Clinical trials: Emergency Department
Diverticulitis
Developing a Decision Tool for Diverticulitis in the Emergency Department Using Ultrasound
The purpose of this study is to create a decision tool using ultrasound, patient history, and laboratory values to predict a diagnosis of complicated diverticulitis and whether the patient requires further imaging.
- Trial name
- NCT05832242
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 1,125 people
- Sponsor
- Northwell Health
Mechanical Ventilation, Acute Respiratory Distress Syndrome
Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study
To prospectively assess the mechanical ventilation management when its provided by Emergency Physicians in French Hospital, and to assess complications and outcome of these patients.
- Conditions
- Mechanical Ventilation, Acute Respiratory Distress Syndrome, Protective Ventilation, Survival
- Trial name
- PARAVENT (NCT03351920)
- Testing
- mechanical ventilation
- Where
- 7 sites in France
- Volunteers
- 229 people
- Sponsor
- Poitiers University Hospital
Alcohol Use Disorder
Ketamine for the Treatment for Alcohol Use Disorder in the ED
The investigators' approach is to conduct a pilot double-blind, placebo-controlled randomized clinical trial with individuals with alcohol use disorder (AUD) seeking inpatient alcohol detoxification in the emergency department…
- Trial name
- NCT05661669
- Testing
- Ketamine, Saline
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Myocardial Oxygenation Imbalance, Myocardial Infarction
Clinical Presentation and Outcomes in Patients at Risk of Type II Myocardial InfarctioN in the emerGency Department.
Type 2 myocardial infarction has been reported in the Universal Definition of Myocardial Infarction for more than 10 years and most studies resulted in a high mortality rate.
- Trial name
- COMING (NCT03953651)
- Testing
- Follow-up
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Failure, Hypoxia
HVNI vs NIPPV in Type 2 Respiratory Failure
The purpose of this study is to determine if high velocity nasal insufflation (HVNI) is comparable to non-invasive positive pressure ventilation (NIPPV) in treatment of emergency patients with acute respiratory acidosis.
- Conditions
- Respiratory Failure, Hypoxia, Hypercapnia
- Trial name
- SHINE (NCT07065656)
- Testing
- Vapotherm high velocity therapy (HVT) 2.0 (Vapotherm, Inc, Exeter, NH), Respironics Vision V60
- Volunteers
- 84 people
- Sponsor
- National University Hospital, Singapore
Hypertension
Emergency Department Interventions to Improve Blood Pressure Follow-up
Hypertension affects approximately 65 million people in the United States and approximately 20 million individuals remain undiagnosed.
- Trial name
- NCT00798551
- Testing
- Risk counseling
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Nebraska
Frailty in Aging, Emergency Department Visit
Patient Experience of CFS-assessment in the ED
An increasingly common subject of interest among emergency care research is frailty, which is commonly described as a decline in several inter-related physiological systems, in addition to an increased vulnerability to stressors.
- Conditions
- Frailty in Aging, Emergency Department Visit, Patient Experience, Qualitative Research
- Trial name
- NCT06621290
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- University Hospital, Linkoeping
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Patient Education
Feasibility of a Standardized Video for Patient Education and as a Decision Aid on Code Status for Patients in the Emergency Department Pending Admission to the Hospital
The researchers hypothesize that patients and their families will be comfortable watching standardized CPR informational videos and that they would recommend that others watch the videos.
