Clinical trials: Elevated Blood Sugar
Type 2 Diabetes Mellitus (T2DM), Obesity and Type 2 Diabetes
Impact of Fenugreek Supplementation on Obesity and Hyperglycemia Among Diabetic Adults in Saudi Arabia
The goal of this clinical trial is to learn if Fenugreek seed powder helps lower body weight and blood sugar in adults with type 2 diabetes who are overweight or obese.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity and Type 2 Diabetes, Hyperglycemia
- Trial name
- NCT07038577
- Testing
- Fenugreek Seed Powder
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- University of Hail
Beta-Thalassemia, Insulin Resistance
Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to Insulin
It is known that postprandial hyperglycemia increases the cardiometabolic risk in both diabetic and non-diabetic patients. Moreover, there is insufficient data on the effectiveness of exercise on preventing Type II diabetes…
- Conditions
- Beta-Thalassemia, Insulin Resistance, PreDiabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT03889977
- Testing
- Resistance exercise
- Where
- Greece
- Volunteers
- 6 people
- Sponsor
- University of Thessaly
Type 1 Diabetes
Effect of Type 1 Diabetes on Sleep Fragmentation
The main objective of this study is the objective evaluation of disease related sleep fragmentation in subjects with type 1 diabetes.
- Trial name
- DIAPASOM5 (NCT04601519)
- Testing
- Cross-sectional observational study
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Grenoble
Peritonitis, Surgical Site Infection
Continuous Glucose Monitoring for Emergency Laparotomy
CLUE trial aims to determine the feasibility and predictive value for surgical site infection (SSI) of continuous glucose monitoring (CGM) in emergency laparotomy patients with diffuse peritonitis.
- Conditions
- Peritonitis, Surgical Site Infection, Infections, Hyperglycemia
- Trial name
- CLUE (NCT05641792)
- Testing
- CGM (Dexcom G6)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Diabetic Macular Edema, Visual Impairment
Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant
This study aims to investigate the association between serum biomarkers and clinical response to anti-VEGF or dexamethasone implant by assessing OCT-biomarkers in patients with diabetic macular edema, DME, and to compare these…
- Conditions
- Diabetic Macular Edema, Visual Impairment, Diabetes Mellitus, Hyperglycaemia (Diabetic)
- Trial name
- BiomarkerOCT (NCT06984822)
- Testing
- Anti-VEGF treatment, Dexamethasone implant, Treatment with intravitreal anti-VEGF OR Dexamethasone implant
- Where
- 2 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Vastra Gotaland Region
Precursor Cell Lymphoblastic Leukemia-Lymphoma, Drug-Induced Diabetes Mellitus
Glucose Intolerance and Diabetes Related to Treatment With Steroids and PEG- Asparaginase in Children and Adolescents With ALL and Lymphoma
The overall survival of acute lymphoblastic leukemia (ALL) and lymphoma in children and adolescents is above 90%. The survival rate has increased significantly during the last decades as a consequence of more intensive…
- Conditions
- Precursor Cell Lymphoblastic Leukemia-Lymphoma, Drug-Induced Diabetes Mellitus, Impaired Glucose Tolerance, Lymphoma
- Trial name
- NCT05873322
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Cerebrovascular Accident, Diabetes
Impact of Diabetes and Glucose Control During Rehabilitation After Stroke
To assess whether patients with diabetes have less clinical improvement during inpatient rehabilitation than those without diabetes and whether hyperglycaemia during rehabilitation is an adverse prognostic indicator.
- Conditions
- Cerebrovascular Accident, Diabetes, Hyperglycemia
- Trial name
- NCT00241956
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Melbourne Health
COPD, Hyperglycemia
Phase II Study of Safety and Feasibility of Intensive Blood Glucose Control With Insulin on Acute Medical Wards
Patients with chronic obstructive pulmonary disease (COPD) are commonly admitted to hospital with exacerbations of their lung disease.
- Trial name
- IPS2008 (NCT00764556)
- Testing
- Insulin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- St George's, University of London
Genetic Predisposition to Disease, Hyperglycemia
TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure
This study evaluates the link between genetic polymorphisms as r7903146, rs12255372 of TCF7L2 gene and the risk of developing hyperglycemia during Intensive care unit stay
- Conditions
- Genetic Predisposition to Disease, Hyperglycemia, Intensive Care Unit Syndrome, Multiple Organ Failure
- Trial name
- READIAB-G4 (NCT03055169)
- Testing
- genetic analysis, blood and stools samples
- Where
- 5 sites in France
- Volunteers
- 994 people
- Sponsor
- University Hospital, Lille
Small Intestinal Bacterial Overgrowth, Lactose Intolerance
Clinical Utility of Breath Tests in GI
Bloating, gas, pain and diarrhea are common complaints. Routine investigations are negative; these patients are labeled as IBS. In these patients, whether testing for carbohydrate malabsorption or small intestinal bacterial…
- Conditions
- Small Intestinal Bacterial Overgrowth, Lactose Intolerance, Fructose Intolerance, Glucose Intolerance
- Trial name
- NCT03261856
- Where
- United States
- Volunteers
- 1,080 people
- Sponsor
- Augusta University
Diabetes Mellitus Type 2, Hyperglycemia
Efficacy of GLP-1 Infusion in Comparison to an Insulin Infusion Protocol to Reach Normoglycemia Type 2 Diabetic Patients
The aim of the investigators study was to compare for the first time efficacy and safety of intravenously administered GLP-1 with an established intravenous insulin regimen in hyperglycaemic type 2 diabetic patients.
- Trial name
- NCT00859079
- Testing
- GLP-1, Human regular insulin intravenously
- Where
- Austria
- Volunteers
- 8 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Obesity
Investigating Muscle Failure in Diabetic Myopathy
The goal of this observational study is to assess if diabetes and obesity are independently related to functional and structural muscle deficits, and how muscular deficits relate to metabolic properties of diabetes and obesity.
- Conditions
- Diabetes Mellitus, Obesity, Chronic Hyperglycaemia, Weight Loss
- Trial name
- NCT05685927
- Testing
- 6-months of medically assisted glycemic improvement, Bariatric surgery
- Where
- Denmark
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Prediabetes, Impaired Fasting Glucose
Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes
Pre diabetes (PD) is a term that refers to alterations in glucose homeostasis, including impaired fasting glucose (IFG), Imparied glucose tolerance (IGT) or both, involving a higher risk to develop type 2 diabetes mellitus (T2DM)…
- Conditions
- Prediabetes, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT03029390
- Testing
- Berberine, Metformin
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- University of Guadalajara
Diabetes Mellitus, Type 2, Pre-diabetes
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans
The rationale for the proposed research is that elucidating changes in localized diacylglycerol (DAG) and sphingolipid species that predict insulin sensitivity will reveal specific localized lipids to target in therapeutics for…
- Conditions
- Diabetes Mellitus, Type 2, Pre-diabetes, Obesity
- Trial name
- NCT03077360
- Testing
- Lifestyle
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sickle Cell Disease, Obesity, Childhood
Obesity in Pediatric Sickle Cell Disease: A New Phenomenon
The objective of this project is to determine the prevalence of hypertension, hyperlipidemia and hyperglycemia in the pediatric population with sickle cell disease who are obese in Mississippi compared to those pediatric patients…
- Conditions
- Sickle Cell Disease, Obesity, Childhood, Hypertension, Hyperlipidemia in Children
- Trial name
- NCT04676113
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Mississippi Medical Center
Type2 Diabetes
Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes
This is an initial validation study of the Personal Nutrition Project (PNP) algorithm in a North American population with recently diagnosed Type 2 Diabetes (T2D).
- Trial name
- NCT03053518
- Testing
- Abbott Freestyle Libre Pro, LifeStyle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Hyperglycemia, Coronary Heart Disease
Paleolithic Diet in the Treatment of Glucose Intolerance
The purpose of this study is to determine whether a paleolithic diet improves glucose tolerance and insulin sensitivity in people with coronary heart disease and impaired glucose tolerance.
- Trial name
- NCT00419497
- Testing
- Paleolithic diet vs Mediterranean diet
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Lund University Hospital
Dyslipidemia, Impaired Glucose Tolerance
Dietary Modulation of Hepatic Lipase (LIPC) -514 C/T Variant Associations With Lipids and Glucose
The investigators evaluated dietary modulation of LIPC rs1800588 (-514 C/T) for lipids and glucose using a randomized cross-over design comparing a high-fat Western diet and a low-fat traditional Hispanic diet in Caribbean…
- Trial name
- NCT02938091
- Testing
- High-fat diet, Low-fat diet
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cystic Fibrosis Related Diabetes, Hyperglycaemia
Investigating the Relationship Between Glycemia and Sleep in Adults With Cystic Fibrosis-Related Diabetes
The goal of this at-home, remote study is to understand the relationship between blood sugars and sleep in adults living with Cystic Fibrosis Related Diabetes (CFRD).
- Conditions
- Cystic Fibrosis Related Diabetes, Hyperglycaemia, Insomnia, Cardiometabolic Diseases
- Trial name
- NCT06700889
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Type 1 Diabetes, Hyperglycemia Stress
Competition Induced Hyperglycemia in Athletes With Type 1 Diabetes
Design and methods 12 athletes with T1D and 12 healthy athletes are included in a prospective experimental randomized, cross-over study.
- Trial name
- EXCITE-1 (NCT05561517)
- Testing
- 5 K running
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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