Clinical trials: Emergencies
Dehydration, Seizure
Point of Care Device Use in the Pediatric Emergency Department
To compare the effect of "point-of-care" (POC) analysis of blood work with traditional laboratory methods on length of stay in a pediatric emergency department (PED).
- Conditions
- Dehydration, Seizure, Gastroenteritis, Hyperglycemia
- Trial name
- NCT00285285
- Testing
- Point of Care Device; i-Stat Analyzer
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Hemolysis, Blood Specimen Collection
Clinical Study of a Novel Hemolysis Point of Care Test at an Emergency Department.
This study aims to investigate the outcome of hemolysis frequency when a hemolysis point of care test is introduced in an emergency department.
- Trial name
- NCT02976610
- Testing
- Hemolysis Point-of-Care test
- Where
- Sweden
- Volunteers
- 1,671 people, healthy volunteers welcome
- Sponsor
- Hemcheck Sweden AB
Acute Illness
Degree-of-worry and Illness Perception in Patients Suffering From Acute Illness in the Emergency Department
This study explores whether and how DOW, as a PRO marker, can contribute to triage in the Emergency Departments. The study is designed as a mixed-method study consisting of a survey among acutely ill patients and qualitative…
- Trial name
- NCT04226040
- Testing
- DOW and illness perception
- Where
- Denmark
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Drug Abuse
Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department
Screening, brief interventions, and referral to treatment (SBIRT) for drug use/abuse offers opportunities for early detection, brief intervention/treatment, and substance use treatment referrals for patients in medical settings.
- Trial name
- NCT01113190
- Testing
- Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
- Where
- United States
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- University of Michigan
COVID 19 Vaccine
Combination Assessment Trial of COVID-19 Vaccines (COMBAT-COVID)
This is a randomized, phase II trial which will be conducted among volunteers aged 18 years and above in Karachi, Lahore and Islamabad, Pakistan. The trial will have nine arms and is an open label study.
- Trial name
- COMBAT-COVID (NCT05162482)
- Testing
- BIBP (CNBG, Sinopharm) WIV, CanSinoBIO, AstraZeneca ChAdOx
- Where
- 3 sites in Pakistan
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Acute Coronary Syndrome
Improving the Management of Acute Coronary Syndromes in the Emergency Department
By using a Rapid Cardiac Evaluation (RACE) pathway in the Emergency Department (ED), the investigators can effectively reduce ED wait times and ED length of stay by decreasing overall hospital admissions and telemetry admissions.
- Trial name
- RACE (NCT01563250)
- Testing
- Point of Care testing
- Where
- United States
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Integrated Medical Research LLC
Obesity
Effects of Obesity on Pharmacokinetics of the Levonorgestrel Emergency Contraceptive Pill
The purpose of this study is to determine the effects of obesity on the pharmacokinetics of the levonorgestrel (LNG) only emergency contraceptive (EC) regimen and on markers of ovulation Primary hypothesis: 1) Obese users of…
- Trial name
- NCT02104609
- Testing
- Levonorgestrel 1.5mg by mouth once
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Status Epilepticus
Improving Emergency Management of Status Epilepticus
In the trial the effectiveness of pre-briefing physicians with the current guideline on Status epilepticus (SE) treatment or a consolidated "one page" guideline regarding quality enhancement of the physician's clinical…
- Trial name
- SESIM (NCT03883516)
- Testing
- Pre-briefing with the current SE treatment guidelines, Pre-briefing with a consolidated "one page" SE treatment guide, No Pre-briefing
- Where
- Switzerland
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Blindness
Emergency Egress and Information System for Persons With Vision Loss
The purpose of the research project is to develop and evaluate an emergency egress system for persons with visual impairment, which would use existing lighted exit signage to provide egress information at a distance of up to 100…
- Trial name
- NCT00262509
- Testing
- Egress Badge
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Trichomonas Vaginitis, Chlamydia Trachomatis
Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing
The purpose of this study is to determine the prevalence and treatment rates of T. vaginalis, C. trachomatis, and N. gonorrhoeae in women seeking emergency contraception or urine pregnancy testing in the Magee-Womens Hospital…
- Conditions
- Trichomonas Vaginitis, Chlamydia Trachomatis, Neisseria Gonorrhoeae Infection
- Trial name
- NCT00978848
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Contraception
Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
We hypothesize that administration of OCs at varying follicular diameters will provide an appropriate model for the study of follicular atresia in women.
- Trial name
- NCT00204438
- Testing
- 0.15mg desogestrel /0.03mg ethinyl estradiol
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Acute Stress Disorder, Anxiety
Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room
The hypothesis is that intranasal dexmedetomidine will provide significantly more effective analgesia and anxiolysis for subjects undergoing a simple laceration repair when compared to either intranasal fentanyl or intranasal…
- Conditions
- Acute Stress Disorder, Anxiety, Pain
- Trial name
- NCT05057689
- Testing
- Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Sepsis, Oxidative Stress
Sepsis and Thiol-Disulfide Balance in Emergency Department
The aim of this study was to determine the effectiveness of thiol-disulfide homeostasis in predicting diagnosis and mortality in sepsis patients, and to compare it with other inflammatory markers.
- Trial name
- NCT07134868
- Testing
- Thiol- Disulfide Blood Sample Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Trauma Injury, Haemorrhagic Shock
Prediction of Massive Transfusion in Trauma Patients
Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers.
- Conditions
- Trauma Injury, Haemorrhagic Shock, Bleeding, Emergencies
- Trial name
- MTP (NCT04561050)
- Testing
- Comparison of score performances (Overall performance, discrimination and calibration)
- Where
- Switzerland
- Volunteers
- 13,222 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Emergency Service, Hospital, Social Determinants of Health
Predictive Modeling for Social Needs in Emergency Department Settings
The overall objective of this study is to support emergency department management of patients' health-related social needs. This study will measure the impact of a decision support system that informs clinicians about which…
- Trial name
- NCT06655974
- Testing
- Health-related social needs decision support system
- Where
- United States
- Volunteers
- 518,512 people, healthy volunteers welcome
- Sponsor
- Indiana University
Emergency Medical Services, Triage
Reliability of the Swiss Emergency Triage Scale (SETS®) Used by Emergency Medical Service (EMS) Providers
The Swiss Emergency Triage Scale (SETS) in used for triage in emergency departments in Switzerland, France and Belgium. No validated triage scale is actually used by Emergency Medical Service (EMS) providers.
- Trial name
- NCT02559531
- Testing
- Mobile triage system
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
COVID-19, Coronavirus
Will Hydroxychloroquine Impede or Prevent COVID-19
This is a prospective, multi-site study designed to evaluate whether the use of hydroxychloroquine in healthcare workers (HCW), Nursing Home Workers (NHW), first responders (FR), and Detroit Department of Transportation bus…
- Conditions
- COVID-19, Coronavirus, Coronavirus Infections, SARS-CoV 2
- Trial name
- WHIP COVID-19 (NCT04341441)
- Testing
- Hydroxychloroquine - Daily Dosing, Hydroxychloroquine - Weekly Dosing, Monitoring Visit - Baseline
- Where
- United States
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
HIV Testing
Increasing HIV Testing in Urban Emergency Departments Via Mobile Technology
Because people with undiagnosed HIV will not receive treatment and may unknowingly infect others, the investigators propose a mobile computer-based video intervention to increase HIV test rates in high volume urban hospital…
- Trial name
- NCT02154802
- Testing
- video: community member, video: physician, video: choice of video
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Development and Research Institutes, Inc.
Blood Loss
The MAR Method Versus the Visual Estimation Method in Predicting External Blood Loss
The goal of this educational clinical trial is to determine whether the MAR method is more effective than the Visual Estimation method for estimating blood loss.
- Trial name
- NCT06855472
- Testing
- The MAR method
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Betül Akbuğa Özel
Maternal, Pediatric Care Emergencies
Does Simulation Scenario Execution Improve Acute Care Skills and Confidence Related to Maternal and Pediatric Care Emergencies?
In Uganda and many countries in Sub-Saharan Africa, health providers have minimal training and intermittent opportunity to maintain skills in managing delivery complications and acute newborn and pediatric conditions.
- Trial name
- SimForLife (NCT03258073)
- Testing
- Medical simulation using scenario execution
- Where
- Uganda
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology