Clinical trials: Embryo Growth Disorder
Infertility
Use of GM-CSF Supplemented IVF Medium in Patients With Recurrent Implantation Failure
The purpose of this study is to determine whether in Assisted Reproductive Technologies the use of culture medium supplemented with GM-CSF, a growth factor working on stem cells, may improve the embryo implantation in patients…
- Trial name
- NCT01718210
- Testing
- GM-CSF medium, CONTROL
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Infertility, Female
Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF
The purpose of this study is to investigate the effect of G-CSF on endometrial thickness in women who have failed reaching minimal endometrial thickness by standard treatments, to assess how many reach embryo transfer and what…
- Trial name
- NCT01202643
- Testing
- G-CSF, Saline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Thin Endometrium, Infertility Female
Effectiveness of Intrauterine Growth Hormone Administration as an add-on Therapy to Conventional Hormone Therapy Compared to Placebo in Patients With Thin Endometrium Undergoing Frozen Thawed Embryo Transfer
The purpose of this clinical trial is to see if intrauterine growth hormone infusions can help subjects reach a suitable endometrial thickness in patients who are resistant to routine hormonal therapy for embryo transfer in the…
- Conditions
- Thin Endometrium, Infertility Female, Infertility
- Trial name
- NCT06379659
- Testing
- Growh hormone
- Where
- Iran
- Volunteers
- 54 people
- Sponsor
- Isfahan University of Medical Sciences
Infertility, Poor Ovarian Reserve
Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score
Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.
- Conditions
- Infertility, Poor Ovarian Reserve, Embryo Growth Disorder, in Vitro Fertilization
- Trial name
- NCT07020546
- Testing
- Ovarian Platelet-rich plasma (PRP) injections
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Generation Next Fertility
Embryo Growth Disorder, Humans
Impact of PH Values of the Embryo Culture Medium on Success of in Vitro Fertilization (IVF)
The objective of this study is to compare, through a multicentric randomized trial, the impact of two pH values in the embryo culture medium on the clinical results of In Vitro Fertilization (IVF) process and especially the…
- Conditions
- Embryo Growth Disorder, Humans, Pregnancy
- Trial name
- ACIDOFIV (NCT04456478)
- Testing
- pH at 7.38 ± 0.02, pH at 7.22 ± 0.02
- Where
- 3 sites in France
- Volunteers
- 429 people
- Sponsor
- University Hospital, Toulouse
Infertility, Infertility, Female
Concentrate of Autologous Rich Plasma in Growth Factors in the Treatment of the Thin Endometrium
This study evaluate the percentage of women with thin endometrium who achieve an endometrial thickness equal to or greater than 7 mm after administration of PRGF (plasma rich in growth factors)
- Trial name
- APTE (NCT03387501)
- Testing
- Plasma rich in growth factors (PRGF-Endoret)
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Sara Rafael Fernandez
Colorectal Cancer Metastatic, Tumour Metastasis
Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model
In order to improve and individualize cancer treatment, personalized treatment needs to be developed much further. Liver metastasizing colorectal cancer is treated with a combination of oncological and surgical interventions.
- Conditions
- Colorectal Cancer Metastatic, Tumour Metastasis, Chemotherapy Effect, Tumor Growth
- Trial name
- CRLM-Z (NCT05289076)
- Testing
- Chemotherapy drug
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- University Hospital, Linkoeping
Polycystic Ovary Syndrome
Clinical Observation of Recombinant Human Growth Hormone Injection Assisted IVF-ET in the Treatment of PCOS
Observe validity of Recombinant Human Growth Hormone Injection assisted in IVF-ET (in vitro fertilization and embryo transfer) treatment of PCOS (polycystic ovary syndrome) patients.
- Trial name
- NCT02801565
- Testing
- Conventional controlled ovarian stimulation proctol
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Infertility,Female
Growth Hormone Adding to Controlled Ovarian Hyperstimulation for Improving Embryo Quality
GH plays an important role in the synthesis of ovarian steroid hormone and follicular development as a paracrine hormone.GH can regulate the growth hormone receptor and strengthen the function of mitochondria to improve the…
- Trial name
- NCT03966339
- Testing
- Growth hormone
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya