacy and associated with side effects.
- Trial name
- NCT03708172
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cognitive Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Parkinson Disease
Neocortical Microarchitecture of Executive Function
This study is being done to the determine the ability and utility of using the Neuropixels probes in the human brain. A Neuropixels probe will be inserted into and removed from the brain of awake human patients who are undergoing…
- Trial name
- NCT06778135
- Testing
- Temporary implatation of large-scale intracranial electrode., brain electrode
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
Coma
Improving Awakening Prognostication After Non Anoxic Coma Using PET-MRI in Intensive Care Unit
In last decades, several advances in the neuro-intensive management have lead to decrease mortality in Intensive Care Units. A significant morbidity remains as patients survive after a traumatic coma with uncertain quality of…
- Trial name
- ETIC (NCT02798588)
- Testing
- PET-MRI
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Hospices Civils de Lyon
Aortic Stenosis, Heart Block
Conduction Disease After Transcatheter Aortic Valve Replacement
This is a prospective single center Cardiology department observational study. The study aim is to better understand the predictors of high grade conduction abnormalities associated with TAVR such that a more robust…
- Conditions
- Aortic Stenosis, Heart Block, Aortic Insufficiency
- Trial name
- NCT04489095
- Testing
- Electrophysiology Study
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Henry Ford Health System
Persistent Atrial Fibrillation
Endocardial Mapping With the CoreMap EP Mapping System
This is a global, multi-site, prospective, feasibility study.
- Trial name
- INvENI (NCT06529978)
- Testing
- CoreMap EP Mapping System Mapping, CoreMap EP Mapping System Map-Guided Ablation
- Where
- 4 sites in United States, Czechia
- Volunteers
- 245 people
- Sponsor
- CoreMap Inc.
Refractory Epilepsy, Neuromodulation
Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG
The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy.
- Trial name
- NCT07305311
- Testing
- SEEG recordings and SPES
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Crohn Disease, Functional Gastrointestinal Disorders
Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodes
The goal of this clinical trial is to compare the gastro-intestinal biopotentials recorded with a homemade device using surface electrodes placed on the abdomen in healthy volunteers, Crohn's disease patients without fibrosis…
- Conditions
- Crohn Disease, Functional Gastrointestinal Disorders, Healthy
- Trial name
- GRELE (NCT06197334)
- Testing
- Gastro-intestinal biopotentials recording
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Myofascial Trigger Points
A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points
To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for…
- Trial name
- NCT03082547
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Parkinson Disease
Combined Deep Brain Stimulation for Parkinson's Disease
Background: Deep brain stimulation (DBS) in the subthalamic nucleus (STN) is an approved treatment for Parkinson s disease. It stimulates a part of the brain that helps control symptoms like tremor, stiffness, and slow movements.
- Trial name
- NCT01485276
- Testing
- DBS Surgery
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hypertension
Impact of Catecholamine Spill-over on Outcome After RDN and EP Ablation
Despite a rapidly increasing number of renal denervation (RDN) procedures, only little is known regarding the patient or procedural characteristics influencing the outcome.
- Trial name
- RDN-Cath-1 (NCT01875809)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Witten/Herdecke
Premature Ejaculation
Research and Clinical Value of New Classification for Premature Ejaculation: Multi-Center Research
An observational study on the effect of new classification for premature ejaculation.
- Trial name
- NCT02572037
- Where
- 6 sites in China
- Volunteers
- 568 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Vagus Nerve Diseases, Epilepsy
Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Electroceuticals is a new field in which the goal is to treat a wide variety of medical diseases with electrical stimulation of autonomic nerves.
- Conditions
- Vagus Nerve Diseases, Epilepsy, Vagus Nerve Autonomic Disorder
- Trial name
- EITsVNS (NCT05664854)
- Testing
- Nerve cuff electrodes for spatially selective vagus nerve stimulation and electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College, London
In Vitro Fertilization, Estradiol
Impact of Supraphysiological Estradiol on ECG in IVF Patients
This prospective observational study aimed to evaluate the effects of supraphysiological estradiol (E2) levels, induced by gonadotropin therapy during IVF, on cardiac electrophysiological parameters.
- Conditions
- In Vitro Fertilization, Estradiol, Cardiac Electrophysiology, Electrocardiography (ECG)
- Trial name
- NCT07007416
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Konya City Hospital
Neurocardiogenic Syncope, Vasovagal Syncope
Cardioneuroablation for Neurocardiogenic Syncope
The purpose of this study is to evaluate the effectiveness of cardioneuroablation for the treatment of neurocardiogenic syncope (NCS), also known as "vaso-vagal" syncope.
- Trial name
- Ablate-NCS (NCT02009982)
- Testing
- Cardioneuroablation, Biosense Webster Navistar ThermoCool Diagnostic/Ablation Deflectable Tip Catheter
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- David B. De Lurgio
Major Depressive Disorder
Electrophysiologic Parameters and Biomarkers Predicting Treatment Response in Patients With Major Depressive Disorder
To explore electrophysiologic parameters and biomarkers predicting treatment response of patients with major depressive disorder To explore electrophysiologic parameters and biomarkers predicting suicide risk of patients with…
- Trial name
- NCT01997580
- Testing
- escitalopram
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Atrial Flutter
Cardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter
The purpose of this clinical study is to evaluate the and performance of the Imricor Medical Systems, Inc. (Imricor) MR Ablation Catheter when used with related accessories for the treatment of type I atrial flutter.
- Trial name
- NCT02699034
- Testing
- ablation for typical atrial flutter, Vision-MR ablation catheter
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- University of Leipzig
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lewy Body Disease
Dynamical Electrophysiology and Neuropathology in Lewy's Bodies Disease
Lewy body disease (LBD) is a neurodegenerative disorder that causes cognitive and behavioral problems. However, it is difficult to diagnose, and its pathophysiology is still not fully understood.
- Trial name
- DYNAPATH-LB (NCT07335692)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France