Clinical trials: Emergency Department
Health Care Quality, Health Care Access
Telemonitoring Versus Usual Care
Background: Older adults with multiple chronic illnesses are at risk for worsening functional and medical status with ensuing hospitalization. One goal of medical care is to prevent this decline.
- Trial name
- NCT01056640
- Testing
- Intel Health Guide, Usual Care
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Infectious Diarrhea
Film Array Gastrointestinal Panel Compared to Usual Care for ED Evaluation of Infectious Diarrhea
This research study will test a laboratory test called Film-Array Gastrointestinal (GI) Panel. This GI Panel is a test that can identify the bacteria or viruses that may cause diarrhea.
- Trial name
- NCT03809117
- Testing
- Biofire Film Array Gastrointestinal Panel
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Andrew Meltzer
Alcohol Consumption, Unsafe Sex
Brief Interventions in the Emergency Department for Alcohol and HIV/Sexual Risk
This brief alcohol and sexual risk taking intervention has the potential to influence the public health by reducing alcohol use and sexual risk taking behavior in individuals who are seeking treatment in an Emergency Department.
- Trial name
- SAFER (NCT01351389)
- Testing
- Brief Motivational Intervention (BMI), Brief Advice
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Brown University
Asthma
Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)
The purpose of this study is to determine in a large, double-blind, randomized, prospective pediatric clinical trial whether the use of continuous levalbuterol (Xopenex) in addition to standard emergency department treatment for…
- Trial name
- Xopenex (NCT00585039)
- Testing
- xopenex
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Phoenix Children's Hospital
HIV Infections
HIV Screening in the Emergency Department Setting
Late diagnosis of HIV infection is believed to be responsible for high rates of HIV transmission. The purpose of this study is to determine whether targeted screening versus routine screening will identify a greater number of HIV…
- Trial name
- NCT00667186
- Testing
- Targeted Screening, Routine Screening
- Where
- United States
- Volunteers
- 9,572 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Agitation
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective treatment.
- Trial name
- NCT00457366
- Testing
- Quetiapine, Haloperidol, Lorazepam
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Dementia, Hip Pain
Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments
The purpose of this study is to learn if the Pain in Advanced Dementia (PAINAD) scale can improve emergency pain care in persons living with dementia (PLWD).
- Conditions
- Dementia, Hip Pain, Emergency Department Patient, Pain in Advanced Dementia Scale
- Trial name
- NCT06370572
- Testing
- PAINAD EHR Prompt
- Where
- 2 sites in United States
- Volunteers
- 2,421 people
- Sponsor
- University of Chicago
Pain
Geriatric Ketamine for Pain Management Study
This research project is geared towards geriatric analgesia in the Emergency Department (ED) with a goal of reducing the administration of opioid pain medications to elderly patients, thereby avoiding the commonly occurring…
- Trial name
- NCT02673372
- Testing
- Morphine, Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Antonios Likourezos
Respiratory Failure
Four Methods of Pre-oxygenation
Four methods of preoxygenation will be compared in healthy volunteers
- Trial name
- NCT02708862
- Testing
- Preoxygenation
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Opioid Dependence
Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments
This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients.
- Trial name
- NCT02586896
- Testing
- Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
Frail Elderly People
Continuum of Care for Frail Elderly People
The present study "Continuum of care for frail elderly people" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www.vardalinstitutet.net) which comprises research into three…
- Trial name
- NCT01260493
- Testing
- integrated health care chain
- Where
- Sweden
- Volunteers
- 181 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Sickle Cell Disease
Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease
The goal of this pilot study is to improve emergency department (ED) pain management for adults with sickle cell disease. Sickle cell disease (SCD) is the most common genetic disorder in the United States, and occurs primarily…
- Trial name
- NCT02222246
- Testing
- Hydromorphone (Standardized, weight-based dosing), Morphine Sulfate (Standardized, weight-based dosing), Hydromorphone (Patient Specific dosing)
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- Duke University
Acute Respiratory Failure
Randomized Trial of Sedative Choice for Intubation
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death.
- Trial name
- RSI (NCT05277896)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 2,367 people
- Sponsor
- Vanderbilt University Medical Center
Pain
The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast:
Intravenous contrast media is commonly used for CT scans for improved image clarity in pediatric emergency medicine. Children who feel discomfort during the administration of IV contrast media may not remain still during the CT…
- Trial name
- NCT05143489
- Testing
- Preservative Free Lidocaine, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Antonios Likourezos
COVID-19, Coronavirus
Will Hydroxychloroquine Impede or Prevent COVID-19
This is a prospective, multi-site study designed to evaluate whether the use of hydroxychloroquine in healthcare workers (HCW), Nursing Home Workers (NHW), first responders (FR), and Detroit Department of Transportation bus…
- Conditions
- COVID-19, Coronavirus, Coronavirus Infections, SARS-CoV 2
- Trial name
- WHIP COVID-19 (NCT04341441)
- Testing
- Hydroxychloroquine - Daily Dosing, Hydroxychloroquine - Weekly Dosing, Monitoring Visit - Baseline
- Where
- United States
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
External Causes of Morbidity and Mortality
Comparative Analysis of APACHE II and P-POSSUM
To compare APACHE II and P-POSSUM scoring system in emergency laparotomy.
- Trial name
- NCT02471612
- Where
- India
- Volunteers
- 159 people
- Sponsor
- Tata Main Hospital
Pain, Opiate
A Dosing and Efficacy Study of Intra-nasal Sufentanil for Moderate to Severe Pain
The purpose of this study is to determine the appropriate dose and effectiveness of intra-nasal administration of a potent narcotic, sufentanil, for the treatment of moderate to severe pain due to broken bone(s) in the arm or leg.
- Trial name
- NCT01012999
- Testing
- sufentanil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Pain
An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache
Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache. Most headaches managed in the ED are benign, with 90% of these headaches classified as tension, migraine, or cluster.
- Trial name
- NCT04860713
- Testing
- aspirin and ketamine, Nurtec (Rimegepant)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonios Likourezos
Skin and Soft Tissue Infections, Abscess
The Effect of Irrisept for Irrigation of Skin and Soft Tissue Infections (Irrisept USF Study)
The purpose of this study was to determine whether Irrisept can effectively prevent the progression of skin and soft tissue infections (SSTIs) as compared to treatment by the current Standard of Care.
- Trial name
- NCT01076049
- Testing
- Standard of Care (SoC), Irrisept Delivery System
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Irrimax Corporation
Pain
Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain
The hydromorphone protocol is more effective than usual care in Emergency Department (ED) patients age 65 years and older in terms of proportion who choose to forgo additional pain medication within 60 minutes post-baseline in…
- Trial name
- NCT01429285
- Testing
- Hydromorphone, Usual care
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center