Clinical trials: Emergency Departments
Cardiac Arrest
Effects of Laryngeal Tube Ventilation on no Flow Time During Out of Hospital Cardiac Arrest
International recommendations stress on the importance of no flow time reduction in cardiac arrest management. In fact, no flow time is an independent factor of morbidity and mortality.
- Trial name
- FLOWERS (NCT01295749)
- Testing
- laryngeal tube ventilation and continuous chest compression
- Where
- 2 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Grenoble
Bariatric Surgery, Postoperative Complications
National Emergency Bariatric Surgery Audit
The goal of this observational study is to investigate the incidence, management, and outcomes of complications following bariatric surgery in patients in the United Kingdom.
- Conditions
- Bariatric Surgery, Postoperative Complications, Emergencies, Surgical Procedures, Operative
- Trial name
- NEBSA (NCT06738004)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Bedfordshire Hospitals NHS Foundation Trust
Pain
Pediatric Ketamine Study for Pain Management
Direct comparison of intranasal sub-dissociative dose ketamine with intranasal fentanyl for the treatment of moderate to severe pain in pediatric patients in the emergency department.
- Trial name
- NCT02388321
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Antonios Likourezos
Alcoholic Intoxication, Wounds and Injuries
Phone Intervention for Alcohol (ETOH) Use in Emergency Department Motor Vehicle Crash (ED MVC) Patients
The purpose of this study is to determine if a brief counseling intervention, delivered by telephone, is more effective than standard ED care, to reduce future alcohol related injuries and alcohol related negative consequences…
- Trial name
- DIAL (NCT00457548)
- Testing
- Brief Telephone Counseling for risky aclohol use
- Sponsor
- Rhode Island Hospital
Pancreatic Cancer
Compassionate Single Subject Use of FG-3019 (FibroGen) in Locally Advanced, Unresectable Pancreatic Cancer
Single compassionate use subject is an 83 year old woman with a history of lymph node positive breast cancer and recently diagnosed pancreatic cancer in May.
- Trial name
- NCT02851381
- Testing
- FG-3019
- Sponsor
- Jonsson Comprehensive Cancer Center
Acute Pain
Electronic Defaults to Reduce Opioid Prescribing in Emergency Department and Primary Care Settings
The goal of this research is to investigate the impact of changing opioid analgesic prescribing defaults on the quantity of opioids prescribed for acute non-cancer pain in adult primary care and emergency department settings.
- Trial name
- NCT03003832
- Testing
- Change in electronic health record default for new opioid analgesic prescriptions
- Volunteers
- 15,000 people
- Sponsor
- Montefiore Medical Center
Mortality, Pediatric
Operative Duration as a Predictor of Mortality in Pediatric Emergency Surgery
Introduction Operative duration is an important but under-studied predictor of mortality in emergency laparotomies. Aims \& Objectives The objective of this study was to quantify the effect of duration of emergency laparotomy in…
- Conditions
- Mortality, Pediatric, Laparotomy, Emergencies
- Trial name
- NCT03270930
- Testing
- Emergency laparotomy
- Volunteers
- 213 people
- Sponsor
- Jawaharlal Nehru Medical College
Genital Human Papilloma Virus Infection
A Model for Implementation of Cervical Cancer Screening and HPV Vaccination the Emergency Department: a Pilot Study
In this pilot study, we intend to demonstrate that a great portion of women at high risk (inadequate screening, HPV 16/18 and/or cytology) are presenting to the ED, cytology/ HPV testing via ThinPrep®Pap testTM and surveillance.
- Trial name
- NCT01133509
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Traffic Collision, Transport Accident
Causes of Traffic Collisions of Ambulance Cars at the Prague Emergency Medical Services
The aim of the project is to increase the protection of patients, employees and the organization by means of data collection about traffic collisions of ambulance cars.
- Trial name
- NCT04808219
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Peran
Surgical Wound
Comparison of Interrupted Suturing Versus Continuous Suturing in Laparotomy Wound Closed.
