Clinical trials: Elevated Blood Sugar
Diabetes Mellitus
Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care
The purpose of the study is to determine if the administration of small doses of Acarbose can prevent or delay the appearance of Type 2 Diabetes Mellitus in a population of subjects with prediabetes.
- Trial name
- NCT01010100
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- 23 sites in Spain
- Volunteers
- 204 people
- Sponsor
- Bayer
Hyperandrogenism
Effects of Androgen Administration on Inflammation in Normal Women
The hypothesis of this study is that DHEA administration to increase male hormone in healthy normal-weight young women to levels present in women with Polycystic Ovary Syndrome will cause an inflammatory response in white blood…
- Trial name
- NCT01753037
- Testing
- Dehydroepiandrosterone (DHEA)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus
The Effects of High and Low Blood Glucose Values on the Brain in Children With Type 1 Diabetes Mellitus
Simplified Brochure Neuropsychological Testing/Assessment is like games for the child. They are asked to complete the sequence, identify pictures, explain what is happening, etc. There is no personality testing involved.
- Trial name
- NCT01690481
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes, Pre-diabetes
Effect of Oral L-arginine 3.32 g a Day on Oxidative Stress Influencing Beta Cell Function and Insulin Resistance.
The objective of this clinical trial is to explore whether L-arginine supplementation with 3.32g/day may enhance antioxidant defenses in overweight and obese patients with pre-diabetes and metabolic syndrome, possibly providing…
- Conditions
- Diabetes, Pre-diabetes, Metabolic Syndrome
- Trial name
- L-BIOARG (NCT06686069)
- Testing
- bioarginina zero
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federico II University
Impaired Glucose Tolerance
Resveratrol-Leucine Metabolite Synergy in Pre-diabetes
The study will evaluate the effects of resveratrol/leucine and resveratrol/HMB for their ability to control glucose levels in persons without diabetes but with impaired fasting glucose.
- Trial name
- NCT01593605
- Testing
- Resveratrol, resveratrol /HMB
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University
Insulin Resistance, Insulin Sensitivity
Fructose: Substrate, Stimulus, or Both?
This objective of this study is to use sensitive methodology under controlled conditions to investigate the mechanisms by which fructose consumption contributes to excess fatty acid synthesis and elevations in blood glucose…
- Conditions
- Insulin Resistance, Insulin Sensitivity, Pre Diabetes
- Trial name
- NCT04168372
- Testing
- High fructose, fructose labeled meal, High fructose, pyruvate labeled meal, Low fructose, fructose labeled meal
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Touro University, California
Diabetes Mellitus, Pre-diabetes
Tongue Fur and Metabolites in Diabetes Mellitus
This study is a prospective cross-sectional study. The investigators enroll participants form the department of endocrinology and of metabolism, China Medical University Hospital.
- Trial name
- NCT04909632
- Testing
- Liquid chromatography-mass spectrometry (LC-MS) analysis
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Hyperglycemia, Diabetes
An Open-randomized, Balanced, Crossover Bioequivalence Study to Compare One MR Tablet of 60 mg Gliclazide and Two MR Tablets of 30 mg Gliclazide in Healthy Subjects
The 2 × 2 crossover designed study is to evaluate the bioequivalence of two different MR tablets of gliclazide after single oral administration at the same doses to healthy subjects.
- Trial name
- NCT01195532
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Hyperglycemia
Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit
Insulin preparation -random assignment to regular insulin lin or lispro insulin as first treatment- was administered at constant infusion rate (0.04 units/Kg/h) in patients presenting blood glucose concentration ≥180 mg/dl and…
- Trial name
- NCT02165566
- Testing
- Regular-insulin, Lispro-insulin
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- University of Roma La Sapienza
Impaired Glucose Tolerance
Preliminary Safety and Efficacy Study of Extracellular Vesicle Infusion in the Intervention of Age-related Phenotypes With Impaired Glucose Tolerance.
