Clinical trials: Emergency Departments
Infection, Hypervolemia
Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients
The overall goal of this multicenter project is to characterize the expected normal range of Peripheral IntraVenous Volume Analysis (PIVA) values during a euvolemic state, and how those ranges may be altered by comorbidities; the…
- Conditions
- Infection, Hypervolemia, Hypovolemia, Septic Shock
- Trial name
- PIVA (NCT03736421)
- Testing
- Peripheral Intravenous Analysis (PIVA), Non-invasive fluid response measure, Passive leg raise (PLR)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Emergency Medicine
International Big Data Centre in Emergency Medicine
This observational study aims to use electronic health records to build an International Big Data Centre in Emergency Medicine, within the Institute of Sciences in Emergency Medicine (ISEM) at the Guangdong Provincial People's…
- Trial name
- NCT05616416
- Where
- China
- Volunteers
- 500,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Sepsis, Severe Sepsis
TRIAGE: TRIage of Sepsis At emerGency dEpartment
Sepsis is a serious systemic disease defined as a combination of Systemic Inflammation Response Syndrome (SIRS) plus a confirmed or suspected infection.
- Trial name
- TRIAGE (NCT02739152)
- Where
- 14 sites in Belgium, France
- Volunteers
- 602 people
- Sponsor
- BioMérieux
Cellulitis
Effect of Teledermatology on Length of Hospital Admission, Length of Stay, 30 Day Readmission Rate, and Antibiotic Use in Patients Presenting With Cellulitis vs Pseudocellulitis in an Academic ED Setting
The effect of teledermatology on length of hospital admission, length of stay, 30 day readmission rate, and antibiotic use in patients presenting with cellulitis vs pseudocellulitis in an academic emergency department setting.
- Trial name
- NCT03036358
- Testing
- teledermatology consult, Routine Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cervical Cancer Screening, Human Papilloma Virus
Developing and Implementing HPV SCREENED
This study will assess the feasibility of implementing HPV self-sampling as a primary cervical cancer screening strategy for under-screened women in the emergency department (ED).
- Trial name
- NCT07657104
- Testing
- HPV Self-collection in the ED
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Intravenous Access
Ultrasound-Guided Peripheral Venous Access Using AccuCath
While peripheral venous cannulation is among the most common procedures performed in clinical settings, it is estimated that PIV insertion fails for 6 million patients annually.
- Trial name
- AccuCath (NCT02469038)
- Testing
- AccuCath catheter, Control
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Psychological Distress, COVID-19 Infection
Emotional Changes Between Emergency and Intensive Care Unit and On-site Counter Staffs After COVID-19 Infection
The emotional and work changes of the staffs and the on-site counter staffs will have a certain impact during this pandemic period.
- Conditions
- Psychological Distress, COVID-19 Infection, Anxiety and Fear-Related Disorders
- Trial name
- COVID-19 (NCT05908058)
- Testing
- Emotional Changes Investigation
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- St. Martin De Porress Hospital
Acute Disease
High-risk Antithrombotic Drugs at Discharge and Consultation for Hemorrhagic or Thromboembolic Events in the Emergency Department
This observational study aims to estimate the proportion of patients discharged from a hospital with a prescription for anticoagulant medication who subsequently visit the emergency department due to an adverse thrombotic or…
- Trial name
- NCT07278648
- Testing
- Antithrombotic therapy
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Pain
Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
Background: Inadequate pain management is common in the Emergency Department (ED). Optimal treatment of pain necessitates titration to effective dose due to the large inter-individual variability in opioid requirement.
- Trial name
- NCT01775371
- Testing
- Patient controlled analgesia (PCA), Usual Care
- Where
- 3 sites in United States
- Volunteers
- 636 people
- Sponsor
- Albert Einstein College of Medicine
Acute Heart Failure
Acute Heart Failure Patients With High Copeptin Treated With Tolvaptan Targets Increased AVP Activation for Treatment (ACTIVATE)
Patients being hospitalized for acute heart failure and already receiving standard therapy will be randomized to receive either tolvaptan or placebo, based on the level of copeptin measured in their bloodstream.
- Trial name
- ACTIVATE (NCT01733134)
- Testing
- Tolvaptan
- Sponsor
- Maisel, Alan, M.D.
Health Related Social Needs (HRSN), Pharmacy
Pharmacist-Led SDoH Screening Intervention During Transitions of Care in an Acute Care Setting
The study is a quasi-experimental pilot study conducted at Buffalo General Medical Center (BGMC). It aims to evaluate the feasibility, acceptability, and effectiveness of a pharmacist-led intervention addressing health-related…
- Conditions
- Health Related Social Needs (HRSN), Pharmacy, Medication Reconciliation
- Trial name
- NCT06802393
- Testing
- Intervention
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- State University of New York at Buffalo
Peritonitis, Surgical Site Infection
NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis
The study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.
- Conditions
- Peritonitis, Surgical Site Infection, Infections, Wound Infection
- Trial name
- PRISTINE (NCT05684198)
- Testing
- subcutaneous NPWT
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Acute Stress Disorder, Post Traumatic Stress Disorder PTSD
Assessment of the Preventive Effect of Defusing on Traumatic Kindling
The exposure to a potential traumatic event (PTE) is common in the general population. This exposure may lead to psychiatric disorders such as acute stress disorder (ASD) and post-traumatic stress disorder (PTSD).
- Trial name
- PREDEKIT (NCT07850193)
- Testing
- Defusing, Psychological First Aid (PFA)
- Where
- 4 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Knowledge, Attitudes, Practice
GEMAS Proyect. Gamification in Nursing and Medicine for Simulation Learning.
The GEMAS project is based on the creation of a virtual serious game in which, by carrying out clinical cases that simulate real environments and episodes of a hospital emergency service, the aim is to improve and reinforce the…
- Trial name
- NCT06516250
- Testing
- Virtual serious game GEMAS
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Surgery, Diverticulitis
Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation
The purpose of this multi-center randomized trial is to identify any differences in the complication rates of patients undergoing Hartmann's (end colostomy) versus Primary Anastomosis (with defunctioning ileostomy) for left-sided…
- Conditions
- Surgery, Diverticulitis, Neoplasms, Postoperative Complications
- Trial name
- ColonPerfRCT (NCT01233713)
- Testing
- Hartmann's operation, Primary anastomosis
- Where
- 4 sites in Switzerland
- Volunteers
- 62 people
- Sponsor
- University of Zurich
Gastric Content, Full Stomach Status
Evaluation of Antral Ultrasonography for Full Stomach Diagnosis Before Pediatric Surgical Emergencies
This study evaluates antral ultrasonography for the diagnosis of full stomach before surgical emergencies in pediatric population.
- Trial name
- NCT02936882
- Testing
- Preoperative gastric ultrasonography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hôpital Necker-Enfants Malades
Human Immunodeficiency Virus
Mater-Bronx Rapid HIV Testing Project.
In the M-BRiHT study we aim to implement a programme of opportunistic HIV screening in the Emergency Department, Mater Misericordiae University Hospital.
- Trial name
- M-BRiHT (NCT01778374)
- Testing
- No participant choice of counselor, Participant choice of counselor
- Where
- Ireland
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Von Willebrand Disease
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
The main aim of the study is to check effectiveness, side effects, and tolerability of vonicog alfa (recombinant von Willebrand factor [rVWF]), with or without ADVATE, in the treatment and control of nonsurgical bleeding events…
- Trial name
- NCT02932618
- Testing
- Vonicog alfa, Antihemophilic Factor (Recombinant)
- Where
- 46 sites in United States, Austria and 11 more
- Volunteers
- 47 people
- Sponsor
- Baxalta now part of Shire
Missed Pulmonary Embolism at the Emergency Department
Characteristics of Patients With Missed Pulmonary Embolism in the ED: A Three Year Experience
The clinical presentation of acute pulmonary embolism ranges from mild dyspnea and cough to shock or sustained hypotension but it also may even be asymptomatic and diagnosed by imaging procedures performed for other purposes.
- Trial name
- NCT02476721
- Testing
- detection of pulmonary embolism
- Volunteers
- 1,251 people
- Sponsor
- University Hospital, Basel, Switzerland
Headache, Emergencies
Predictive Score for Non-traumatic Secondary Headache After an Emergency Call
The study objective was to identify predictive criteria of severe non-traumatic secondary headache among the information gathered during telephone interview conducted by the on-call regulating physician at the Centre15.
- Trial name
- CEPHAREG (NCT04617808)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 715 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
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