Clinical trials: Elevated Blood Sugar
Type 2 Diabetes
Substitution of First Phase Insulin Response in Patient With Type 2 Diabetes.
The purpose of the project is to shown whether a little dose of a short acting insulin analogue given 3 time daily before the meals compared with placebo could normalise the increase in blood glucose after teh meals in diet…
- Trial name
- NCT00254085
- Testing
- Insulin Aspart
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Hyperglycemia, Hyperglucagonemia
Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)
The incretin hormone glucagon-like peptide-1 (GLP-1) has known insulinotrophic and glucagonostatic properties. However, inpatients with type 2 diabetes mellitus (T2DM)it is shown, that the beta cell sensitivity towards GLP-1 is…
- Conditions
- Hyperglycemia, Hyperglucagonemia, Glucose Intolerance
- Trial name
- NCT00862589
- Testing
- GLP-1 infusion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Diabetes Mellitus, Pre Diabetes
Full Plate Living Nutrition Education Program
The purpose of the research is to evaluate the acceptability and feasibility of implementing a 8-session nutritional education program in a general internal medicine clinic.
- Conditions
- Diabetes Mellitus, Pre Diabetes, Obesity
- Trial name
- NCT07271940
- Testing
- Full Plate Living Nutrition Education Program
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Wisconsin, Madison
Obesity, Heart Failure
The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure
The aim of this trial is to assess the effect of Empagliflozin on lipid and glucose metabolism as well as volume homeostasis and renal function in elderly and obese patients with increased risk of developing heart failure.
- Trial name
- NCT05042973
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Denmark
- Volunteers
- 165 people
- Sponsor
- Jacob Moller
Elevated Blood Glucose
Whole-Food Magnesium for Mental and Cardiometabolic Health
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of daily supplementation with E-Z Mg™, a commercially available whole-food-based magnesium supplement, on sleep, mood, fatigue, and…
- Trial name
- NCT07865351
- Testing
- Low-Dose Whole-Food-Based Magnesium Supplement, Moderate-Dose Whole-Food-Based Magnesium Supplement
- Volunteers
- 45 people
- Sponsor
- George Mason University
Hypertension, Cardiovascular Disease
Regional Innovation in Chronic Disease and Elderly Care
This project aims to develop a community-based health promotion intervention model for populations at potential risk of metabolic syndrome.
- Conditions
- Hypertension, Cardiovascular Disease, Hyperlipidemia, Hyperglycemia
- Trial name
- NCT07578090
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Fu Jen Catholic University
Diabetes
Management of Hyperglycemia in the ER: A Randomized Clinical Trial of a Subcutaneous Insulin Aspart Protocol Coupled With Rapid Initiation of Basal Bolus Insulin Prior to Hospital Admission Versus Usual Care
In the Emergency Department (ED), diabetes is commonly encountered as a secondary diagnosis and many patients with uncontrolled diabetes are admitted to the hospital after initial evaluation in the ED.
- Trial name
- NOVO ER (NCT00663624)
- Testing
- aspart insulin, Usual care as prescribed by the ED physicians.
- Sponsor
- Emory University
Pregnancy Complications, Diabetes Mellitus
Correlation of CGM Metrics With OGTT and Pregnancy Outcomes in Pregnant Women With or Without a High Risk for GDM
the aim of the study is to obtain CGM data concomitant with OGTT and to determine what CGM metrics obtained in pregnant women with and without a high risk of GDM correlate best with the diagnostic OGTT (obtained via the 2-step…
- Conditions
- Pregnancy Complications, Diabetes Mellitus, Hyperglycemic Disorder
- Trial name
- NCT05537480
- Testing
- Continuous glucose monitoring device
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pre-diabetes
A Smartphone-based Intervention for Diabetes Prevention in Overweight Chinese Adults With Pre-diabetes
Type 2 diabetes (T2DM) is a serious chronic condition and one of the world's fastest growing health problems. The onset of T2DM is gradual, with most individuals progressing through a state of pre-diabetes, which provides an…
- Trial name
- NCT04875780
- Testing
- Digital diabetes prevention app intervention, Digital weight loss tracking app intervention, Wait-list control (usual care)
- Where
- Hong Kong
- Volunteers
- 282 people
- Sponsor
- The University of Hong Kong
High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar
Health Effects of Grain Foods in Adults
This study will assess the effects of eating whole grain foods versus refined grain foods with different amounts of added sugar.
