Clinical trials: Emergency Department Presentation
Homeless Persons, Emergency Medical Services
Attitudes of Medical Trainees Towards Homeless Persons Presenting for Care in the Emergency Department
Homelessness is a significant problem in Canada, and many homeless people will seek routine care in the Emergency Department (ED) as a result of barriers to access.
- Trial name
- NCT00281398
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Anemia
Phenotyping Acute Non-Severe Anemia in the Emergency Department
Anemia is traditionally diagnosed and managed using circulating hemoglobin concentration ([Hb]). However, [Hb] is influenced by plasma volume and may not accurately reflect the total amount of hemoglobin available for oxygen…
- Trial name
- PHENOEMEMIA (NCT07761104)
- Testing
- Total hemoglobin mass measurement, Focused transthoracic echocardiography, Near-infrared spectroscopy
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Delirium
Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program
Delirium occurs in up to 20% of older adults presenting to the Emergency Department (ED) and is associated with poor outcomes. Failure to identify patients with ED delirium not only prevents initiation of mitigation strategies…
- Trial name
- ED-DDP (NCT05606328)
- Testing
- Emergency Department Delirium Screening and Detection Program (ED-DDP)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Falls (Accidents) in Old Age, Falls
Evaluation of the Relationship Between Fall Risk, Muscle Strength, and Anticholinergic Burden in Geriatric Patients Presenting to the Emergency Department
Falls are common among older adults and can lead to serious injury. This study looks at whether taking many medications (polypharmacy), the anticholinergic burden of those medications (a measure of side effects that can affect…
- Conditions
- Falls (Accidents) in Old Age, Falls, Anticholinergics, Sarcopenia
- Trial name
- NCT07813143
- Where
- Turkey (Türkiye)
- Volunteers
- 333 people
- Sponsor
- Gazi University
Acute Coronary Syndrome
Rapid Assessment of Potential Ischaemic Heart Disease With CTCA
This study aims to investigate the effect of early CTCA in patients with suspected or confirmed Acute Coronary Syndrome (ACS) presenting to the Emergency Department (ED) or Medical Assessment Unit (MAU), upon interventions, event…
- Trial name
- RAPID-CTCA (NCT02284191)
- Testing
- CT Coronary Angiogram
- Where
- 37 sites in Jersey, United Kingdom
- Volunteers
- 1,749 people
- Sponsor
- University of Edinburgh
HIV Infections, Syphilis Infection
Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department
The purpose of this study is to evaluate infection detection and treatment initiation rates for syphilis and HIV before and after integration of the Chembio DPP® HIV-Syphilis rapid POC test into an ongoing Emergency Department…
- Trial name
- NCT07525076
- Testing
- Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Pain Due to Trauma
Efficacy and Safety of Methoxyflurane (Penthrox) for the Treatment of Acute Pain in Minor Trauma
This study investigates the treatment of acute pain, an unpleasant feeling caused by an injury. The overall purpose of the study is to gain more information that the pain relief medicine Penthrox(Methoxyflurane) administered…
- Trial name
- STOP! (NCT01420159)
- Testing
- Methoxyflurane
- Where
- 6 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Medical Developments International Limited
Pain
A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain
RESEARCH QUESTION: In adult ED patients in whom the attending ED physician has decided to administer intravenous opiates, what is the difference in pain relief at 60 minutes in patients who are randomized to receive either…
- Trial name
- NCT00293969
- Testing
- Morphine 0.1mg/kg versus morphine 0.15 mg/kg
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Montefiore Medical Center
Acute Kidney Injury, Urinary Tract Obstruction
Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department
Acute kidney injury (AKI) is a common diagnosis in the emergency department (ED), and urinary tract obstruction is a contributing cause that requires rapid diagnosis and therapeutic management.
- Trial name
- NCT06040736
- Where
- France
- Volunteers
- 155 people
- Sponsor
- University Hospital, Montpellier
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed
Durham Connects RCT Evaluation II
The aim of this randomized controlled trial (RCT) is to conduct a second, independent evaluation the implementation and impact of the Durham Connects (DC) brief universal nurse home-visiting program to prevent child maltreatment…
- Trial name
- NCT01843036
- Testing
- Durham Connects
- Where
- United States
- Volunteers
- 1,650 people
- Sponsor
- Duke University
COVID-19, Inflammatory Response
Severe COVID-19 Infection in Children Presenting to EDs in Israel and England
Even though the COVID-19 pandemic is no longer at its peak, the threat still lingers. Engaging in prospective surveillance studies will enable us to monitor the disease and prepare for any potential resurgence.
- Trial name
- SPICE (NCT06434701)
- Testing
- Nasopharyngeal swab sampling for COVID-19
- Where
- 6 sites in Israel
- Volunteers
- 500 people
- Sponsor
- Hadassah Medical Organization
Snake Bite
Predictive Accuracy of the Snakebite Severity Score (SSS) in Identifying Syndrome-Specific Core Outcome Parameters Among Envenomated Patients Presenting to the Emergency Department
India reports ~58,000 snakebite deaths/year, over 50% of global mortality. Clinical outcomes of antivenom may vary due to regional venom differences, delayed access to care, ineffective use of existing polyvalent antivenom.
- Trial name
- SCOPE-Snake (NCT07079137)
- Testing
- History, examination, bite documentation, SSS scoring,Baseline labs as per institutional protocol
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Ankle Sprain
Ketoprofen Gel vs Placebo in Children With Ankle Sprain
The aim of this study is to analyse the effect of ketoprofen gel in children presented with ankle sprain to the emergency department.
- Trial name
- NCT02491736
- Testing
- Ketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University
Pain, Acute
Methoxyflurane Analgesia for Paediatric Injuries
This is a randomised, double-blind, multicentre, placebo controlled study to evaluate the safety and efficacy of methoxyflurane (Penthrox®) for the treatment of acute pain in children and adolescents from 6 to less than 18 years…
- Trial name
- MAGPIE (NCT03215056)
- Testing
- Methoxyflurane, Normal saline
- Where
- 11 sites in Ireland, United Kingdom
- Volunteers
- 192 people
- Sponsor
- Medical Developments International Limited
Chest Pain
Impact on Management of the HEART Risk Score in Chest Pain Patients
Aim of this study is to quantify the impact of the use of the HEART risk score on patient outcome and on costs in patients with chest pain presenting at the emergency room, as compared to not using the score.
- Trial name
- HEART-Impact (NCT01756846)
- Testing
- usual care, use of HEART risk score
- Where
- 9 sites in Netherlands
- Volunteers
- 3,666 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Colorectal Cancer
Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal Snapshot
APOLLO (Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal snapshot) is an international, multi-centre, prospective observational study which will address this need and aims to describe the operative and non-operative…
- Trial name
- APOLLO (NCT05641129)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- European Student Research Network
Traumatic Brain Injury, Acute Respiratory Failure
Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain Injury
Despite almost universal usage of supplemental oxygen therapy in patients presenting in the emergency department with traumatic brain injury (TBI), optimal oxygen levels are unclear.
- Conditions
- Traumatic Brain Injury, Acute Respiratory Failure, Acute Respiratory Distress Syndrome, Acute Brain Injury
- Trial name
- INACHOS (NCT05464277)
- Testing
- Oxygen
- Where
- 2 sites in Greece
- Volunteers
- 1 people
- Sponsor
- Evangelismos Hospital
Atmospheric Pressure; Adverse Effect, Epistaxis Nosebleed
Atmospheric Pressure and Epistaxis Relationship
In this study, investigators aim to understand the relationship between changes in atmospheric pressure and blood pressure, and to investigate whether these changes have an impact on the etiology of epistaxis.
- Trial name
- NCT06531577
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Saglik Bilimleri Universitesi
Infection
NEWS2+Procalcitonin Association in Patients With Infection and Its Significance in Oncological Patients
This observational study aims to evaluate the prognostic significance of the combination of a clinical score (specifically, a score obtained through the measurement of multiple parameters such as blood pressure, body temperature…
- Trial name
- NCT06761118
- Where
- Italy
- Volunteers
- 1,041 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hyponatremia
Analysis of the Epidemiology, Clinical Presentation and Therapy as Well as Therapy-associated Risk of Demyelination Syndrome in Patients With Profound Hyponatremia in the Emergency Department
Hyponatremia is a frequent cause for presentation to the emergency department (ED). While patients with chronic hyponatremia often exhibit minor symptoms, acute development of hyponatremia can lead to global cerebral edema…
- Trial name
- ProfHN_in_ZNA (NCT06781710)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University of Cologne