Clinical trials: Elevated Blood Sugar
Obesity, Hyperlipidemia
Lepticore in Metabolic Syndrome and Weight Loss
Metabolic syndrome is directly related to obesity. This study investigated the use of a plant based formulation to improve on the condition of people with metabolic syndrome.
- Conditions
- Obesity, Hyperlipidemia, Hyperglycemia
- Trial name
- NCT01046968
- Testing
- Lepticore
- Where
- Cameroon
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Yaounde 1
Ischaemic Stroke, Cognitive Impairment, Mild
Cognitive Care Bundle for Ischaemic Stroke : A Pilot Randomised Controlled Trial
The goal of this clinical trial is to learn if a set of treatments, called a "cognitive care bundle," can help preserve cognitive ability in people who have had a stroke.
- Trial name
- COGIS (NCT07610291)
- Testing
- Cognitive care bundle, Standard Medical Care (SMC)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- National University of Malaysia
Diabetes in Pregnancy
Single Non-fasting OGTT Versus Fasting OGTT for Screening of Hyperglycaemia in Pregnancy (HIP)
With the increasing prevalence of diabetes in pregnancy it is necessary to design a simple, sensitive, cost effective method for screening of hyperglycaemia in pregnancy specially in resource constrained settings.
- Trial name
- NCT04129190
- Testing
- Glucose
- Where
- Pakistan
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Isra University
Pre Diabetes, Vascular Stiffness
Dietary Exchanges With Avocado and Mango in Pre-diabetes
The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals…
- Conditions
- Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change
- Trial name
- AVMa (NCT05353790)
- Testing
- Meals + snacks: control, Meals + snacks: Avocado mango
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Complication of Transplanted Organ, Nos
Glucose/Insulin Clamp on Solid Organ Transplant (Liver, Kidney, Pancreas and Heart) on Cadaveric Donors
Our objective in this study will be to determine if implementing the glucose/insulin clamp (GICT) on cadaveric organ donors can: Prevent hyperglycaemia Drop in the inflammatory cytokine response after brain death after a minimum…
- Trial name
- NCT01304290
- Testing
- Hyperinsulinemic/normoglycemic clamp
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Glucose Intolerance
The Effect of Momordica Charantia Supplementation on Blood Glucose Levels
The study is a randomized, cross-over, double blind, controlled trial in which study participants will receive two 4-week interventions with a washout period of 4 weeks between interventions.
- Trial name
- Bitter-sweet (NCT04090788)
- Testing
- dried bitter-gourd supplements, dried cucumber supplements
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Wageningen University and Research
Stress Hyperglycaemia
Closed Loop Glucose Control in Intensive Care Unit
The purpose of this study is to assess the efficacy, safety and feasibility of a computer-based control algorithm to control glucose levels in adults in intensive care unit, in comparison to standard care.
- Trial name
- CLASSIC (NCT01440842)
- Testing
- Closed-loop insulin delivery, Standard IV insulin infusion sliding scale
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Cambridge
Impaired Glucose Tolerance, Type 2 Diabetes
Impact of 3-year Lifestyle Intervention on Postprandial Glucose Metabolism: the SLIM Study
To evaluate the effect of a 3-year diet- and exercise lifestyle intervention, based on general public health recommendations, on glucose tolerance, insulin resistance and metabolic cardiovascular risk factors in Dutch subjects…
- Trial name
- NCT00381186
- Testing
- diet- and exercise intervention
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes
Application and Effectiveness Analysis of Internet-based Diabetes Prevention Program
This study was conducted to test the possibility of preventing or delaying the development of type 2 diabetes in individuals with impaired glucose tolerance and elevated fasting plasma glucose concentrations by internet-based…
- Trial name
- NCT01085682
- Testing
- Lifestyle counseling, Standard care
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Diabetes Mellitus Type 2, Hospitalization
Effect of the Use of Continuous Glucose Monitoring Versus Standard Glycemic Control in Hospitalized Patients with Type 2 Diabetes.
