Clinical trials: Emergency Department Patients
Acute Gastrointestinal Bleeding
Point-of-care Ultrasound Interest in Acute Gastrointestinal Bleeding Emergency Department Patients
Acute Gastrointestinal (GI) Bleeding are a common chief complaint among Emergency Department. The mortality rate for Lower GI Bleeding is 3.9%. While the mortality rate can be as high as 10% for Upper GI Bleeding.
- Trial name
- NCT04436575
- Testing
- Point-of-care ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- SUD Association pour le Développement de la Recherche et de lEnseignement
Violence Against Women (VAW)
Feasibility of Systematic Domestic Violence Screening Using WAST in the Villefranche/Saône Emergency Department.
This single-center observational study aims to assess the feasibility of systematically screening for intimate partner violence (IPV) against women in the emergency department of Hôpital Nord-Ouest de Villefranche-sur-Saône.
- Trial name
- FdsVC-WAST-u (NCT07827534)
- Testing
- Self-questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- L'hôpital Nord-Ouest - Villefranche Villefranche sur Saône
Acute Exacerbation of COPD, Lung Diseases
Antibiotic Stewardship in AECOPD Through CRP-Guided Management
Objectives: To determine whether CRP-guided antibiotic treatment for managing AECOPD in adult patients attending Emergency Departments leads to reduced antibiotic duration, without non-inferior COPD health status with usual care.
- Conditions
- Acute Exacerbation of COPD, Lung Diseases, Lung Diseases, Obstructive, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05286918
- Testing
- The intervention (CRP-guided) group
- Where
- Hong Kong
- Volunteers
- 1,184 people
- Sponsor
- The University of Hong Kong
Pulmonary Embolism
Prevalence of Pulmonary Embolism in Patients With Dyspnea on Exertion (PEDIS)
PEDIS Study is an observational, cross-sectional, multicenter Italian study conducted in a consecutive series of patients who refer to the Emergency Departments (either spontaneously or sent by their attending physicians) for the…
- Trial name
- PEDIS (NCT04454554)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Arianna Anticoagulazione Foundation
COVID-19
Emergency Ventilator Splitting Between Two or More Patients (COVID-19)
The purpose of this study is to develop a safe, easily scalable, and simple method to split a single ventilator for use amongst two or more patients, thus serving as a capacity bridge to save patient lives until manufacturers can…
- Trial name
- NCT04381013
- Testing
- Emergency Ventilator Splitter
- Where
- United States
- Sponsor
- Stanford University
Pain, Acute
Effect of Vitamin C on Pain Reduction After an Emergency Department Visit
Musculoskeletal (MSK) injuries such as sprains, strains, bruises, and fractures are among the most common reasons people visit the emergency department.
- Trial name
- Vicamed (NCT06306183)
- Testing
- Vitamin C
- Where
- 4 sites in Canada
- Volunteers
- 204 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Advanced Chronic Disease
Study of the Care Pathway of Patients Admitted to the Palliative Care Unit of Strasbourg University Hospital From Their Home in 2025
Palliative care aims to improve the quality of life of patients with life-threatening illnesses and their families through early identification, assessment, and management of physical, psychosocial, and spiritual needs.
- Trial name
- PHSDD (NCT07858760)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Ebola Virus Disease
Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola)
The purpose of this study is to evaluate the efficacy and safety of amiodarone in the treatment of patients afflicted with Ebola virus disease.
- Trial name
- EASE (NCT02307591)
- Testing
- Best Supportive Care, Best Supportive Care + Amiodarone
- Sponsor
- Emergency NGO Onlus
Asthma
Evaluation of the Written Information Delivered by the General Practitioner of the Patients Presenting to the Emergency Room for an Aggravation of Asthma
Asthma is a common pathology (prevalence 6.4% in 2018, in France), currently managed by the general practitioner in general practice. It is a chronic disease at risk of exacerbation, which can lead to the use of care.
- Trial name
- ASTHMAVILLE (NCT04048746)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Asthma Exacerbation, Emergency Department
Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED
The goal of this clinical is to compare treatment outcomes between high dose continuous IV Magnesium and standard therapy in the management of acute exacerbation of asthma in the emergency department.
- Conditions
- Asthma Exacerbation, Emergency Department, Magnesuim Sulfate, High Dose
- Trial name
- HIMAG-ED-STAT (NCT07795970)
- Testing
- ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Heart Failure
Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED)…
- Trial name
- NCT06065761
- Testing
- Comprehensive ED heart failure management tool
- Where
- 21 sites in United States
- Volunteers
- 17,459 people
- Sponsor
- Kaiser Permanente
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Opioid Dependence
Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments
This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients.
- Trial name
- NCT02586896
- Testing
- Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
Medication Reconciliation, Emergency Department
Medication Histories Conducted by Nurses (RNs), Pharmacy Techs (CPhTs) & Pharmacists (RPhs)
Up to 50% of medication errors and 20% of adverse drug reactions (ADRs) in the hospital setting are estimated to be related to communication issues regarding patient medications at various transition points of care from admission…
- Trial name
- NCT01065675
- Testing
- Medication reconciliation completed by a RN, CPhT, or RPh
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Wesley Medical Center
Fever, Respiratory Tract Infections
Diagnostic Accuracy of a Host-response Based Diagnostic Tool for Distinguishing Between Bacterial and Viral Etiologies in Pediatric Patients
This is a prospective clinical validation study of a novel regulatory approved (CE-IVD) diagnostic assay called ImmunoXpert™ that will enroll 1222 pediatric patients.
- Trial name
- AutoPilot (NCT03052088)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 1,140 people
- Sponsor
- MeMed Diagnostics Ltd.
Ankle Sprains
Evaluation of the Recovery Experienced by Patients After an Ankle Sprain Treated in the Emergency Department of Nantes University Hospital
To evaluate the recovery experienced by patients with ankle sprains treated in the adult emergency department of Nantes University Hospital.
- Trial name
- ANKHEAL (NCT06657937)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Nantes University Hospital
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Weight-Estimation
Can Habitus Adapted Length Based Body Weight Estimation be Improved by Adding Further Parameters?
The purpose of this prospective single center study is to investigate if the accuracy of length based body weight estimation by the already investigated algorithm (CLAWAR) can be improved by adding another parameter.
- Trial name
- Including MUC (NCT02930928)
- Testing
- Accuracy of weight estimation
- Where
- Switzerland
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Emergency Laparotomy, Intestinal Obstruction
Enhanced Recovery Versus Standard Care After Emergency Abdominal Surgery in Patients Requiring Emergency Laparotomy
This study aims to compare an Enhanced Recovery After Surgery (ERAS) protocol with conventional postoperative care in adults undergoing emergency laparotomy for intestinal obstruction or intestinal perforation.
- Conditions
- Emergency Laparotomy, Intestinal Obstruction, Intestinal Perforation, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT07650461
- Testing
- Enhanced Recovery After Surgery, Conventional Postoperative Care
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh