Clinical trials: Embryo
Infertility
Edessy ICSI Outcome Embryo Score (EIOS) Efficacy
Purpose of this study is to detect outcome of intracytoplasmic sperm injection (ICSI) according to EIOS
- Trial name
- NCT02082288
- Testing
- Edessy ICSI Outcome Embryo Score
- Where
- Egypt
- Volunteers
- 243 people
- Sponsor
- Al-Azhar University
IVF
Immediate Versus Postponed Freeze-all Embryo Transfer in Hyperresponders
This is a multicenter, randomised controlled trial. The investigators plan to randomise 836 participants to the immediate FET or the postponed FET from the day of oocyte retrieval to the last day of that menstrual cycle in a 1:1…
- Trial name
- NCT05483270
- Testing
- the timing of embryo transfer in freeze-all cycles
- Where
- China
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome
Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos Patients
The purpose of this study is to determine whether simvastatin is effective in the improvement of IVF-ICSI outcome in Pcos patients.
- Trial name
- NCT00575601
- Testing
- SIMVASTATIN
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tehran University of Medical Sciences
Pre-Eclampsia, Frozen Embryo Transfer
Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer
Identifying modifiable factors that contribute to preeclampsia risk associated with assisted reproduction can improve maternal health.
- Trial name
- PREECLAM-2019 (NCT04092829)
- Testing
- FROZEN EMBRYO TRANSFER IN SUBSTITUTED CYCLE
- Where
- Spain
- Volunteers
- 591 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Amyotrophic Lateral Sclerosis
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)
GM604 is an endogenous human embryonic stage neural regulatory and signaling peptide that controls the development, monitoring and correction of the human nervous system.
- Trial name
- GALS (NCT01854294)
- Testing
- GM604
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Genervon Biopharmaceuticals, LLC
IVF - Luteal Phase Support After Embryo Transfer
A Prospective Randomized Multicentre Study to Compare Crinone 8% Once Daily Versus Other Vaginal Progesterone.
To compare the effect of Crinone 8% administered once daily versus other vaginal progesterone in terms of ongoing pregnancy rate 5 weeks after embryo transfer as well as patient convenience.
- Trial name
- NCT00708539
- Testing
- progesterone
- Where
- 17 sites in Denmark, Sweden
- Volunteers
- 2,686 people
- Sponsor
- Nordica Fertility Clinic
Infertility
The Effect of Baseline Bilateral Uterine Artery Doppler Velocimetry on Obstetric Outcomes in HRT-FET Cycles
Researchers aim to determine how baseline (pre-conceptional) uterine perfusion characteristics affect implantation rates and obstetric complications in women who underwent high-quality blastocyst transfer.
- Trial name
- NCT05526014
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Embryo Transfer, IVF
Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
- Conditions
- Embryo Transfer, IVF, Infertility
- Trial name
- NCT07499817
- Testing
- pentoxifylline 400 mg, (control)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
IVF, ICSI
Randomized Prospective Trial on the Use of Laser Assisted Hatching (LAH) for Transfer of Frozen/Thawed Embryos in Human IVF/ICSI
At the time of transfer of frozen/thawed embryos in human IVF/ICSI, patients are randomized between study and control group.In the control group no additional intervention takes place on the embryos to be transferred,in the study…
- Trial name
- NCT00561249
- Testing
- laser assisted hatching
- Where
- Belgium
- Volunteers
- 293 people
- Sponsor
- University Hospital, Ghent
Infertility
PGS Using Microarray in IVF Patients With Repeated Implantation Failure
This project intends to use preimplantation genetic screening (PGS) with the microarray technique to determine the chromosome composition of fertilized eggs, so that only chromosomally normal embryos are transferred during IVF.
- Trial name
- NCT02265614
- Testing
- PGS
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- IVF Research Sweden
Infertility
The Effect of Embryo Culture Under a Continuous CO2 Setting Versus a Sequential CO2 Setting
The purpose of this study is to determine if embryo culture under a single CO2 setting improves blastocyst formation rate.
- Trial name
- NCT04693806
- Testing
- Continuous CO2 Level
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Prolutex in Frozen Embryo Transfer Cycles At the Blastocyst Stage (PROGEX)
The objective of this proof of concept clinical trial is to evaluate the impact of two different progesterone treatments for endometrial preparation (25 mg/twice-a-day, subcutaneous injection, and 200 mg/three times a day…
- Trial name
- PROGEX (NCT03701490)
- Testing
- Progesterone subcutaneous, Progesterone Vaginal Product
- Where
- 3 sites in Spain
- Volunteers
- 213 people
- Sponsor
- IBSA Institut Biochimique SA
Clinical Pregnancy Rate
Does the Volume of the Embryo Culture Medium During Embryo Transfer Affects the IVF Outcomes?
The aim of this study was to evaluate if higher volume (40-45μl VS 20-25 μl) of media used for embryo transfer affects the clinical outcomes in fresh IVF cycles.Patients who fulfilled the inclusion criteria and agreed to…
- Trial name
- NCT03350646
- Testing
- Volume of medium during embryo transfer
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
Sterility
Endometrial Priming for Embryo Transfer
The aim of this trial is compare two different endometrial priming protocols women that receive oral estrogens women that receive transdermal estrogens
- Trial name
- NCT01430650
- Testing
- Oral strogen, Transdermal strogen
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Parc de Salut Mar
Pregnancy
Acupuncture, Chinese Traditional Medicine, in Embryo Transfer
The aim of the study is to prove that acupuncture applied before and after embryo transfer is able to increase pregnancy rates by means of reducing stress and improving endometrial vascularization in women receiving in vitro…
- Trial name
- NCT01449396
- Testing
- Bed Rest, Acupuncture
- Where
- Spain
- Volunteers
- 286 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Infertility
Freeze All Protocol Versus Fresh Embryo Transfer in Women Undergoing In-vitro Fertilization (IVF)
To compare the effectiveness of freeze-all and subsequent frozen embryo transfer (freeze all protocol) with fresh embryo transfer (fresh ET).
- Trial name
- NCT02471573
- Testing
- Freeze-all protocol, Fresh transfer protocol
- Where
- Vietnam
- Volunteers
- 782 people
- Sponsor
- Vietnam National University
Stargardt's Macular Dystrophy
A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)
The purpose of this study is to evaluate the long term safety and tolerability of hESC-RPE cellular therapy in patients with advanced SMD from 1 to 5 years following the surgical procedure to implant the hESC-RPE cells.
- Trial name
- NCT02941991
- Testing
- hESC-RPE
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- Astellas Institute for Regenerative Medicine
Recurrent Implantation Failure
Zishen Yutai Pill for Patients With Recurrent Implantation Failure
The goal of this clinical trial is to evaluate the efficacy of Zishen Yutai Pill (ZYP) on pregnancy outcomes following embryo transfer and its safety in patients with recurrent implantation failure.
- Trial name
- NCT07641088
- Testing
- Zishen Yutai Pill
- Where
- 13 sites in China
- Volunteers
- 878 people
- Sponsor
- Peking University Third Hospital
Fertility
Natural Cycle Versus Stimulated Cycle Before Frozen Embryo Transfer
Embryo freezing is a technique used regularly to optimize the pregnancy rate in case of infertility. This method is performed in presence of supernumerary embryo(s) after fresh transfer, or after freeze all embryos in case of…
- Trial name
- SONTEC (NCT02834117)
- Testing
- natural cycle, moderate ovarian stimulation
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Dr Massin Nathalie