Type 2 diabetes (T2D) is a common pathology in hospitalized patients and is associated with multiple comorbidities. Moreover, it is widely known that glycemic excursions increase hospital stay, infections, morbidity and…
- Trial name
- NCT06607224
- Testing
- Experimental (Decision making guided by CGM)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Feeding Patterns, Sleep
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic…
- Conditions
- Feeding Patterns, Sleep, Glucose Intolerance
- Trial name
- NCT04737200
- Testing
- Time-of-day of enteral nutrition provision (daytime first), Time-of-day of enteral nutrition provision (nighttime first)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Prediabetic State, Impaired Fasting Glucose
Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients
Pre-diabetes is a state characterized by subclinical impairment in glycemic variables that is intermediate between normal glucose tolerance (NGT) and diabetes.
- Conditions
- Prediabetic State, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT05914857
- Testing
- Dapagliflozin 10mg Tab, lifestyle interventions
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yangjin
PreDiabetes, Appetitive Behavior
Prediabetes, Exercise, and Appetite Regulation
The purpose of the study is to learn about how type of exercise influences measures of appetite regulation.
- Trial name
- PEAR (NCT04910763)
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus
Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes
Steroid injections used to treat painful joints can temporarily increase glucose levels in people with type 2 diabetes. This study will test whether a short course of pre-emptive neutral protamine Hagedorn, NPH, insulin can…
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus, Osteoarthritis, Knee
- Trial name
- PREVENT-SIH (NCT07757464)
- Testing
- Insulin Isophane Human, NPH, Pre-emptive Algorithm, Triamcinolone Acetonide Knee Injection
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- Shifa International Hospital
Pre-diabetes
Effects of a Dietary Supplement Containing L-Arabinose and Trivalent Patented Food-source of Chromium on Blood Glucose and Insulin
This study was designed to examine changes in capillary blood glucose and venous insulin levels after a 70 gram oral sucrose challenge with and without simultaneous consumption of a dietary supplement containing L-Arabinose and a…
- Trial name
- L-Arabinose (NCT01107431)
- Testing
- L-Arabinose and Chromium, Sucrose without dietary Supplement
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Diabetes Mellitus, Type 2, Hypoglycemia
FreeStyle Libre 2 Discharge Trial
The goal of this clinical trial is to learn about the benefits of using aa Continuous Glucose Monitoring (CGM) system in patients with diabetes following discharge from the hospital.
- Trial name
- NCT05822232
- Testing
- FreeStyle Libre 2 CGM, FreeStyle Libre Pro blinded CGM, FreeStyle Precision Neo blood glucose meter
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Palo Alto Medical Foundation
Critical Illness
Individualized Blood Glucose Control in ICU. The CONTROLING Study. A Double Blinded Multicentric Randomized Study.
During the last 2 decades, the management of hyperglycemia in critically ill patients has become one of the most discussed topics in the intensive-care field.
- Trial name
- CONTROLING (NCT02244073)
- Testing
- Human insulin - Insulin administration to control blood glucose level.
- Where
- 12 sites in France
- Volunteers
- 2,069 people
- Sponsor
- Hospices Civils de Lyon
Hyperglycemia
The Effect of n-3 Fatty Acids and Fish on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Metabolism
The aim of the project is to examine whether the sources of n-3 fatty acids and fish itself differ in their effects on glucose metabolism, lipid metabolism, blood pressure, and serum inflammatory markers.
- Trial name
- NCT01768429
- Testing
- Fatty fish, Lean Fish, Alpha-linolenic acid
- Where
- Finland
- Volunteers
- 79 people
- Sponsor
- University of Eastern Finland
Diabetes Mellitus
Effect of Anakinra on Insulin Sensitivity in Type 1 Diabetes Mellitus
The purpose of this study is to test whether anakinra is able to reduce insulin resistance. This will be tested in overweighted type I diabetes mellitus patients, which have no residual beta-cell function.
- Trial name
- NCT01285245
- Testing
- kineret
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Radboud University Medical Center
Pancreatic Cancer, Pancreatic Carcinoma
A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer
The purpose of this study is to find out how effective and safe glipizide is for lowering blood sugar in people with pancreatic cancer.
- Conditions
- Pancreatic Cancer, Pancreatic Carcinoma, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Metastatic
- Trial name
- NCT06168812
- Testing
- Glipizide
- Where
- 7 sites in United States
- Volunteers
- 29 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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