Emergency laparotomy is associated with high morbidity, particularly due to wound dehiscence and infection. Choosing an optimal suturing technique can significantly impact patient outcomes, but data on the comparison of…
- Trial name
- NCT07601919
- Testing
- Interrupted Closure, Continuous Closure
- Where
- Pakistan
- Volunteers
- 184 people
- Sponsor
- Muhammad Aamir Latif
Infant Safe Sleep Practices, SIDS
Infant Safe Sleep in Pediatric Emergency Depratment
Safe sleep recommendations from the American Academy of Pediatrics (AAP) are designed to reduce the risk of sudden infant death syndrome (SIDS) and other sleep-related infant deaths.
- Trial name
- NCT07779512
- Testing
- Safe Sleep Education, Behavior habit tracking
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- State University of New York at Buffalo
Substance Use
Routine Clinical Screening for Substance Use Disorders in the Emergency Room Setting
To ensure consistent documentation of alcohol and substance use, the emergency medicine is initiating a new standard of care for substance use screening: the use of a brief self-evaluation questionnaire on alcohol, tobacco and…
- Trial name
- NCT01661465
- Where
- United States
- Volunteers
- 9,212 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Benign Paroxysmal Positional Vertigo
Effect of a Multifaceted Educational Intervention on the Implementation of Evidence-based Practices for Benign Paroxysmal Positional Vertigo in an Emergency Department
Acute vertigo accounts for around 4% of emergency room visits. Triggered episodic vestibular syndrome is the most commonly encountered symptomatic context.
- Trial name
- BPPV-Teaching (NCT06314581)
- Where
- France
- Volunteers
- 382 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pain Management
Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients
The goal of this pilot randomized clinical trial is to learn if oral ketamine intervention can control pain in emergency department patients whose providers feel the need for additional pain medication.
- Trial name
- PKORCT (NCT07670507)
- Testing
- oral ketamine, oxycodone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Albany Medical College
Chronic Postoperative Pain
Persistent Postoperative Pain After Major Emergency Abdominal Surgery
Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake…
- Trial name
- NCT04508465
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Zealand University Hospital
Dermatological Emergency
Application of Telemedicine for Dermatological Emergency Patients
After admission to the emergency room each dermatological patient is routinely assessed to Manchester Triage System (MTS) by the nursing staff.
- Trial name
- Telederm (NCT02836665)
- Testing
- Telemedicine for dermatological emergency patients
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Vertigo, Peripheral, Vertigo, Brain Stem
Copeptin and the S-100b Protein in Stroke
This study evaluated the value of using copetin and protein S 100 b to eliminate the diagnosis of stroke in patients presenting with vertigo in emergency departments.
- Conditions
- Vertigo, Peripheral, Vertigo, Brain Stem, Vertigo; Central, Vertigo; Cerebral
- Trial name
- NCT03974464
- Testing
- copeptin, PS100
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Dementia, Caregiver
ED PLWD/Care Partner Text Messaging
The purpose of this research study is to develop and test a text-messaging intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Mobile Health Technology (mHealth)
- Trial name
- CAPTURE (NCT07423871)
- Testing
- CAPTURE Text Message Care Transition Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome
Paediatric Syncope in the Emergency Department
The investigators will assess the efficacy of clinically recommended counterpressure maneuvers (CPM) in preventing syncope for paediatric patients.
- Conditions
- Syncope, Vasovagal, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- DETECT-ED (NCT05555771)
- Testing
- Counterpressure Maneuvers, Usual Care
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Dr. Victoria Claydon
Metabolic Syndrome
The Pick Two to Stick To Habit Development Intervention
Metabolic syndrome (MetS) is a leading risk factor for chronic disease among African American/Black populations. Fostering habit development offers a promising new approach to improving the effectiveness of lifestyle programs for…
- Trial name
- P2S2 (NCT03370419)
- Testing
- Treatment, Usual care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wayne State University
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