The objective of this exploratory study was to evaluate the initial safety of human mesenchymal stem cell-derived extracellular vesicle infusion in an age-related phenotype with impaired glucose tolerance
- Trial name
- NCT06495437
- Testing
- Intravenous infusion of extracellular vesicle preparation derived from Wharton's jelly mesenchymal stem cells.
- Volunteers
- 20 people
- Sponsor
- BEAUTECH
HIV Infections, Pregnancy
Problems Associated With the Use of Anti-HIV Drugs in HIV-Infected Pregnant Women
The purpose of this study is to find out if HIV-infected pregnant women who take protease inhibitors (PIs) are more likely to have blood sugar problems than those who do not take PIs.
- Trial name
- NCT00017797
- Where
- 40 sites in United States, Puerto Rico
- Volunteers
- 160 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Glucose Intolerance, Glucose Metabolism Disorders
Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response
Strategies to control chronic postprandial hyperglycaemia by optimizing the functionality of foods would strengthen efforts to reduce the risk of developing T2D in the general population.
- Trial name
- NCT04004182
- Testing
- Fruit bar with addition of polyphenols
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Diabetes, Hyperglycemia
Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events
The purpose of this study is to determine whether an array of biosensors can noninvasively identify hyperglycemic or hypoglycemic events in persons diagnosed with diabetes through noninvasive detection of volatile organic…
- Conditions
- Diabetes, Hyperglycemia, Hypoglycemia
- Trial name
- NCT06893341
- Testing
- The Sensing Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Diabetes Mellitus
Insulin by Jet-injection for Hyperglycemia in Diabetes
The purpose of this study is to compare the pharmacokinetic and pharmacodynamic profile of the rapid-acting insulin analogue aspart (Novorapid®) injected subcutaneously by jet-injection to that of the same insulin injected with a…
- Trial name
- NCT01947556
- Testing
- insulin aspart
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Nijmegen
Critical Illness, Hyperglycemia
Multicentre LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness (LOGIC-2)
Most critically ill patients are confronted with hyperglycaemia, which is associated with an increased mortality and morbidity risk.
- Conditions
- Critical Illness, Hyperglycemia, Hypoglycemia
- Trial name
- LOGIC-2 (NCT02056353)
- Testing
- LOGIC-Insulin algorithm, Paper protocol
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 1,550 people
- Sponsor
- KU Leuven
Diabetes Mellitus, Type 2, Prediabetes
RCT of the Naturopathic Anti-Inflammatory Diet
The purpose of this study is to determine if the naturopathic Anti-Inflammatory Diet results in reduced inflammation and a better response by the immune system when compared to a standard diabetic diet based on the current…
- Trial name
- NCT00334919
- Testing
- Diet (Anti-Inflammatory or standard diabetic diet)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National University of Natural Medicine
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
GDM, Insulin Resistance
In Vitro Fertilization Impact on Metabolic Parameters
A quantitative prospective cohort study will be conducted, where blood samples will be collected at different timings during the IVF protocol, to assess the impact of fertility medications on metabolic parameters of patients…
- Conditions
- GDM, Insulin Resistance, Glucose Intolerance, PCOS
- Trial name
- IVF (NCT03426228)
- Testing
- HbA1C
- Where
- United Arab Emirates
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Ovary Cancer
The Effect of Glucose Level and Diabetes Mellitus on Ctrough of Olaparib
Monitored therapy of olaparib concentrations in the blood of diabetic population probably will assess the need for individual dosing of the drug.
- Trial name
- NCT05081765
- Testing
- Lynparza® (AstraZeneca Pharma Poland Sp. z o.o.), Lynparza
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Poznan University of Medical Sciences
Type 2 Diabetes Mellitus
The Effects of Pilates on Functional Capacity and Blood Glucose Levels in Adults With Diabetes Type 2
The aim of this study is to investigate the effects of the Pilates training on Functional Capacity among adults with type 2 diabetes The aim of this study is to investigate the effects of the Pilates training on blood glucose…
- Trial name
- NCT05261776
- Testing
- pilates exercise, brisk walk
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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