Clinical trials: Emergency Departments
Respiratory Tract Infections
Point-of-care Testing of Respiratory Pathogens at Pediatric Emergency Room
The main objective of the trial is to evaluate the effect of point-of-care testing of respiratory pathogens at a pediatric emergency room on the antibiotic consumption and hospital admissions in acutely ill children.
- Trial name
- Hevi-RCT (NCT03932942)
- Testing
- QIAstat at pediatric emergency room
- Where
- Finland
- Volunteers
- 1,350 people
- Sponsor
- University of Oulu
Alcohol Drinking
ReDIAL: A Telephone Brief Intervention for Injured Emergency Department Patients
The goal of this study is to reduce impaired driving, risky driving and alcohol-related negative consequences among injured emergency department (ED) patients through a telephone brief intervention.
- Trial name
- ReDIAL (NCT01326169)
- Testing
- Brief intervention, Standard care
- Where
- 2 sites in United States
- Volunteers
- 730 people
- Sponsor
- Rhode Island Hospital
Elderly Patients Visiting the Emergency Department
Impact on Mid-term Mortality of Guidelines for ICU Admission of Elderly Patients Arriving in Emergency Departments
Admitting a very elderly patient to the Intensive Care Unit (ICU) is one of the most difficult clinical challenges in medicine. There are few data to help guide clinicians in this area: estimates of the benefits of ICU admission…
- Trial name
- ICECUBII (NCT01508819)
- Testing
- recommendations to admit to ICU all the patients included
- Where
- France
- Volunteers
- 3,036 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Consumption
Pilot Study of a Computer-Based Intervention for Alcohol Misuse in the Emergency Department
Alcohol misuse amongst youth is a significant clinical and public health problem. The Emergency Department (ED) is an important setting for the treatment of alcohol-related problems as it is often the first point of contact…
- Trial name
- NCT01146665
- Testing
- Computer-based PAF
- Where
- 3 sites in Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Community-Acquired Pneumonia, Fraility
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on…
- Conditions
- Community-Acquired Pneumonia, Fraility, Hospitalizations
- Trial name
- NCT07442656
- Testing
- Clinical frailty scale, Clinical Frailty Scale (CFS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Low Back Pain
Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs
Acute low back pain is the fifth most common presenting complaint to the emergency department, accounting for approximately 4.4% of annual visits.
- Trial name
- NCT04129437
- Testing
- Ibuprofen, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Hypertensive Emergency
The Value of TOI in Evaluating Renal Function Damage in Hypertensive Emergency Patients
TOI was used to measure heart rate, respiration, blood pressure, heart rate variability and psychological stress. At the same time, the patient's urine protein, creatinine, urea nitrogen and other indicators were detected.
- Trial name
- NCT06201572
- Testing
- The relationship between TOI composite index and renal function in hypertensive emergency patients was compared
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Surgical Site Infection (SSI)
Rationale of Subcutaneous Levofloxacin Infiltration as an Adjunct for Surgical Site Infection Prevention in Emergency Laparotomy
Surgical site infection (SSI) remains a major cause of postoperative morbidity following emergency laparotomy, particularly in contaminated and dirty/infected abdominal conditions.
- Trial name
- NCT07696819
- Testing
- Levofloxacin
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Sylhet M.A.G.Osmani Medical College
Trauma
Capillary Lactate and Transfusion Needs
13% of injured normotensive patients arriving in emergency unit need mass blood-transfusion of six or more units of packed Red Blood Cells. It is currently difficult to predict the need for such a mass blood-transfusion.
- Trial name
- NCT01793428
- Testing
- Capillary lactate level
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Grenoble
Surgery, Anesthesia
Surgical Capacity in Zimbabwean Public Hospitals
This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such…
- Trial name
- NCT06358183
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 80 people
- Sponsor
- Parirenyatwa Hospital
Trauma and Emergency Care
Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a clinical phenomenon caused by the abrupt rupture and bleeding of blood vessels at the surface or base of the brain, which can occur for a number of reasons.
- Trial name
- NCT07252505
- Testing
- Magnesium Sulfate 10 MG/ML
- Volunteers
- 50 people
- Sponsor
- Assiut University
Emergency Care, Clinical Decision Support
Artificial Intelligence(AI) in the Emergency Department (ED) in Cologne
This retrospective, non-interventional study evaluates the prognostic performance of open-weight Large Language Models (LLMs) in the setting of a German academic emergency department.
- Conditions
- Emergency Care, Clinical Decision Support, Triage
- Trial name
- KINA-CO (NCT07725965)
- Where
- Germany
- Volunteers
- 100,000 people
- Sponsor
- University of Cologne
Forearm Fracture, Ultrasound
Trial of Ultrasound Guidance for Reduction of Pediatric Forearm Fractures
The primary objective of this study is to assess the utility of ultrasound guidance in the closed reduction of pediatric forearm fractures in the pediatric emergency department.
- Trial name
- NCT03097757
- Testing
- Ultrasound - guided fracture reduction, Standard of care fracture reduction
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Myocardial Oxygenation Imbalance, Myocardial Infarction
Clinical Presentation and Outcomes in Patients at Risk of Type II Myocardial InfarctioN in the emerGency Department.
Type 2 myocardial infarction has been reported in the Universal Definition of Myocardial Infarction for more than 10 years and most studies resulted in a high mortality rate.
- Trial name
- COMING (NCT03953651)
- Testing
- Follow-up
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Hospices Civils de Lyon
Disaster Planning, Emergency Medical Services
The KAEPacity Study Analyzes Hospital Emergency and Disaster Plans From Hospitals Across Germany to Evaluate How Well Hospitals Are Prepared for Crises and Disasters Organizational Structures Communication Leadership Training Are Examined Within These Plans No Medical Intervention is Performed
Hospital Emergency and Disaster Plans (Krankenhausalarm- und Einsatzplan-KAEP) are a central component of hospital preparedness in Germany.
- Conditions
- Disaster Planning, Emergency Medical Services, Germany
- Trial name
- KAEPacity (NCT07440329)
- Where
- Germany
- Volunteers
- 319 people
- Sponsor
- Lea Kölsch
Pulmonary Complication, Cardiovascular Complication
Perioperative Pulmonary Monitoring in Major Emergency Surgery
1. Describe the incidence of postoperative hypoxemia after major emergency abdominal surgery as well as correlate this to clinical outcomes. 2.
- Conditions
- Pulmonary Complication, Cardiovascular Complication, Postoperative Complications
- Trial name
- PROMIES (NCT03977337)
- Testing
- Major emergency abdominal surgery
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Zealand University Hospital
Hiv, Nurse's Role
Does the Implementation of Nurse-driven HIV Screening for Key Populations in the Emergency Departments Limit Undiagnosed Infections in the Paris Metropolitan Area? DEPIST Trial (ANRS 14055)
In France, 40% of newly diagnosed HIV infections are concentrated in the Paris metropolitan area. Two key populations are mainly concerned: persons born in a foreign country and men who have sex with men.
- Trial name
- DEPIST (NCT04298801)
- Testing
- Nurse-driven HIV screening for key populations combined with usual physician-directed diagnostic testing, Physician-directed diagnostic testing
- Volunteers
- 487,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Joint Dislocation, Limb Fracture
Target-controlled Infusion With Propofol in the Emergency Department : a Prospective Study on 45 Adult Patients
Procedural sedation is an emergency medicine technique that provides a brief, deep sedation in order to perform very painful emergency emergent procedures such as displaced fracture or dislocated joints reduction.
- Trial name
- SIVOC (NCT03783494)
- Testing
- Target control infusion with propofol
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Injury Prevention
Brief Child Safety Interventions in Emergency Departments (Safety in Seconds)
Safety in seconds is a randomized controlled trial of a computer tailored Injury Prevention program which was conducted in the waiting area of a level 1 pediatric trauma center.
- Trial name
- NCT01432041
- Testing
- tailored health education
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Caregiver Participation, Emergency Department Presentation
Supporting Caregivers Following Mental Health Emergency Department Visits
The investigators plan to conduct a pilot hybrid effectiveness-implementation type 1 randomized controlled trial comparing 3 arms of varying follow-up intervention.
- Conditions
- Caregiver Participation, Emergency Department Presentation, Safety Plan
- Trial name
- SCFMHEDV (NCT07411300)
- Testing
- Telephone Calls, Automatic MyChart Messages
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
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