- Trial name
- NCT03213197
- Testing
- CPR video
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Hyperkalemia
Lower vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department
This clinical trial aims to evaluate the safety and efficacy of a lower dose insulin compared to the conventional dose for treating mild to moderate hyperkalemia, a condition characterized by elevated serum potassium levels below…
- Trial name
- IDK+ (NCT06724991)
- Testing
- Lower Dose Therapy, Conventional Dose Therapy
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Heart Disease, Myocardial Infarction
Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization
The PATCAR study has been designed to test the hypothesis that the strategy of pre-hospital use of a "clot busting" (thrombolytic) drug followed with emergent heart catheterization including stenting of the problematic coronary…
- Conditions
- Heart Disease, Myocardial Infarction, Acute Myocardial Infarction
- Trial name
- PATCAR (NCT00178620)
- Testing
- Reteplase 10 Units (U) plus a second dose of reteplase 10 U, Reteplase 10 U, Urgent Percutaneous Coronary Intervention (PCI)
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- The University of Texas Health Science Center, Houston
Sepsis, Disease Progression
Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department
To investigate the role of initial venous lactate in predicting the severity progression to overt septic shock and 30-day mortality in non-elderly patients without hemodynamic shock who suspected to have acute infections.
- Conditions
- Sepsis, Disease Progression, Septic Shock, Fatal Outcome
- Trial name
- NCT01947127
- Where
- Thailand
- Volunteers
- 458 people
- Sponsor
- Chulalongkorn University
Cancer, Emergencies
Efficacy of a Systematic Referral to Palliative Care of Patients Who Need for Palliative Care During an Unscheduled Visit in Comprehensive Anticancer Centers
This is a randomized, multicenter, prospective, phase III study conducted in daily emergency rooms of French Regional Comprehensive Cancer Centers.
- Trial name
- PALLU (NCT06150027)
- Testing
- Systematic referral to a palliative care team
- Where
- 6 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Leon Berard
Trauma
SWiFT Canada (Study of Whole Blood in Frontline Trauma)
Traumatic injuries affect people of all ages, races, and socioeconomic backgrounds. The Global Burden of Disease study showed that globally in 2019, there were more than 4.4 million deaths due to injury.
- Trial name
- SWiFTCanada (NCT06495294)
- Testing
- Whole Blood, RBC + plasma
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Primary Health Care
Impact of a Community-Based Primary Health Care Project on the Inappropriate Use of Emergency Medical System in Bergamo
The goal of this study is to reduce the inappropriate use of the Emergency Medical System in Bergamo. The main question it aims to answer is: can a Community-Based Primary Health Care Project impact on the use of the Emergency…
- Trial name
- PHC-BG_EMS (NCT06862882)
- Testing
- Community-Based Primary Health Care
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione San Giuliano Onlus
Asthmatic Patients, MDI
Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI.
- Conditions
- Asthmatic Patients, MDI, Aerosol Generating Procedure
- Trial name
- NCT06816342
- Testing
- Ventoline® Evohaler® 100 µg/inhalation pMDI alone, Ventoline® Evohaler® 100 µg/inhalation pMDI connected to Able spacer, Ventoline® Evohaler® 100 µg/inhalation pMDI connectec to Tips-Haler spacer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Suicide
Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE)
The NIMH s RFA-Suicide Prevention in Emergency Medicine Departments recognizes the emergency department (ED) as an important setting to increase suicide detection and prevention efforts but observes that evidence-based practice…
- Trial name
- ED-SAFE (NCT01150994)
- Testing
- Safety Assessment and Follow-up Telephone Intervention (SAFTI).
- Where
- 8 sites in United States
- Volunteers
- 1,440 people
- Sponsor
- University of Massachusetts, Worcester
Heart Failure
Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Disease Alone
This study will be conducted in subjects with clinical diagnosis of worsening chronic heart failure and either type 2 diabetes mellitus (DM) with or without chronic kidney disease (CKD) or moderate CKD alone treated with…
- Trial name
- ARTS-HF Japan (NCT01955694)
- Testing
- BAY94-8862, Eplerenone
- Where
- 29 sites in Japan
- Volunteers
- 72 people
- Sponsor
- Bayer
Bronchiolitis
Evaluation of Short Enteral Nutrition in the Emergency Room for Bronchiolitis With Main Nutritional Impairment
The winter epidemic of bronchiolitis in infants poses insurmountable difficulties for the hospital system for the 2022-2023 season globally.
- Trial name
- 1TreSBCD (NCT06304727)
- Testing
- clinical data review
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon