Clinical trials: Emdogain
Chronic Periodontitis, Periodontal Bone Loss
Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration.
The aim of this study is to compare the effectiveness in periodontal regeneration of cross-linked hyaluronic acid at 1.8% (Hyadent BG®) with enamel matrix derivative (Emdogain®) in periodontal bone defects evaluating their…
- Trial name
- NCT04274244
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML, Enamel Matrix Proteins (Active comparator group)
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- Andres Lopez Roldan
Periodontitis, Intrabony Periodontal Defect
Effectiveness of Hyaluronic Acid (hyaDENT BG® Gel) Compared With Enamel Matrix Proteins (Emdogain®) in the Treatment of Angular Bone Defects in Combination With a Xenograft (Bio-Oss Collagen®)
The goal of this clinical trial is to learn whether hyaluronic acid (HyaDent® BG) provides similar benefits to Emdogain® when both are used with Bio-Oss® Collagen during periodontal surgery in adults with periodontal (intrabony)…
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Bone Loss
- Trial name
- NCT07230522
- Testing
- Bio-Oss Collagen + HyaDent BG, Bio-Oss Collagen + Emdogain
- Where
- Bulgaria
- Volunteers
- 17 people
- Sponsor
- Medical University of Sofia
Chronic Periodontitis, Generalized
Flapless Emdogain in the Treatment of Periodontal Residual Pockets
48 adult patients participated in a single-centre randomized clinical trial with split- mouth design. They had presented at re-evaluation after initial non-surgical periodontal therapy (steps 1 and 2 of periodontal therapy) for…
- Trial name
- NCT05823389
- Testing
- Re-instrumentation with flapless Emdogain application
- Where
- Palestinian Territories
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Periodontitis
Emdogain Minimally Invasive Surgical Technique
The aim of this controlled study is to assess the clinical outcomes and patient reported outcomes of using minimally invasive surgical procedure with Straumann Emdogain as an adjunct (test treatment) or without Straumann Emdogain…
- Trial name
- NCT02551770
- Testing
- Scaling and root planing, Scaling and root planing without Emdogain, Emdogain application
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Intrabony Periodontal Defect
Rh-PDGF vs EMD for Treatment of Intra-bony Defects
Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects.
- Trial name
- NCT05442034
- Testing
- growth factors to help in regeneration
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Periodontitis
Effectiveness of Adjunctive Therapy of Emdogain®FL in Non-surgical Periodontal Treatment
The goal of this clinical trial is to assess the safety and effectiveness of adjunctive Emdogain® therapy in non-surgical periodontal treatment for patients with stage 3 and 4 periodontitis.
- Trial name
- NCT06070181
- Testing
- Enamel matrix derivate, Non-surgical periodontal treatment
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Ostergotland County Council, Sweden
Periodontal Inflammation, Crown Lengthening
Effect of Emdogain® on Soft Tissue Wound Healing
The goal of this randomized, controlled, single-center study is to compare the effects of Emdogain®, a regenerative biomaterial, on post-operative pain, wound healing and inflammation of treated sites after surgical crown…
- Trial name
- NCT06179277
- Testing
- PrefGel® + Emdogain®, PrefGel®
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amir Azarpazhooh
Peridontal Disease, Furcation Defects
PRF Versus Emdogain for Class II Furcation Defects of Mandibular Molars
This study evaluated the regenerative potential of platelet-rich fibrin (PRF) compared with enamel matrix derivative (Emdogain®) in the surgical treatment of Class II (F2) furcation defects of mandibular molars.
- Trial name
- NCT07841301
- Testing
- Platelet rich fibrin, Emdogain
- Where
- Bulgaria
- Volunteers
- 21 people
- Sponsor
- Medical University of Sofia
Gingival Recession
Tunnel Technique With Emdogain® in Addition to Connective Tissue Graft Compared With Connective Tissue Graft Alone for the Treatment of Gingival Recessions: a Randomized Clinical Trial.
Microsurgical tunneling flap procedures using connective tissue grafts (CTG) are predictable for treating teeth with gingival recessions.
- Trial name
- NCT03354104
- Testing
- The tunnel technique for root coverage with Emdogain, The tunnel technique for root coverage without Emdogain
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Warsaw
Periodontal Attachment Loss, Periodontal Diseases
Safety and Efficacy of Periodontal Surgery in Supra-alveolar-type Defects With or Without Straumann® Emdogain
The primary objective of this study is to demonstrate that in supra-alveolar-type defects (i.e., defects displaying a predominately horizontal pattern of bone loss), periodontal surgery with the additional use of Straumann®…
- Trial name
- NCT01614925
- Testing
- Emdogain, Periodontal surgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Institut Straumann AG
Gingival Recession
Evaluation of the Inflammatory and Healing Profile After Root Coverage With Emdogain®
The purpose of this study was the evaluation of inflammatory and healing profile after root coverage using of Enamel Matrix Derivative.
- Trial name
- NCT03059966
- Testing
- Microsurgery technique for root coverage, Microsurgery technique for root coverage associated to EMD
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Tooth Loss
Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region
This randomized clinical trial will evaluate the effect of using an enamel matrix derivative during immediate dental implant placement in the mandibular molar region.
- Trial name
- NCT07727655
- Testing
- Enamel Matrix Derivative (Emdogain), Immediate Dental Implant Placement
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Gingival Recession, Emdogain
Gingival Recession Coverage With and Without Emdogain
Enamel matrix proteins have been shown to play a crucial role during tooth development and its supporting tissues. This is used in periodontal surgery where regeneration of lost tissues around the teeth is intended.
- Trial name
- NCT02230787
- Testing
- Recession coverage without Emdogain, Recession coverage with Emdogain
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Non-vital Immature Anterior Teeth
Comparison Between Emdogain and Amniotic Membrane as a Scaffold in Endodontic Regeneration of Immature Anterior Teeth
To evaluate the clinical outcomes and cone-beam computed tomography findings of enamel matrix derivative and amniotic membrane in regenerative endodontic treatment of non-vital immature permanent anterior teeth
- Trial name
- NCT07252167
- Testing
- Regenerative endodontic treatment with conventional blood clot technique., regenerative endodontic treatment with emdogain., regenerative endodontic treatment with amniotic membrane
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Al-Azhar University
Periodontitis, Periodontal Bone Loss
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects
The present study pretends to show the results of combining a modification of the Non-incised papillae surgical approach (NIPSA) attempting to improve the outcome in the treatment of teeth with advanced periodontal support loss.
- Conditions
- Periodontitis, Periodontal Bone Loss, Periodontal; Lesion
- Trial name
- NCT03997578
- Testing
- NIPSA (Non-incised papilla surgical approach), NIPSA plus connective tissue graft
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Murcia
Periodontal Disease, Periodontal Attachment Loss
Study on Regenerative Treatment of Intra-bony Defects
The aim of this investigation is to determine whether a synthetic hydroxyapatite is as effective as an enamel matrix protein for periodontal regeneration in patients who have intra-bony periodontal defects.
- Trial name
- NCT00757159
- Testing
- Ostim, Emdogain
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Technische Universität Dresden
Class II Furcation Defect
Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation Defects
This randomized controlled clinical trial aims to compare two regenerative surgical approaches for the treatment of mandibular molar Class II furcation defects in patients with periodontitis.
- Trial name
- NCT07776756
- Testing
- Periodontal Regenerative Surgery With Xenograft and Enamel Matrix Derivative, Periodontal Regenerative Surgery With Xenograft and Collagen Membrane
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Autotransplantation, Emdogain
Emdogain Adjunctive to Autotransplantation
The goal of this randomized clinical trial is to compare the adjunctive use of enamel matrix derivatives in the treatment of tooth autotransplantation in terms of clinical attachment level. The main question it aims to answer.
- Conditions
- Autotransplantation, Emdogain, Autologous Transplantation, Enamel Matrix Derivatives
- Trial name
- ATTEMD (NCT06250088)
- Testing
- Emdogain (EMD) - test
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Periodontitis
Emdogain and Straumann Bone Ceramic in Infrabony Defects
Randomised, controlled, clinical study to compare the effect of the combination of bone ceramic and enamel matrix proteins (test) versus autogenous bone graft alone (control) in the treatment of deep-wide intrabony defects
- Trial name
- NCT00906776
- Testing
- Emdogain PLUS, Autogenous bone
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Institut Straumann AG
Periodontitis, Regeneration
Modified Entire Papilla Preservation Technique For Treatment Of Intrabony Defects. Clinical Trial.
Regeneration of periodontal tissues is the primary goal of periodontal surgery regenerative procedures. Most techniques include an incision of the interdental papilla associated with defect.
- Trial name
- MEPPT (NCT05029089)
- Testing
- Modified Entire Papilla Preservation Technique (MEPPT) For Periodontal Regenerative Treatment Of Intrabony Defects., Emdogain (EMD), Biomaterials (allograft, subepithelial connective tissue graft/sCTG), Modified Entire Papilla Preservation Technique (MEPPT) with Emdogain For Periodontal Regenerative Treatment Of Intrabony Defect
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw