Clinical trials: Elevated Blood Sugar
Diabetes Mellitus, Impaired Glucose Tolerance
Skin Autofluorescence (AF) Decision Tree in Detecting Impaired Glucose Tolerance (IGT) or Diabetes Mellitus (DM)
Early detection of (pre)diabetes, including impaired glucose tolerance is currently deficient because the best accepted standard, an oral glucose tolerance test (oGTT), is not feasible in a setting of screening or broad…
- Trial name
- NCT01406665
- Where
- 2 sites in Netherlands
- Volunteers
- 218 people
- Sponsor
- University Medical Center Groningen
Obesity, Hypertension
A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients
The main purposes of this study are to find out if the study drug losartan (Cozaar) or placebo ("sugar pill") has an effect on insulin sensitivity (how your body responds to insulin) and to measure the effect of the study drug…
- Conditions
- Obesity, Hypertension, Hyperglycemia
- Trial name
- NCT00675987
- Testing
- losartan
- Where
- 9 sites in United States
- Volunteers
- 53 people
- Sponsor
- Brigham and Women's Hospital
Postprandial Hyperglycemia, Heart Rate Variability
Effect of Feet and Calf Heating on Glucose Tolerance
Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).
- Trial name
- NCT04232098
- Testing
- Heat to ankle, Heat to calf
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Hyperglycemia
Fat Based Enteral Nutrition for Blood Glucose Control in ICU
In this randomized, double-blind clinical trial, eligible hospitalized ICU patients with EN will be included. Patients will be divided into two groups.
- Trial name
- NCT02584907
- Testing
- High Fat Enteral Nutrition
- Where
- Iran
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Obesity, Pre-diabetes
The Effect of Time-Restricted Eating in Cardiometabolic Health
Time-restricted eating (TRE) is a dietary manipulation that involves restricting food intake to 6-12 h/day with no energy intake the rest of the day.
- Trial name
- NCT04484987
- Testing
- 9 hours daily eating window, 15 hours daily eating window
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Davis
Hyperglycemia, Leukemia
Intensive Glycemic Control on Infectious Morbidity In Patients With Acute Leukemia
RATIONALE: Controlling blood sugar levels may be effective in preventing infections in patients receiving chemotherapy for acute myeloid leukemia or acute lymphoblastic leukemia.
- Trial name
- NCT00943709
- Testing
- insulin glargine recombinant, therapeutic insulin
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Type 1 Diabetes
The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes
The purpose of this study is to see if reducing the dose of insulin before a meal and giving both pramlintide and insulin as dual wave infusions will lower the chance of low blood sugars after a meal.
- Trial name
- NCT00206297
- Testing
- Pramlintide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Diabetes Mellitus, Type 2
Benefits of Insulin Supplementation for Correction of Hyperglycemia in Patients With Type 2 Diabetes
The purpose of this study is to test whether using extra doses of aspart insulin to correct blood sugars before meals improves the care of patients with type 2 diabetes in the hospital who are already receiving the standard of…
- Trial name
- NCT02408120
- Testing
- Insulin glargine, Insulin aspart, Supplemental insulin aspart
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- Emory University
Obesity, Bariatric Surgery
Effects of Bariatric Surgery on Insulin
This study, conducted at the NIH Clinical Research Unit (CRU) at the Phoenix Indian Medical Center, will compare the effects of two methods of bariatric surgery, the adjustable BAND and Roux-en-Y gastric bypass, on insulin.
- Conditions
- Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss
- Trial name
- NCT00535600
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cystic Fibrosis-related Diabetes
EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis
Cystic Fibrosis Related Diabetes has been identified by the CF community as one of the top ten priorities for CF research. In CF clinical decline due to dysglycemia begins early, prior to diagnosis of diabetes and increases…
- Trial name
- NCT03650712
- Testing
- Oral glucose tolerance test, Continuous glucose monitoring, Dexa scan
- Where
- 4 sites in United States
- Volunteers
- 317 people
- Sponsor
- Katie Larson Ode
Hyperglycemia, Postprandial
Efficacy of Glucosanol™ in Reducing Post-prandial Glucose Levels in Overweight Subjects
Glucosanol had previously been proven to be effective in aiding weight loss and weight loss maintenance. Studies have also shown that Glucosanol (also known as Phaseolamin), was effective in aiding weight loss and also has…
- Trial name
- NCT02930681
- Testing
- Glucosanol 500mg
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Obesity, Dysglycemia
Metabolic Effects of Betaine Supplementation
Betaine is important in cellular metabolic pathways. Few epidemiologic studies link betaine levels to diabetes and cardiovascular disease. Small human studies suggest benefit for non-alcoholic liver disease.
- Trial name
- NCT01950039
- Testing
- Betaine
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Joslin Diabetes Center
Postprandial Hyperglycemia
Beneficial Effect of Xylose Consumption on Postprandial Hyperglycemia
The present study determined the effect of Xylose consumption on postprandial hyperglycemia in normal (n=25) and hyperglycemic subjects (n=50).
- Trial name
- NCT02654301
- Testing
- Test 1, Test 2, Test 3
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pre-diabetes, Impaired Glucose Tolerance
The Effect of Real Time Continuous Glucose Monitoring in Subjects With Pre-diabetes
This study will investigate whether real-time continuous glucose monitoring can be used as a tool for behavior change in people with pre-diabetes.
- Trial name
- CGM PreDM (NCT01741467)
- Testing
- RT-CGM
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Walter Reed National Military Medical Center
Type II Diabetes
Impact of the Rapid Normalization of Chronic Hyperglycemia and the Practice of Moderate Physical Activity on the "Receptor Activator of Nuclear Factor-kappa B Ligand / Osteoprotégérine (RANKL / OPG) System in Patients Living With Type II Diabetes
The rapid normalization of hyperglycemia can cause a neuropathy called Diabetes Treatment-Induced Neuropathy (NITD). This phenomenon induces the presence of hyper vascularization and inflammation in contact with the nerve ends.
- Trial name
- RANKL-GLYC (NCT04893135)
- Testing
- pratice physical activity
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Sud Francilien
Pre-diabetes
Supplementation of YMETA, on Gut Health, Immunity and Metabolism in Pre-diabetic Adult Population
Type 2 diabetes mellitus (T2DM) is a major non-communicable disease and one of the world's fastest growing health problems. According to a 2019 report, about 463 million adults worldwide currently have diabetes and future…
- Trial name
- YMETA (NCT05400525)
- Testing
- YMETA
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Roehampton
Type 1 Diabetes Mellitus
Model Predictive Control (MPC) Artificial Pancreas vs. Sensor Augmented Pump (SAP)/Predictive Low Glucose Suspend (PLGS) With Different Food Choices in the Outpatient Setting
The objective of this randomized crossover clinical trial is to 1) assess the efficacy and safety of an automated insulin delivery (AID) system using a Model Predictive Control (MPC) algorithm versus sensor augmented pump therapy…
- Trial name
- NCT03767790
- Testing
- iAPS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sansum Diabetes Research Institute
Hypertension, Hyperlipidemia
Cardiovascular Lifestyle Study: Effects and Expense of a Cardiovascular Risk Reduction Clinic in Primary Care
The purpose of this trial is to study the effects on risk reduction and expense of 3 approaches to the care of people with cardiovascular risk factors in a naturalistic primary care environment.
- Conditions
- Hypertension, Hyperlipidemia, Hyperglycemia, Cardiovascular Disease
- Trial name
- NCT00291824
- Testing
- Cardiovascular risk factors and willingness to change
- Where
- Canada
- Volunteers
- 670 people
- Sponsor
- Caroline Medical Group
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
Pancreatic Leak, Pancreatic Fistula
A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula
This is a single arm investigator-initiated study designed to test the feasibility and potential efficacy of preoperative lanreotide to reduce the risk of postoperative abscess or pancreatic leak and fistula.
- Conditions
- Pancreatic Leak, Pancreatic Fistula, Pancreaticoduodenal; Fistula, Pancreatectomy; Hyperglycemia
- Trial name
- NCT03174353
- Testing
- Lanreotide Prefilled Syringe
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Washington
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