- Conditions
- High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar, Low Whole Grain and Low Sugar, Low Whole Grain and High Sugar
- Trial name
- NCT06339879
- Testing
- High Whole Grain, Low Sugar, Low Whole Grain, Low Sugar, High Whole Grain, High Sugar
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Pre-diabetic
Personalized Glucose Optimization Through Nutritional Intervention
Maintaining well-controlled blood glucose concentrations is essential in the prevention of chronic cardiometabolic diseases. The blood glucose response to dietary and/or lifestyle patterns may vary between individuals.
- Conditions
- Obesity, Pre-diabetic, Type 2 Diabetes Mellitus
- Trial name
- PERSON (NCT03708419)
- Testing
- Optimal diet, Suboptimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pre-Diabetes
Full-fat Yogurt and Glucose Tolerance
This study determines if substituting full-fat yogurt (i.e., whole, 3.25% fat) for non-fat yogurt in the diet can reduce the risk of type 2 diabetes and inflammation in association with changes in the composition of the…
- Trial name
- NCT03577119
- Testing
- Full-fat yogurt, Non-fat yogurt
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Impaired Glucose Tolerance
Sucralose, Stevia, Gut Microbiome and Glucose Metabolism
This study will determine the influence of two non-caloric sweeteners on glucose metabolism via the gut microbiome in adult men and women.
- Trial name
- NCT02800707
- Testing
- Sucralose, Stevia
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Diabetes
Effect of Yellow Pea Protein and Fibre Added to a High-carb Meal on Glycemic Response and Food Intake
The investigators hypothesized that consuming isolated yellow pea fibre or protein, alone to together, as part of a high-carbohydrate pasta meal, would reduce the blood glucose response to the meal compared to a meal without…
- Trial name
- NCT02015429
- Testing
- Pasta meal with added fractions or control with no fractions
- Where
- 2 sites in Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Impaired Glucose Tolerance, Fetal Macrosomia
Treatment of Impaired Glucose Tolerance in Pregnancy
The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia…
- Trial name
- TIP (NCT00625781)
- Testing
- Insulin aspart and Insulin human (isophane)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Type 1 Diabetes, Type 2 Diabetes
Closed Loop Glucose Control in a Simulated ICU Setting
This is a proof of concept safety study of a rule-based closed loop glucose control system designed for use in the intensive care unit setting.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Stress Induced Hyperglycemia
- Trial name
- NCT07646067
- Testing
- FUSION closed loop glucose control system
- Volunteers
- 6 people
- Sponsor
- Ideal Medical Technologies
Diabetes Mellitus, Critical Illness
Degludec Insulin Use in Critically Ill Patients
Background: Dysglycemia in critically ill patients is common, where 40% to 54% of patients were found to be hyperglycemic on intensive care unit admission.
- Conditions
- Diabetes Mellitus, Critical Illness, Hyperglycemia
- Trial name
- NCT06056167
- Testing
- Degludec insulin
- Where
- Saudi Arabia
- Volunteers
- 155 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Cystic Fibrosis
Sitagliptin in Cystic Fibrosis-Related Diabetes
The purpose of this study is to determine whether the dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin is effective in the treatment of cystic fibrosis-related diabetes (CFRD).
- Trial name
- NCT01257464
- Testing
- Sitagliptin
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Postprandial Glycemic Response, Postprandial Hyperglycemia
Short, Simple, Exercise to Improve Circadian Dependent Postprandial Glycemic Responses
The goal of this clinical trial is to test whether one minute of stair stepping at a comfortable pace can reduce blood sugar after meals.
- Conditions
- Postprandial Glycemic Response, Postprandial Hyperglycemia, Postprandial Insulin
- Trial name
- NCT05783752
- Testing
- Stair Stepping, No exercise control
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Hyperglycemia, Hematopoietic Stem Cell Transplantation
Glucose Control In Hematopoetic Stem Cell Transplant
To determine whether intensive glucose control results in improved mortality and reduced hospital stay length by performing a randomized trial of intensive glucose management (blood glucose goal 110 mg/dl) using continuous IV…
- Trial name
- NCT00582036
- Testing
- Regular Insulin, Deployment of the MiniMed Paradigm monitoring device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.