Clinical trials: Embryonal Neoplasm
Glioma
IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma
This is an open-label positron emission tomography/near infrared (PET/NIRF) study to investigate the imaging navigation performance and evaluation efficacy of dual modality imaging probe 68Ga-BBN-IRDye800CW in patients with lower…
- Trial name
- NCT03407781
- Testing
- 68Ga-BBN-IRDye800CW
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Deling Li
Head and Neck Cancer
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00898638
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Melanocytic Nevi (MN)
Pregnancy-related Changes in Melanocytic Nevi
This study is to analyze whether more changes in melanocytic nevi (MN) occur in women during and after pregnancy compared to non-pregnant women of the same age and to analyze psychological effects of total body mapping and…
- Trial name
- NCT05148455
- Testing
- standard-of-care clinical skin examination, skin assessment with the 2D FotoFinder ATBM master system, data collection by participant questionnaire
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Volunteers, Recurrent Glioma
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
This first-in-human study will establish the human safety and radiation dosimetry of the system A amino acid transport substrate, (R)-3-[F-18]fluoro-2-methyl-2-(methylamino)propanoic acid ([F-18]MeFAMP), for positron emission…
- Conditions
- Healthy Volunteers, Recurrent Glioma, Brain Metastases From Extra-cranial Solid Tumors
- Trial name
- NCT05676489
- Testing
- [F-18]MeFAMP PET
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Melanoma
Tailored Intervention for Melanoma Patient's Families
The purpose of the investigators' study is to find the best way to provide information about sun protection and skin cancer detection.
- Trial name
- NCT00816374
- Testing
- Reading materials and discussions, Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cancer, Lung Cancer
Social Prescriptions and Micro-Learning to Improve Care for Cancer Patients and Their Support Persons
Optimal patient-centered care is often not being delivered to cancer patients, especially to vulnerable populations like those living in underserved rural areas.
- Conditions
- Cancer, Lung Cancer, Colorectal Cancer, Hematological Cancer
- Trial name
- PRISMA (NCT07788729)
- Testing
- PRISMA-interventions
- Where
- 8 sites in Germany
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Neuroblastoma
A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma
The purpose of the study is to explore the combination of a bivalent vaccine, a sugar called beta-glucan (β-glucan), and a protein called granulocyte-macrophage colony stimulating factor (GM-CSF) as an effective treatment for…
- Trial name
- NCT04936529
- Testing
- β-glucan, GM-CSF, OPT-821
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Melanoma (Skin)
Effectiveness of Group and Individual Training in EFT for Patients in Remission From Melanoma
Serious medical diagnosis frequently induce fear focused on specific anticipations or generalized anxiety, along with uncertainty, insecurity, and disorientation.
- Trial name
- NCT05421988
- Testing
- Emotional Freedom Techniques (EFT)
- Where
- Israel
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Metastatic Melanoma
Melanoma Biomarker Study
The purpose of this study is to measure the level of a specific protein, CXCL1, in the blood of patients with untreated, metastatic (Stage IV) melanoma. These levels will be compared to blood levels in normal controls.
- Trial name
- NCT00348088
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Melanoma
Digital vs. Printed Photographs: Impact on Skin Self-Examinations
The primary aim is to determine the impact of using digital photographs on a mobile device versus printed photographs on skin self-examination rates.
- Trial name
- NCT02520622
- Testing
- Digital photographs loaded onto a mobile device, Skin exam reminders, Social support network
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Melanoma (Skin)
Biomarkers to Predict Response to Interferon Therapy in Patients With Melanoma
RATIONALE: Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer, and may help…
- Trial name
- NCT00897546
- Testing
- laboratory biomarker analysis
- Volunteers
- 1,716 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Metastatic Olfactory Neuroblastoma, Recurrent Olfactory Neuroblastoma
A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma
To learn if rivoceranib can help to control olfactory neuroblastoma. The safety of this drug in participants with olfactory neuroblastoma will also be studied.
- Trial name
- NCT06308575
- Testing
- Rivoceranib
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Melanoma (Skin), Skin Cancer
Investigation of a Behavioral Substitute for Sunbathing
RATIONALE: Understanding why sunbathers use or don't use sunless tanning products may help doctors plan effective ways to prevent skin cancer caused by sunbathing.
- Trial name
- NCT00403377
- Testing
- Intervention
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pheochromocytoma, Paraganglioma
Hereditary Pheochromocytoma Assessment of Tumour Immunologies
In this study, the investigators are examining the role of the immune system in pheochromocytoma and paraganglioma. The investigators aim to examine the differences in the immune system between people who have these tumors with…
- Trial name
- HEPHESTOS (NCT06444607)
- Testing
- Venepuncture
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy Participants With Different Skin Types and Different Ages, Diseased Participants With Different Skin Types and Different Ages
Harmonics-based in Vivo Optical Virtual Biopsy
The research aims to study the molecules and structures in human skin by the image formation of harmonic-based in vivo optical virtual biopsy.
- Conditions
- Healthy Participants With Different Skin Types and Different Ages, Diseased Participants With Different Skin Types and Different Ages, Participants Suffered From Diabetes With Different Skin Types and Different Ages
- Trial name
- NCT01980264
- Testing
- Harmonic Generation Microscopy
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer, Pancreatic Adenocarcinoma
Circulating Tumor DNA Exposure in Peripheral Blood
This is a prospective, multi-center, blinded feasibility study. The objective of this study is to test the feasibility of the detection of tumor DNA of a variety of tumors in peripheral blood using a novel process for the…
- Conditions
- Colorectal Cancer, Pancreatic Adenocarcinoma, Gastric Cancer, Hepatocellular Carcinoma
- Trial name
- NCT03517332
- Where
- 6 sites in United States, Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Quantgene Inc.
Chordoma, Chemotherapy Effect
Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma
This phase II trial studies how well Camrelizumab combined with Apatinib work in treating participants with chordoma that has spread to other places in the body, which may interfere with the ability of tumor cells to grow and…
- Trial name
- NCT06140732
- Testing
- camrelizumab and apatinib
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Brain Tumor, Glioma
Gliogene: Brain Tumor Linkage Study
The goal of this research study is to investigate the role of genes that may point to a higher risk of developing a glioma. Researchers will use new gene mapping techniques to study how high-risk factors are passed on through a…
- Trial name
- NCT00418899
- Testing
- Questionnaire
- Where
- 15 sites in United States, Denmark and 4 more
- Volunteers
- 17,080 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostatic Neoplasms, Glioma
PET/CT Imaging Study With Simultaneous Dual-nuclide Imaging Technique
This is a study using a parallel control approach and is expected to recruit 35 volunteers, including 8 prostate cancer patients, 8 neuroendocrine tumour patients, 8 glioma patients, 8 Parkinson's syndrome patients, and 3 normal…
- Conditions
- Prostatic Neoplasms, Glioma, PARKINSON DISEASE (Disorder)
- Trial name
- NCT06914427
- Testing
- PET/CT
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Glioblastoma Multiforme, Anaplastic Astrocytoma
Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma
This study will offer a safe treatment for patients with relapsing recurring glioblastoma (GBM) or anaplastic astrocytoma (AA). The trial will test the hypothesis that Erlotinib (Tarceva, OSI-774) can be safely used up to a dose…
- Trial name
- NCT00301418
- Testing
- Erlotinib
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Northwell Health