Clinical trials: Emergency Departments
Dyspnea, Hypercapnia
Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients
In the emergency department and intensive care unit, blood gas analysis is a crucial tool in the assessment of critically ill patients. Blood gas analysis is quick and repeatable at the bedside.
- Trial name
- NCT04409470
- Testing
- Blood gas sampling from artery and vein
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- University Hospital, Linkoeping
Respiratory Tract Infections
ADEQUATE Advanced Diagnostics for Enhanced Quality of Antibiotic Prescription
To assess the impact of rapid diagnostic testing of patients with Acute Respiratory Tract Infection (ARTI) at the emergency department, on (1) hospital admission rates and (2) antimicrobial prescriptions (days of treatment) and…
- Trial name
- ADEQUATE (NCT04547556)
- Testing
- BioFire
- Where
- 4 sites in Belgium, Hungary and 1 more
- Volunteers
- 185 people
- Sponsor
- UMC Utrecht
Sepsis
Physician Administered Antibiotics in a Prehospital Setting
Sepsis is estimated to affect more than 30 million people globally. Detecting sepsis is notoriously difficult and there are no systems in place utilize prehospitally.
- Trial name
- PANTIPS (NCT03919851)
- Testing
- Antibiotics
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Odense University Hospital
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Migraine Disorders
Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache
The purpose of this study is to determine which drug makes lower migraine headache
- Trial name
- NCT01791400
- Testing
- metoclopramide, injection,20mg, one time, Sumatriptan, injection, 6 mg, one time
- Where
- Iran
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Nausea and Vomiting
Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department
This study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.
- Trial name
- NCT00590317
- Testing
- Prochlorperazine, Ondansetron
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Cholecystitis, Acute Cholecystitis With Obstruction
Patient Satisfaction After Ambulatory Emergency Laparoscopic Cholecystectomy
Acute cholecystitis is a common surgical emergency that, if left untreated, can result in significant morbidity and even death. It is characterized by inflammation of the gallbladder, usually caused by gallstones.
- Trial name
- NCT07616713
- Testing
- Laparoscopic Cholecystectomy
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Arthritis, Joint Pain
Ultrasound Guided Arthrocentesis
Does ultrasound guidance improve success rate and decrease aspiration attempts for peripheral arthrocentesis?
- Trial name
- UGA (NCT00537589)
- Testing
- Ultrasound guided arthrocentesis
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Wake Forest University Health Sciences
Sepsis
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging.
- Trial name
- Code Sepsis (NCT04148989)
- Testing
- Code Sepsis protocol (full implementation)
- Where
- 3 sites in United States
- Volunteers
- 180,402 people
- Sponsor
- Intermountain Health Care, Inc.
Acute Pain
Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain
The purpose of this study is to determine the safety and speed of onset of 2mg intravenous hydromorphone (Dilaudid) in patients weighing at least 150 lbs presenting to the emergency department with acute severe pain
- Trial name
- NCT00305110
- Testing
- 2 mg IV hydromorphone
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Drug Interactions, Hypertension
Interactions Between Antihypertensive Drugs and Drugs Prescribed in the Emergency Room
Drug interactions (IFF) are events that occur when multiple drugs are administered at the same time to an individual. People with arterial hypertension generally require therapeutic regimens based on 2 or more drugs for their…
- Trial name
- NCT05140590
- Where
- Mexico
- Volunteers
- 53 people
- Sponsor
- Instituto Mexicano del Seguro Social
Emergency Contraception, Contraception
Continued Use of Effective Contraception After Use of Emergency Contraception
Women using an emergency contraceptive method must use back up protection for 1-2 weeks depending on method. The Copper-IUD is the most effective emergency contraceptive method.
- Conditions
- Emergency Contraception, Contraception, Reproductive Health
- Trial name
- NCT02078414
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Karolinska Institutet
Dental Anxiety, Dental Fear
Dental Anxiety in Children Attending Emergency Versus Routine Dental Care
The goal of this observational study is to learn whether children who come to a pediatric dental emergency clinic have higher dental anxiety than children who come for routine dental care.
- Trial name
- NCT07882914
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Marmara University
Empathy
The Impact of Emergency Physician Empathy on Litigation Propensity
The purpose of this study is to observe whether people would report being less likely to sue a physician who shows more empathy when giving a patient potentially bad news regarding their medical condition.
- Trial name
- NCT01837706
- Where
- United States
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Chronic Pain, Peer Review, Health Care
Evaluation of a Interdisciplinary Pain Program Among Patients With Chronic Pain and Frequent Emergency Department Visits
While significant advances in pain management have occurred in the last 20 years, the majority of patients with chronic pain (CP) are unable to access evidence-based treatment at either the primary or tertiary care level.
- Conditions
- Chronic Pain, Peer Review, Health Care, Interdisciplinary Communication
- Trial name
- CIPAP (NCT02237391)
- Testing
- CIPAP Program, Treatment as Usual (TAU)
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Ottawa Hospital Research Institute
Postoperative Pain
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
The cesarean section is one of the most commonly performed surgeries in the world and it represents 20% of the births in France. Postoperative pain is moderate-to-severe during the first 48 hours after this procedure.
- Trial name
- ROMANCE (NCT02410317)
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Grenoble
Sciatica Acute, Sciatica Pain
Ultrasound-guided Transgluteal Sciatic Nerve Hydrodissection for the Treatment of Sciatica in the Emergency Department
The goal of this observational study is to see whether it would be feasible to treat patients who come to the emergency department with pain related to sciatica using an ultrasound guided injection of dextrose in water solution…
- Trial name
- NCT07588126
- Testing
- Ultrasound guided transgluteal sciatic nerve hydrodissection
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Kaiser Permanente
Emergencies
Study to Evaluate Satisfaction Using Personal Health Wallet Service
The investigators developed the service showing patient health record altogether which is managed by each hospital separately and recording the patient health information based on mobile application.
- Trial name
- NCT04180618
- Testing
- Personal health wallet service for emergency situation
- Where
- South Korea
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Acute Kidney Injury Following Administration of Contrast Media
Comparison of Bolus and Continuous Hydration Regimens for the Prevention of Contrast-Associated Acute Kidney Injury in the Emergency Department
A single-center, prospective, open-label, non-inferiority randomized controlled clinical trial was conducted at the ED of a tertiary hospital.
- Trial name
- NCT07286526
- Testing
- Bolus hydration therapy, Continuous hydration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people
- Sponsor
- Yunus Emre Gemici
Inflammation
Role of Faecal Calprotectin in Patients With Abdominal Pain
The evaluation of patients with abdominal pain is a challenge for the emergency physician and the selection of patients for second-level radiological examinations or endoscopic procedures is not always easy to perform.
- Trial name
- NCT05795985
- Testing
- calprotectin levels
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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