Clinical trials: Elevated Fibroblast Growth Factor-23
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Kidney Disease Requiring Chronic Dialysis, Hyperphosphatemia
Low-Phosphate Diet and Fibroblast Growth Factor-23 Level
The aims of the study are to evaluate the effect of low-phosphate diet on FGF23 level and to determine the optimal amount of dietary phosphate restriction in hemodialysis patients.
- Conditions
- Chronic Kidney Disease Requiring Chronic Dialysis, Hyperphosphatemia, Dietary Intervention, Elevated Fibroblast Growth Factor-23
- Trial name
- NCT03367338
- Testing
- Low-phosphate diet
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Wan-Chuan Tsai
Obstructive Sleep Apnea, Cardiovascular Diseases
Obstructive Sleep Apnoea and Cardiac Arrhythmias
This study is a prevelance trial looking at how sleep apnoea affects the heart especially heart rhythms. Previous research shows that patients suffering from sleep apnoea are much more likely to get heart disease and abnormal…
- Conditions
- Obstructive Sleep Apnea, Cardiovascular Diseases, Arrhythmia, Atrial Fibrillation New Onset
- Trial name
- OSCA (NCT03866148)
- Testing
- Reveal LINQ
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust