Clinical trials: Emergency Departments
Emergency
Measurement of Care Safety Culture in French ICU, Correlation With the Characteristics of Morbi-mortality Reviews
The tools to measure safety culture (CS) have recently become available. No study has focused on the measure in France, apart from pilot studies.
- Trial name
- REA-C-SUR (NCT02880826)
- Testing
- Measure the culture of safety in the reanimation units
- Where
- France
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Substance Use
Brief Intervention and Referral to Treatment With Substance Use Disorders in the Emergency Room Setting
This study will be a quality improvement project to review the effectiveness and barriers to effectiveness of a new clinical program in the emergency room to provide substance use screening followed by brief motivational…
- Trial name
- NCT01661517
- Testing
- Motivational interviewing and referral to treatment
- Where
- United States
- Volunteers
- 5,271 people
- Sponsor
- University of Alabama at Birmingham
Drug Monitoring, Anticoagulants
Plasma Concentration Monitoring of Direct Oral Anticoagulants in Emergency Department Patients: Comparison of Two Laboratory Methods
The goal of this observational study is to learn whether two laboratory tests give the same results when measuring blood levels of blood thinners.
- Conditions
- Drug Monitoring, Anticoagulants, Factor Xa Inhibitors, Direct Oral Anticoagulants (DOACs)
- Trial name
- Plasma Concent (NCT07917455)
- Where
- 2 sites in Italy
- Volunteers
- 142 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Multiple Organ Failure
LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting
The purpose of this study is evaluate if K3, a novel biomarker, sampled at arrival to the emergency department can be used to predict the development of organ failure measured as SOFA score.
- Trial name
- NCT01937676
- Where
- Sweden
- Volunteers
- 1,250 people
- Sponsor
- Karolinska Institutet
Severe Infection, Sepsis
Evaluation of MDW for Early Detection of Sepsis, Clinical Validity
The purpose of this study is to confirm the clinical validity and the performance of the Monocyte Width Distribution (MDW) parameter to detect the development of sepsis in a prospective study of Emergency Department (ED) adults…
- Conditions
- Severe Infection, Sepsis, Severe Sepsis
- Trial name
- NCT03588325
- Testing
- CBC-DIFF with MDW, PCT, CRP
- Where
- 2 sites in France, Spain
- Volunteers
- 947 people
- Sponsor
- Beckman Coulter, Inc.
Sepsis
Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients
This is an investigator-initiated, multicenter, randomized, parallel-group, open-labeled, feasibility trial investigating volumes of fluid within 24 hours in 124 patients with sepsis allocated to two different IV fluid regimens…
- Trial name
- REFACED Sepsis (NCT05076435)
- Testing
- Isotonic crystalloids
- Where
- 3 sites in Denmark
- Volunteers
- 124 people
- Sponsor
- Marie Kristine Jessen, MD
Infection, Precancerous/Nonmalignant Condition
Emergency Use of Adoptive Immunotherapy With CMV-Specific T Cells After Donor Bone Marrow Transplant of an Infant With Immunodeficiency Syndrome and CMV Infection
RATIONALE: Collecting the T cells from a donor and transplanting them into a patient may be effective treatment for immunodeficiency syndrome and CMV infection.
- Trial name
- NCT00547235
- Testing
- therapeutic allogeneic lymphocytes, allogeneic bone marrow transplantation, total-body irradiation
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Cesarean Delivery
Anesthesia and Neonatal Outcomes After Cesarean Delivery
This retrospective observational study examines the association between the type of anesthesia used during cesarean delivery and early neonatal outcomes.
- Trial name
- NCT07893808
- Testing
- General Anesthesia (GA), Neuraxial Anesthesia (NA)
- Where
- Turkey (Türkiye)
- Volunteers
- 21,926 people
- Sponsor
- Serra Topal
Atrial Fibrillation
A.Fib Emergency Department Study Atrial Fibrillation
Patients with a history of atrial fibrillation (AF) who frequently attend the emergency department (ED) with symptoms may not require emergency treatment, and may be more appropriately managed in an alternative outpatient…
- Trial name
- NCT03127085
- Where
- Canada
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Queen's University
Dyspnea
Evaluation of the Impact of Pleuropulmonary Ultrasound on the Diagnosis of Dyspnea
Dyspnea is a subjective symptom perceived by the patient as a sensation of "breathing discomfort", "suffocation", "lack of air" or "difficulty inhaling or exhaling". It is a frequent reason for calling for help (8% of calls).
- Trial name
- LU-SMUR (NCT07104578)
- Testing
- Pleuropulmonary ultra sound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Small Bowel Obstruction, Frailty
The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery.
- Conditions
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- Trial name
- NGTUBE-OBS (NCT06262815)
- Testing
- Nasogastric tube placement, Clinical Frailty Scale
- Where
- 8 sites in Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Daniel Wilhelms
Acute Stress Disorder, Anxiety
Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room
The hypothesis is that intranasal dexmedetomidine will provide significantly more effective analgesia and anxiolysis for subjects undergoing a simple laceration repair when compared to either intranasal fentanyl or intranasal…
- Conditions
- Acute Stress Disorder, Anxiety, Pain
- Trial name
- NCT05057689
- Testing
- Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Sleep Disorder (Disorder)
The Correlation Between Sleep Quality and Sleep Aid Use and Dietary Patterns
In this study, medical staff in emergency and critical care departments were investigated. It was assumed that the use of sleep aids and dietary patterns affected their sleep quality.
- Trial name
- NCT07019948
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Pulmonary Embolism
Electronic Support for Pulmonary Embolism Emergency Disposition
To evaluate the impact of an integrated electronic clinical decision support system to facilitate risk stratification and site-of-care decision-making for patients with acute pulmonary embolism.
- Trial name
- eSPEED (NCT03601676)
- Testing
- Integration of electronic clinical decision support
- Where
- 14 sites in United States
- Volunteers
- 1,703 people
- Sponsor
- Kaiser Permanente
Atrial Fibrillation
High Sensitivity Cardiac Troponin T in Patients With Atrial Fibrillation Admitted to an Emergency Department (ED)
The purpose of this study was to collect data on the prevalence and clinical significance of elevated cardiac troponin in a large registry of unselected patients with atrial fibrillation presenting to an emergency department.
- Trial name
- NCT02542189
- Volunteers
- 3,037 people
- Sponsor
- University Hospital Heidelberg
in Hospital Mortality, Geriatric
Prognosis of Geriatric Patients With Non-bedded Night in the Emergency Department: a Multicenter Cohort Study
Retrospective, multicenter, French cohort study. Data from patients over 75 years of age who visited the emergency department on 12 and 13 December 2022 could be collected until their discharge from hospital and for a maximum of…
- Trial name
- NoBedNight (NCT05821491)
- Where
- France
- Volunteers
- 1,598 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergency Laparotomy
Evaluation of Surgical Risk Prediction Tools.
Introduction: In modern surgery, the prediction of perioperative death gains significant importance due to the availability of treatment options, means of improving the surgical outcome and for proper patient information.
- Trial name
- NCT04615520
- Where
- Greece
- Volunteers
- 660 people
- Sponsor
- University Hospital of Crete
Case Management, Managed Care Program
San Francisco Health Plan Care Support Trial
This study will expand and evaluate an existing pilot program to improve care for frequent users of acute emergency and inpatient services by providing care coordination and management for eligible San Francisco Health Plan…
- Trial name
- SFHP_CBCM (NCT02463838)
- Testing
- Care Support Intervention
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- University of California, San Francisco
Acute Heart Failure
Early Aldosterone Blockade in Acute Heart Failure: An Exploratory Safety Study
Over one million hospitalizations for acute heart failure (AHF) occur over every year in the United States, resulting in high mortality, re-hospitalizations, and incurred financial costs; yet nearly every attempt over the last 10…
- Trial name
- NCT02299726
- Testing
- Spironolactone
- Sponsor
- Indiana University
Covid19, Emergencies
Prediction of the Patient Pathway in Emergency Room in an Exceptional Sanitary Situation
The COVID-19 outbreak leads to optimize the pathway in emergency departments. The length of time spent in the Emergency Department is linked to the morbi-mortality and the risk of COVID-19 transmission.
- Trial name
- 3PU-SSE (NCT04665778)
- Testing
- hospital bedroom booking
- Where
- France
- Volunteers
- 1,516 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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