Clinical trials: Emergencies
Renal Colic, Kidney Stone
Erector Spinae Plane Block for Uncomplicated Renal Colic
This research study is to determine how well the Erector Spinae Plane Block (ESPB) works for kidney stone pain and any possible side effects.
- Trial name
- NCT05625802
- Testing
- Erector Spinae Plane Block (ESPB), Ropivacaine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Musculoskeletal Pain, Analgesia
Intramuscular Ketorolac at Two Single-Dose Regimens
The purpose of this study was to evaluate a single 15 mg intramuscular (IM) dose of ketorolac for analgesic non-inferiority versus a single 60 mg IM dose for the treatment of acute MSK pain in a military emergency department (ED)…
- Conditions
- Musculoskeletal Pain, Analgesia, Adverse Event
- Trial name
- NCT04763876
- Testing
- Ketorolac Injection 15 mg, Ketorolac Injection 60 mg
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Children Who Present to the ED With Minor Febrile Illnesses
Video Discharge Instructions for Fever and ED Recidivism
To evaluate the effect of video discharge instructions on return visits to the ER or ED within 72 hours of the original visit for children with febrile illnesses.
- Trial name
- NCT01655251
- Testing
- Intervention
- Where
- 2 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Alcohol Use Disorder
ED Initiated Oral Naltrexone for AUD
This study will recruit Emergency Department (ED) patients with moderate to severe alcohol use disorder (AUD) who are interested in initiating medication assisted treatment (MAT). The study is split into two phases.
- Trial name
- NCT04817410
- Testing
- Emergency Department Initiated Oral Naltrexone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Other Acute Pain
An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain
The purpose of this study is to determine the effectiveness, the safety, and the tolerability of intranasal ketorolac (Sprix) in relieving acute pain in adults ages 18-65 who come to the ED seeking care.
- Trial name
- Sprix (NCT01471639)
- Testing
- intranasal ketorolac
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- The Cleveland Clinic
Dementia, Caregiver
Artificial Intelligence + Care Coach Intervention
The purpose of this research study is to develop and test an artificial intelligence intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Artificial Intelligence
- Trial name
- NCT05352399
- Testing
- NeuViCare application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Emergencies
Primary Palliative Care for Emergency Medicine (PRIM-ER)
This proposal builds upon the evaluation of Primary Palliative Care Education, Training, and Technical Support for Emergency Medicine (PRIM-ER) implemented in a cluster-randomized, stepped wedge design in 33 Emergency Departments…
- Trial name
- NCT03424109
- Testing
- healthcare service utilization in the six months following the ED visit
- Where
- United States
- Volunteers
- 98,922 people
- Sponsor
- NYU Langone Health
Hypertension, Cardiovascular Diseases
Targeting of UnControlled Hypertension in Emergency Department
The proposed project underscores the following: 1) The prevalence of uncontrolled/undiagnosed hypertension (HTN) in underrepresented groups presenting to the ED is alarmingly high, and 2) ED engagement and early risk…
- Conditions
- Hypertension, Cardiovascular Diseases, Vascular Diseases
- Trial name
- TOUCHED (NCT03749499)
- Testing
- HTN Educational Video, Visual Echocardiogram Image Clips, Mobile Health and Remote BP monitoring
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- University of Illinois at Chicago
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Migraine Disorders
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
Migraine is a neurological disease characterized by severe and recurrent headaches. Children and adolescents with migraine often present to the emergency department (ED) with acute attacks, where migraine accounts for up to ~30%…
- Trial name
- NCT05102591
- Testing
- Ketorolac, Metoclopramide, Active Remote Electrical Neuromodulation Device
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Triage
Triaging and Referring in Adjacent General and Emergency Departments
Introduction: Patients who might also go to the general practitioner (GP) frequently consult emergency departments (ED). This leads to additional costs for both government and patient and a high workload for emergency physicians…
- Trial name
- TRIAGE (NCT03793972)
- Testing
- Triage with referral to primary care, Usual care
- Where
- 2 sites in Belgium
- Volunteers
- 8,158 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Diabetic Ketoacidosis
Intravenous Fluids in Adults With Diabetic Ketoacidosis in the Emergency Department
Diabetes mellitus is a common chronic disease. It is estimated that up to 40% of adults may develop diabetes in their lifetime. Patients with poorly controlled blood sugars often visit the emergency department for treatment of…
- Trial name
- BRISK-ED (NCT04926740)
- Testing
- Ringer's lactate
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Disaster, Vulnerable Populations
Nurses Taking On Readiness Measures - Mercer County, New Jersey
Nurses Taking On Readiness Measures (N-TORM) is an innovative nurse-driven household emergency preparedness (HEP) intervention modeled after an existing community intervention provided by emergency management personnel.
- Trial name
- NTORM (NCT05455580)
- Testing
- Nurses Taking On Readiness Measures (N-TORM)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Pediatric Emergency Medicine, Communication
PIMPmyHospital: a Mobile App to Improve Emergency Care Efficiency and Communication
This pilot study is a prospective, single-center, randomized, controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary post-graduate year 1 to 5 pediatric residents and registered…
- Trial name
- NCT05203146
- Testing
- PIMPmyHospital (mobile health tool), Conventional method
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Adolescent Behavior, Emergency Department
Emergency Department Healthcare Education Assessment and Response for Teen Relationships: A Pilot Feasibility Study
This is a single-site, randomized, controlled trial. Investigators will evaluate feasibility of the Emergency Department Healthcare Education Assessment and Response for Teen Relationships (ED-HEART) intervention among…
- Conditions
- Adolescent Behavior, Emergency Department, Abuse Physical, Abuse Mental
- Trial name
- ED-HEART (NCT05194202)
- Testing
- ED-HEART
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Patient Experience, Medical Emergencies
Effectiveness and Clinical Outcomes of Municipal Acute Wards Versus a General Hospital
Demographic changes in the industrialized world are expected to prompt a need for better organized and more efficient health care services.
- Conditions
- Patient Experience, Medical Emergencies, Mortality, Morbidity
- Trial name
- NCT03885206
- Testing
- Level of healthcare services
- Where
- Norway
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Radiocontrast Nephropathy
N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients
Multiple agents have been studied to prevent radiocontrast nephropathy. One of these agents is N-Acetylcysteine. Previous trials to assess N-Acetylcysteine's efficacy in the prevention of contrast nephropathy have been promising.
- Trial name
- NCT00780962
- Testing
- N-Acetylcysteine (NAC), 0.9% Sodium-chloride
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Beth Israel Deaconess Medical Center
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Reproductive Behavior, Sexual Behavior
Reducing Teen Pregnancy in the Emergency Department
This study will determine the feasibility, acceptability, and potential efficacy of an emergency department-based pregnancy prevention intervention targeting sexually active adolescent female emergency department patients.
- Conditions
- Reproductive Behavior, Sexual Behavior, Adolescent Behavior, Contraception
- Trial name
- ERICA (NCT03866811)
- Testing
- Dr. Erica
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Columbia University
Emergency General Surgery
Development and Pilot Testing the SITe Intervention
Every year, nearly 240,000 patients age 60 and older are transferred between acute care hospitals for nontraumatic surgical emergencies, and these patients experience worse outcomes than patients admitted directly from an…
- Trial name
- NCT06118359
- Testing
- Intervention to Support Interhospital Transfer Decisions (SITe)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Wisconsin, Madison